{"id":"https://openalex.org/W4220998636","doi":"https://doi.org/10.1117/12.2612913","title":"Bone and bone marrow segmentation from hip 3T magnetic resonance imaging by using local salient anatomy structure to guide deep learning-based object localization and delineation","display_name":"Bone and bone marrow segmentation from hip 3T magnetic resonance imaging by using local salient anatomy structure to guide deep learning-based object localization and delineation","publication_year":2022,"publication_date":"2022-03-11","ids":{"openalex":"https://openalex.org/W4220998636","doi":"https://doi.org/10.1117/12.2612913"},"language":"en","primary_location":{"id":"doi:10.1117/12.2612913","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2612913","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2022: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026454974","display_name":"Yubing Tong","orcid":null},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yubing Tong","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051036720","display_name":"Zihan Huang","orcid":"https://orcid.org/0000-0002-5781-4166"},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zihan Huang","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065713856","display_name":"Jayaram K. Udupa","orcid":"https://orcid.org/0000-0002-7361-2927"},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jayaram K. Udupa","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001865738","display_name":"Leihui Tong","orcid":null},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leihui Tong","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007906281","display_name":"Brandon C. Jones","orcid":"https://orcid.org/0000-0002-9352-5521"},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon C. Jones","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101479372","display_name":"Gregory Chang","orcid":"https://orcid.org/0000-0001-9137-8719"},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory Chang","raw_affiliation_strings":["NYU School of Medicine (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NYU School of Medicine (United States)","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080030813","display_name":"Drew A. Torigian","orcid":"https://orcid.org/0000-0001-8999-9735"},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Drew A. Torigian","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021492844","display_name":"Chamith S. Rajapakse","orcid":"https://orcid.org/0000-0002-9247-833X"},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chamith S. Rajapakse","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"77","issue":null,"first_page":"65","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12209","display_name":"Bone and Joint Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12209","display_name":"Bone and Joint Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11509","display_name":"Hip and Femur Fractures","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10512","display_name":"Orthopaedic implants and arthroplasty","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/s\u00f8rensen\u2013dice-coefficient","display_name":"S\u00f8rensen\u2013Dice coefficient","score":0.8241901397705078},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7652378678321838},{"id":"https://openalex.org/keywords/medullary-cavity","display_name":"Medullary cavity","score":0.7136982679367065},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6260098218917847},{"id":"https://openalex.org/keywords/femoral-head","display_name":"Femoral head","score":0.6228780746459961},{"id":"https://openalex.org/keywords/femur","display_name":"Femur","score":0.5951127409934998},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.4985215663909912},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49271753430366516},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.47697243094444275},{"id":"https://openalex.org/keywords/cortical-bone","display_name":"Cortical bone","score":0.45791876316070557},{"id":"https://openalex.org/keywords/acetabulum","display_name":"Acetabulum","score":0.4426426291465759},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.41772976517677307},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.40562623739242554},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.34865251183509827},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.21433037519454956},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.10347545146942139}],"concepts":[{"id":"https://openalex.org/C163892561","wikidata":"https://www.wikidata.org/wiki/Q2613728","display_name":"S\u00f8rensen\u2013Dice coefficient","level":4,"score":0.8241901397705078},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7652378678321838},{"id":"https://openalex.org/C195121873","wikidata":"https://www.wikidata.org/wiki/Q1131385","display_name":"Medullary cavity","level":2,"score":0.7136982679367065},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6260098218917847},{"id":"https://openalex.org/C2779100257","wikidata":"https://www.wikidata.org/wiki/Q582849","display_name":"Femoral