{"id":"https://openalex.org/W4362603595","doi":"https://doi.org/10.1117/12.2651940","title":"Integrative risk predictors of temporomandibular joint osteoarthritis progression","display_name":"Integrative risk predictors of temporomandibular joint osteoarthritis progression","publication_year":2023,"publication_date":"2023-04-03","ids":{"openalex":"https://openalex.org/W4362603595","doi":"https://doi.org/10.1117/12.2651940","pmid":"https://pubmed.ncbi.nlm.nih.gov/38533187"},"language":"en","primary_location":{"id":"doi:10.1117/12.2651940","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1117/12.2651940","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2023: Image Processing","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10964797/pdf/nihms-1978663.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034067147","display_name":"Lingrui Cai","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Lingrui Cai","raw_affiliation_strings":["Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, Ann Arbor, 48109, MI,USA"],"affiliations":[{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, Ann Arbor, 48109, MI,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085839835","display_name":"Najla Al Turkestani","orcid":"https://orcid.org/0000-0002-7650-3638"},"institutions":[{"id":"https://openalex.org/I185163786","display_name":"King Abdulaziz University","ror":"https://ror.org/02ma4wv74","country_code":"SA","type":"education","lineage":["https://openalex.org/I185163786"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Najla Al Turkestani","raw_affiliation_strings":["Department of Orthodontics and Pediatric Dentistry, University of Michigan, 1011 North University Ave, Ann Arbor, 48109, MI, USA","Department of Restorative and Aesthetic Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, 22252, Saudi Arabia"],"affiliations":[{"raw_affiliation_string":"Department of Orthodontics and Pediatric Dentistry, University of Michigan, 1011 North University Ave, Ann Arbor, 48109, MI, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Restorative and Aesthetic Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, 22252, Saudi Arabia","institution_ids":["https://openalex.org/I185163786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066883487","display_name":"Luc\u00eda Cevidanes","orcid":"https://orcid.org/0000-0001-9786-2253"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucia Cevidanes","raw_affiliation_strings":["Department of Orthodontics and Pediatric Dentistry, University of Michigan, 1011 North University Ave, Ann Arbor, 48109, MI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Orthodontics and Pediatric Dentistry, University of Michigan, 1011 North University Ave, Ann Arbor, 48109, MI, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004599808","display_name":"Jonas Bianchi","orcid":"https://orcid.org/0000-0002-3749-0918"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonas Bianchi","raw_affiliation_strings":["Department of Orthodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, 155 5th St, San Francisco, 94103, CA, United States"],"affiliations":[{"raw_affiliation_string":"Department of Orthodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, 155 5th St, San Francisco, 94103, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086535340","display_name":"Marcela Gurgel","orcid":"https://orcid.org/0000-0001-9978-0542"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcela Gurgel","raw_affiliation_strings":["Department of Orthodontics and Pediatric Dentistry, University of Michigan, 1011 North University Ave, Ann Arbor, 48109, MI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Orthodontics and Pediatric Dentistry, University of Michigan, 1011 North University Ave, Ann Arbor, 48109, MI, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067697464","display_name":"Kayvan Najarian","orcid":"https://orcid.org/0000-0003-4485-6612"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kayvan Najarian","raw_affiliation_strings":["Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, Ann Arbor, 48109, MI,USA"],"affiliations":[{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, Ann Arbor, 48109, MI,USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023608941","display_name":"S. M. Reza Soroushmehr","orcid":"https://orcid.org/0000-0001-8417-9260"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Reza Soroushmehr","raw_affiliation_strings":["Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, Ann Arbor, 48109, MI,USA"],"affiliations":[{"raw_affiliation_string":"Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, Ann Arbor, 48109, MI,USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5034067147"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2745,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.56010745,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"97","issue":null,"first_page":"58","last_page":"58"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10852","display_name":"Temporomandibular Joint Disorders","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/3603","display_name":"Complementary and Manual Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10852","display_name":"Temporomandibular Joint Disorders","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/3603","display_name":"Complementary and Manual Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoarthritis","display_name":"Osteoarthritis","score":0.7268146872520447},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.652675211429596},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.6164788603782654},{"id":"https://openalex.org/keywords/temporomandibular-joint","display_name":"Temporomandibular joint","score":0.586226761341095},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5859863758087158},{"id":"https://openalex.org/keywords/lasso","display_name":"Lasso (programming