{"id":"https://openalex.org/W4221036238","doi":"https://doi.org/10.1117/12.2613210","title":"Local extraction of extra-axial CSF from structural MRI","display_name":"Local extraction of extra-axial CSF from structural MRI","publication_year":2022,"publication_date":"2022-03-30","ids":{"openalex":"https://openalex.org/W4221036238","doi":"https://doi.org/10.1117/12.2613210","pmid":"https://pubmed.ncbi.nlm.nih.gov/35720673"},"language":"en","primary_location":{"id":"doi:10.1117/12.2613210","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2613210","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9205333","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079468110","display_name":"Tahya Deddah","orcid":null},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tahya Deddah","raw_affiliation_strings":["Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065838160","display_name":"Martin Styner","orcid":"https://orcid.org/0000-0002-8747-5118"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4210158053","display_name":"University of North Carolina System","ror":"https://ror.org/0566a8c54","country_code":"US","type":"education","lineage":["https://openalex.org/I4210158053"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Styner","raw_affiliation_strings":["Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4210158053"]},{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101841407","display_name":"Juan Carlos Prieto","orcid":"https://orcid.org/0000-0002-3778-9098"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan Carlos Prieto","raw_affiliation_strings":["Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0985,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.33410231,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"10","issue":null,"first_page":"9","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.742374062538147},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"Cerebrospinal fluid","score":0.7188654541969299},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7037001848220825},{"id":"https://openalex.org/keywords/subarachnoid-space","display_name":"Subarachnoid space","score":0.6362173557281494},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.6116741895675659},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4517367482185364},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.347541868686676},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.28123247623443604},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.2798917293548584},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.21429035067558289},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10012611746788025}],"concepts":[{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.742374062538147},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.7188654541969299},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7037001848220825},{"id":"https://openalex.org/C2780813603","wikidata":"https://www.wikidata.org/wiki/Q268930","display_name":"Subarachnoid space","level":3,"score":0.6362173557281494},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6116741895675659},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4517367482185364},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.347541868686676},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.28123247623443604},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2798917293548584},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21429035067558289},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10012611746788025},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2613210","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2613210","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging","raw_type":"proceedings-article"},{"id":"pmid:35720673","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35720673","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9205333","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9205333","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9205333","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9205333","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1829164554","display_name":null,"funder_award_id":"P50 HD103573","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G1989292043","display_name":null,"funder_award_id":"U54 HD079124","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G2530918640","display_name":null,"funder_award_id":"R01 MH104324","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G2735621601","display_name":null,"funder_award_id":"R01 MH115046","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G2827497159","display_name":null,"funder_award_id":"R01 MH118362","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G2902230680","display_name":null,"funder_award_id":"K12 HD001441","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G4139504844","display_name":null,"funder_award_id":"R01 HD055741","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G476217200","display_name":null,"funder_award_id":"R01 EB021391","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G5369696504","display_name":null,"funder_award_id":"R56 EB021391","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G597442328","display_name":null,"funder_award_id":"U01 MH110274","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G694253131","display_name":null,"funder_award_id":"P30 HD003110","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1969576961","https://openalex.org/W2905338705","https://openalex.org/W3003790196","https://openalex.org/W3007842898","https://openalex.org/W3091089282","https://openalex.org/W6642574270","https://openalex.org/W6757190006","https://openalex.org/W6774803518","https://openalex.org/W6784239798"],"related_works":["https://openalex.org/W2415383105","https://openalex.org/W2764334540","https://openalex.org/W4293097560","https://openalex.org/W2045401688","https://openalex.org/W1972670736","https://openalex.org/W4214811308","https://openalex.org/W1543460188","https://openalex.org/W2470064111","https://openalex.org/W2523201464","https://openalex.org/W2970350427"],"abstract_inverted_index":{"The":[0,136,197],"quantification":[1,73,128],"of":[2,24,39,54,67,120,138,166,173,182,208],"cerebrospinal":[3,9],"fluid":[4,10],"(CSF),":[5],"specifically":[6],"the":[7,14,17,21,25,37,51,63,68,158,180,183,194,228],"extra-axial":[8,209],"(EA-CSF),":[11],"which":[12,156],"is":[13,141],"CSF":[15,210],"in":[16,36,44,116,211,215,221],"subarachnoid":[18],"space":[19],"surrounding":[20],"cortical":[22,102],"surface":[23,103],"brain,":[26],"has":[27],"recently":[28],"been":[29],"shown":[30],"to":[31,142,160,178,193,203,217],"play":[32],"an":[33,163],"important":[34],"role":[35,220],"neuropathology":[38],"autism":[40],"spectrum":[41],"disorder":[42],"(ASD)":[43],"infants.":[45],"While":[46],"prior":[47,195],"work":[48],"addressed":[49],"measuring":[50],"global":[52],"volume":[53],"EA-CSF,":[55],"there":[56],"was":[57],"no":[58],"available":[59,121,151],"tool":[60,187,199],"that":[61,96,111],"quantifies":[62],"local,":[64],"anatomical":[65],"distribution":[66],"EA-CSF.":[69],"A":[70],"localized":[71],"EA-CSF":[72,90,108,130,184],"would":[74],"provide":[75,170],"more":[76],"accurate":[77],"and":[78,105,169,191,223],"interpretable":[79],"measurements.":[80],"In":[81],"our":[82],"recent":[83],"work,":[84],"we":[85],"proposed":[86],"such":[87],"a":[88,94,118,127,144,171,205],"local":[89,107,206],"extraction":[91,207],"by":[92],"using":[93],"pipeline":[95,168],"combines":[97],"probabilistic":[98],"brain":[99,225],"tissue":[100],"segmentation,":[101],"reconstruction":[104],"streamline-based":[106],"quantification.":[109,185],"Yet,":[110],"system":[112],"had":[113],"several":[114],"shortcomings,":[115],"particular":[117],"lack":[119],"software":[122,152],"tools,":[123],"as":[124,126],"well":[125],"where":[129],"portions":[131],"are":[132],"counted":[133],"multiple":[134],"times.":[135],"purpose":[137],"this":[139,167],"article":[140],"present":[143],"novel,":[145],"graphical":[146],"user":[147,159],"interface":[148],"based,":[149],"publicly":[150],"tool,":[153],"called":[154],"LocalEACSF,":[155],"allows":[157,200],"easily":[161],"run":[162],"adapted":[164],"version":[165],"set":[172],"straightforward":[174],"quality":[175,181],"control":[176],"visualizations":[177],"assess":[179],"This":[186],"further":[188],"adds":[189],"improvements":[190],"optimizations":[192],"assessment.":[196],"LocalEACSF":[198],"neuroimaging":[201,213],"labs":[202],"compute":[204],"their":[212],"studies":[214],"order":[216],"investigate":[218],"its":[219],"normal":[222],"atypical":[224],"development,":[226],"without":[227],"need":[229],"for":[230],"extensive":[231],"technical":[232],"knowledge.":[233]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}