head","level":2,"score":0.6228780746459961},{"id":"https://openalex.org/C2780554211","wikidata":"https://www.wikidata.org/wiki/Q176503","display_name":"Femur","level":2,"score":0.5951127409934998},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4985215663909912},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49271753430366516},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.47697243094444275},{"id":"https://openalex.org/C2781451080","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cortical bone","level":2,"score":0.45791876316070557},{"id":"https://openalex.org/C72202192","wikidata":"https://www.wikidata.org/wiki/Q16242523","display_name":"Acetabulum","level":2,"score":0.4426426291465759},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.41772976517677307},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.40562623739242554},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34865251183509827},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.21433037519454956},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.10347545146942139}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2612913","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2612913","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2022: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Decent work and economic growth","score":0.7099999785423279,"id":"https://metadata.un.org/sdg/8"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W212537071","https://openalex.org/W1957401314","https://openalex.org/W2005064230","https://openalex.org/W2012596468","https://openalex.org/W2152865402","https://openalex.org/W2400718538","https://openalex.org/W2775795276","https://openalex.org/W2788739250","https://openalex.org/W3000050577","https://openalex.org/W3007372272","https://openalex.org/W3007375197","https://openalex.org/W3025536940","https://openalex.org/W3130570865","https://openalex.org/W3131357918","https://openalex.org/W6639824700","https://openalex.org/W6747218270","https://openalex.org/W6777682288"],"related_works":["https://openalex.org/W1757525798","https://openalex.org/W2343654552","https://openalex.org/W2011802894","https://openalex.org/W2012618155","https://openalex.org/W1991364034","https://openalex.org/W2413740002","https://openalex.org/W2245723156","https://openalex.org/W4306179567","https://openalex.org/W1983591392","https://openalex.org/W2047007034"],"abstract_inverted_index":{"Currently,":[0],"3T":[1,52,113],"hip":[2,51,114],"MRI":[3,53,115],"can":[4,245],"be":[5,246],"used":[6],"to":[7,104,152,237,249],"estimate":[8],"femur":[9,72],"strength":[10],"and":[11,43,71,81,130,134,165,169,178,184,199,203,223,244],"cortical":[12,168,205],"bone":[13,171,173,190,192,206],"thickness.":[14],"One":[15],"of":[16,69,182,197,215,232],"the":[17,75,94,106,110,141,153],"major":[18],"hurdles":[19],"in":[20,121,140,253],"this":[21,37,122],"application":[22],"is":[23,221,242],"that":[24,124,146],"objects":[25],"(osseous":[26],"structures)":[27],"are":[28],"manually":[29],"segmented":[30],"which":[31],"involves":[32],"significant":[33],"human":[34],"labor.":[35],"In":[36],"study,":[38],"we":[39],"propose":[40],"an":[41],"automatic":[42,67,222],"accurate":[44],"algorithm":[45],"for":[46,89,163],"osseous":[47],"structure":[48],"segmentation":[49,148,175],"from":[50,97,156,228],"by":[54,73,101],"using":[55,74,233],"a":[56,79,102,135],"deep":[57],"convolutional":[58],"neural":[59],"network.":[60],"The":[61,143,159,218,230],"approach":[62,220],"includes":[63],"two":[64],"stages:":[65],"1)":[66],"localization":[68,95,240,251],"acetabulum":[70],"femoral":[76,98,166,185,204],"head":[77,99],"as":[78],"reference,":[80],"2)":[82],"2D":[83],"bounding":[84],"box":[85],"(BB)":[86],"set":[87],"up":[88],"each":[90],"object":[91,108,239],"based":[92],"on":[93],"information":[96],"followed":[100],"UNet":[103],"segment":[105],"target":[107],"within":[109],"BB.":[111],"90":[112],"image":[116],"data":[117],"sets":[118],"were":[119,125,150,208],"utilized":[120],"study":[123,144],"divided":[126],"into":[127],"training,":[128],"validating,":[129],"testing":[131],"groups":[132],"(60%:20%:20%),":[133],"5-fold":[136],"cross-validation":[137],"was":[138,176],"adopted":[139],"procedure.":[142],"showed":[145],"automated":[147],"results":[149],"comparable":[151],"reference":[154],"standard":[155],"manual":[157],"segmentation.":[158],"average":[160],"Dice":[161,195,213],"Coefficient":[162,196,214],"acetabular":[164,183],"(i.e.,":[167,188],"medullary":[170,186,189],"plus":[172,191],"marrow)":[174,193],"0.93":[177],"0.96,":[179],"respectively.":[180,201],"Segmentations":[181],"cavity":[187],"had":[194],"0.89":[198],"0.95,":[200],"Acetabular":[202],"segmentations":[207],"more":[209],"challenging":[210],"with":[211],"lower":[212],"around":[216],"0.7.":[217],"proposed":[219],"effective":[224],"without":[225],"any":[226],"interaction":[227],"humans.":[229],"idea":[231],"local":[234],"salient":[235],"anatomy":[236],"guide":[238],"approaches":[241],"heuristic":[243],"easily":[247],"generalized":[248],"other":[250],"problems":[252],"practice.":[254]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}