language)","score":0.571977436542511},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5619354248046875},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.49691298604011536},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.42350178956985474},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.386020690202713},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3489748537540436},{"id":"https://openalex.org/keywords/orthodontics","display_name":"Orthodontics","score":0.21549919247627258},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.17946338653564453}],"concepts":[{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.7268146872520447},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.652675211429596},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.6164788603782654},{"id":"https://openalex.org/C2780202543","wikidata":"https://www.wikidata.org/wiki/Q827134","display_name":"Temporomandibular joint","level":2,"score":0.586226761341095},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5859863758087158},{"id":"https://openalex.org/C37616216","wikidata":"https://www.wikidata.org/wiki/Q3218363","display_name":"Lasso (programming language)","level":2,"score":0.571977436542511},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5619354248046875},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.49691298604011536},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.42350178956985474},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.386020690202713},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3489748537540436},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.21549919247627258},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.17946338653564453},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2651940","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1117/12.2651940","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2023: Image Processing","raw_type":"proceedings-article"},{"id":"pmid:38533187","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38533187","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10964797","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10964797","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10964797/pdf/nihms-1978663.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10964797","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10964797","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10964797/pdf/nihms-1978663.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.49000000953674316,"display_name":"Life in Land"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4362603595.pdf"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1545142063","https://openalex.org/W1970396247","https://openalex.org/W2078091518","https://openalex.org/W2131987814","https://openalex.org/W2143426320","https://openalex.org/W2522694580","https://openalex.org/W2570499938","https://openalex.org/W2589270911","https://openalex.org/W2600746833","https://openalex.org/W2941139002","https://openalex.org/W3016852027","https://openalex.org/W3025590102","https://openalex.org/W4210395023","https://openalex.org/W4237672378","https://openalex.org/W4285377895","https://openalex.org/W4293067524","https://openalex.org/W6678577963","https://openalex.org/W6717827561"],"related_works":["https://openalex.org/W2380784125","https://openalex.org/W4388745254","https://openalex.org/W2980082554","https://openalex.org/W1517228774","https://openalex.org/W2767419625","https://openalex.org/W2389704471","https://openalex.org/W2810025138","https://openalex.org/W1997711767","https://openalex.org/W2117019857","https://openalex.org/W2344475471"],"abstract_inverted_index":{"In":[0,26],"this":[1],"paper":[2],"we":[3],"propose":[4],"feature":[5,36],"selection":[6,37],"and":[7,33,48,57,61,65,77,85,111,116,136,145,158,160,165],"machine":[8],"learning":[9,74],"approaches":[10,89],"to":[11,90,177],"identify":[12],"a":[13,27],"combination":[14],"of":[15,20,29,38,73,113,122,154,163],"features":[16,47,176],"for":[17],"risk":[18],"prediction":[19],"Temporomandibular":[21],"Joint":[22],"(TMJ)":[23],"disease":[24,92],"progression.":[25],"sample":[28],"32":[30],"TMJ":[31,181],"osteoarthritis":[32,182],"38":[34],"controls,":[35],"5":[39],"clinical":[40],"comorbidities,":[41],"43":[42],"quantitative":[43],"imaging,":[44],"28":[45],"biological":[46],"was":[49],"performed":[50],"using":[51,75,102],"Maximum":[52],"Relevance":[53],"Minimum":[54],"Redundancy,":[55],"Chi-Square":[56],"Least":[58],"Absolute":[59],"Shrinkage":[60],"Selection":[62],"Operator":[63],"(LASSO)":[64],"Recursive":[66],"Feature":[67],"Elimination.":[68],"We":[69,96],"compared":[70],"the":[71,99,107,172],"performance":[72],"concave":[76],"convex":[78],"kernels":[79],"(LUCCK),":[80],"Support":[81],"Vector":[82],"Machine":[83],"(SVM)":[84],"Random":[86],"Forest":[87],"(RF)":[88],"predict":[91,178],"cure/improvement":[93],"or":[94],"persistence/worsening.":[95],"show":[97],"that":[98],"SVM":[100],"model":[101],"LASSO":[103],"achieves":[104],"area":[105],"under":[106],"curve":[108],"(AUC),":[109],"sensitivity":[110],"precision":[112],"0.92\u00b10.08,":[114],"0.85\u00b10.19":[115],"0.76":[117],"\u00b10.18,":[118],"respectively.":[119],"Baseline":[120],"levels":[121,153,162],"headaches,":[123],"lower":[124],"back":[125],"pain,":[126],"restless":[127],"sleep,":[128],"muscle":[129],"soreness,":[130],"articular":[131],"fossa":[132],"bone":[133],"surface/bone":[134],"volume":[135],"trabecular":[137],"separation,":[138],"condylar":[139],"High":[140,148],"Gray":[141,149],"Level":[142,150],"Run":[143,147],"Emphasis":[144],"Short":[146],"Emphasis,":[151],"saliva":[152],"6Ckine,":[155],"Osteoprotegerin":[156],"(OPG)":[157],"Angiogenin,":[159],"serum":[161],"6ckine":[164],"Brain":[166],"Derived":[167],"Neurotrophic":[168],"Factor":[169],"(BDNF)":[170],"were":[171],"most":[173],"frequently":[174],"occurring":[175],"more":[179],"severe":[180],"prognosis.":[183]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-03-13T16:22:10.518609","created_date":"2025-10-10T00:00:00"}