{"id":"https://openalex.org/W1993150907","doi":"https://doi.org/10.1117/12.2082599","title":"3D active shape models of human brain structures: application to patient-specific mesh generation","display_name":"3D active shape models of human brain structures: application to patient-specific mesh generation","publication_year":2015,"publication_date":"2015-03-20","ids":{"openalex":"https://openalex.org/W1993150907","doi":"https://doi.org/10.1117/12.2082599","mag":"1993150907"},"language":"en","primary_location":{"id":"doi:10.1117/12.2082599","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2082599","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073918042","display_name":"Nishant Ravikumar","orcid":"https://orcid.org/0000-0003-0134-107X"},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nishant Ravikumar","raw_affiliation_strings":["The Univ. of Sheffield (United Kingdom)","The University of Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Univ. of Sheffield (United Kingdom)","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"The University of Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008093681","display_name":"Isaac Castro-Mateos","orcid":"https://orcid.org/0000-0002-2745-426X"},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Isaac Castro-Mateos","raw_affiliation_strings":["The Univ. of Sheffield (United Kingdom)","The University of Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Univ. of Sheffield (United Kingdom)","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"The University of Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078441502","display_name":"Jos\u00e9 M. Pozo","orcid":"https://orcid.org/0000-0002-0759-3510"},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jose M. Pozo","raw_affiliation_strings":["The Univ. of Sheffield (United Kingdom)","The University of Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Univ. of Sheffield (United Kingdom)","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"The University of Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049192404","display_name":"Alejandro F. Frangi","orcid":"https://orcid.org/0000-0002-2675-528X"},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alejandro F. Frangi","raw_affiliation_strings":["The Univ. of Sheffield (United Kingdom)","The University of Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Univ. of Sheffield (United Kingdom)","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"The University of Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055587668","display_name":"Zeike A. Taylor","orcid":"https://orcid.org/0000-0002-0718-1663"},"institutions":[{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Zeike A. Taylor","raw_affiliation_strings":["The Univ. of Sheffield (United Kingdom)","The University of Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Univ. of Sheffield (United Kingdom)","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"The University of Sheffield, United Kingdom","institution_ids":["https://openalex.org/I91136226"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1872,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.57594999,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"9414","issue":null,"first_page":"94142D","last_page":"94142D"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10719","display_name":"3D Shape Modeling and Analysis","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7368679642677307},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5797262191772461},{"id":"https://openalex.org/keywords/point-distribution-model","display_name":"Point distribution model","score":0.5171891450881958},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4728047251701355},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4699568748474121},{"id":"https://openalex.org/keywords/brain-atlas","display_name":"Brain atlas","score":0.45675453543663025},{"id":"https://openalex.org/keywords/mesh-generation","display_name":"Mesh generation","score":0.4342740774154663},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.36620187759399414},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3285079896450043},{"id":"https://openalex.org/keywords/finite-element-method","display_name":"Finite element method","score":0.15864670276641846}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7368679642677307},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5797262191772461},{"id":"https://openalex.org/C118317068","wikidata":"https://www.wikidata.org/wiki/Q2100760","display_name":"Point distribution model","level":2,"score":0.5171891450881958},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4728047251701355},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4699568748474121},{"id":"https://openalex.org/C2780972224","wikidata":"https://www.wikidata.org/wiki/Q17047956","display_name":"Brain atlas","level":2,"score":0.45675453543663025},{"id":"https://openalex.org/C181145010","wikidata":"https://www.wikidata.org/wiki/Q4418033","display_name":"Mesh generation","level":3,"score":0.4342740774154663},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.36620187759399414},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3285079896450043},{"id":"https://openalex.org/C135628077","wikidata":"https://www.wikidata.org/wiki/Q220184","display_name":"Finite element method","level":2,"score":0.15864670276641846},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1117/12.2082599","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2082599","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.atira.dk:publications/54e15101-f1ad-4fd0-87ab-59005216683b","is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/54e15101-f1ad-4fd0-87ab-59005216683b","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ravikumar , N , Castro-Mateos , I , Pozo , J M , Frangi , A F & Taylor , Z A 2015 , 3D active shape models of human brain structures : Application to patient-specific mesh generation . in L M Hadjiiski & G D Tourassi (eds) , Medical Imaging 2015 : Computer-Aided Diagnosis . , 94142D , Progress in Biomedical Optics and Imaging - Proceedings of SPIE , vol. 9414 , SPIE , SPIE Medical Imaging Symposium 2015: Computer-Aided Diagnosis , Orlando , United States , 22/02/15 . https://doi.org/10.1117/12.2082599","raw_type":"contributionToPeriodical"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5299999713897705}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1663973292","https://openalex.org/W1667854146","https://openalex.org/W1826158161","https://openalex.org/W2021265404","https://openalex.org/W2031185944","https://openalex.org/W2038952578","https://openalex.org/W2071881327","https://openalex.org/W2104276184","https://openalex.org/W2110346973","https://openalex.org/W2113160297","https://openalex.org/W2125947475","https://openalex.org/W2134236847","https://openalex.org/W2142445683","https://openalex.org/W2142853128","https://openalex.org/W2168907905","https://openalex.org/W2171490473","https://openalex.org/W2494922686","https://openalex.org/W4236969948","https://openalex.org/W4256188663","https://openalex.org/W6638740917","https://openalex.org/W6658411549","https://openalex.org/W6676360970","https://openalex.org/W6677201605","https://openalex.org/W6685064473"],"related_works":["https://openalex.org/W2126962853","https://openalex.org/W1556115359","https://openalex.org/W2991741829","https://openalex.org/W163082481","https://openalex.org/W2564545579","https://openalex.org/W2099480728","https://openalex.org/W2479601757","https://openalex.org/W35828208","https://openalex.org/W2374835780","https://openalex.org/W103634839"],"abstract_inverted_index":{"The":[0,74,124,215],"use":[1],"of":[2,29,32,37,69,77,101,155,187,212,233],"biomechanics-based":[3],"numerical":[4],"simulations":[5],"has":[6],"attracted":[7],"growing":[8],"interest":[9,78],"in":[10,21,210],"recent":[11],"years":[12],"for":[13,25,43,94],"computer-aided":[14],"diagnosis":[15],"and":[16,40,89,105,119,142,170,174,184,190,194,223,252],"treatment":[17],"planning.":[18],"With":[19],"this":[20],"mind,":[22],"a":[23,66],"method":[24,118],"automatic":[26],"mesh":[27],"generation":[28],"brain":[30,75,130,180],"structures":[31,76,181],"interest,":[33],"using":[34,61,247],"statistical":[35],"models":[36,55],"shape":[38],"(SSM)":[39],"appearance":[41],"(SAM),":[42],"personalised":[44],"computational":[45],"modelling":[46],"is":[47,132,140,204,218,224],"presented.":[48],"SSMs":[49],"are":[50,59,103,176,192,245],"constructed":[51],"as":[52],"point":[53],"distribution":[54],"(PDMs)":[56],"while":[57],"SAMs":[58],"trained":[60,240],"intensity":[62],"profiles":[63],"sampled":[64],"from":[65,238],"training":[67,99,146,153,163],"set":[68,100,154,164],"T1-weighted":[70],"magnetic":[71],"resonance":[72],"images.":[73],"are,":[79],"the":[80,98,111,136,152,162,168,188,199,229,234,239,248],"cortical":[81],"surface":[82,255],"(cerebrum,":[83],"cerebellum":[84],"&":[85],"brainstem),":[86],"lateral":[87],"ventricles":[88],"falx-cerebri":[90],"membrane.":[91],"Two":[92],"methods":[93],"establishing":[95],"correspondences":[96],"across":[97],"shapes":[102],"investigated":[104],"compared":[106],"(based":[107],"on":[108],"SSM":[109,169,208,217],"quality):":[110],"Coherent":[112],"Point":[113],"Drift":[114],"(CPD)":[115],"point-set":[116],"registration":[117,122],"B-spline":[120],"mesh-to-mesh":[121],"method.":[123],"MNI-305":[125],"(Montreal":[126],"Neurological":[127],"Institute)":[128],"average":[129],"atlas":[131],"used":[133,165,195,205],"to":[134,144,148,166,196,206,220,228,242],"generate":[135,167],"template":[137],"mesh,":[138],"which":[139],"deformed":[141],"registered":[143],"each":[145],"case,":[147],"establish":[149],"correspondence":[150],"over":[151,178],"shapes.":[156],"18":[157],"healthy":[158],"patients\u2019":[159],"T1-weightedMRimages":[160],"form":[161],"SAM.":[171],"Both":[172],"model-training":[173],"model-fitting":[175],"performed":[177],"multiple":[179],"simultaneously.":[182],"Compactness":[183],"generalisation":[185],"errors":[186],"BSpline-SSM":[189],"CPD-SSM":[191],"evaluated":[193,246],"quantitatively":[197],"compare":[198],"SSMs.":[200],"Leave-one-out":[201],"cross":[202],"validation":[203],"evaluate":[207],"quality":[209],"terms":[211],"these":[213],"measures.":[214],"mesh-based":[216],"found":[219],"generalise":[221],"better":[222],"more":[225],"compact,":[226],"relative":[227],"CPD-based":[230],"SSM.":[231],"Quality":[232],"best-fit":[235],"model":[236],"instance":[237],"SSMs,":[241],"test":[243],"cases":[244],"Hausdorff":[249],"distance":[250,256],"(HD)":[251],"mean":[253],"absolute":[254],"(MASD)":[257],"metrics.":[258]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}