{"id":"https://openalex.org/W3131912052","doi":"https://doi.org/10.1117/12.2581077","title":"Measure partial liver volumetric variations from paired inspiratory-expiratory chest CT scans","display_name":"Measure partial liver volumetric variations from paired inspiratory-expiratory chest CT scans","publication_year":2021,"publication_date":"2021-02-12","ids":{"openalex":"https://openalex.org/W3131912052","doi":"https://doi.org/10.1117/12.2581077","mag":"3131912052","pmid":"https://pubmed.ncbi.nlm.nih.gov/34354325"},"language":"en","primary_location":{"id":"doi:10.1117/12.2581077","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2581077","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2021: Image Processing","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8336659","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089336048","display_name":"Can Luo","orcid":"https://orcid.org/0000-0002-7311-5963"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Can Luo","raw_affiliation_strings":["Data Science Institute, Vanderbilt University, Nashville, TN, 37235 USA","Data Science Institute, Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Data Science Institute, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":[]},{"raw_affiliation_string":"Data Science Institute, Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054001184","display_name":"James G. Terry","orcid":"https://orcid.org/0000-0001-6659-3441"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Terry","raw_affiliation_strings":["Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","Vanderbilt Univ. Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Vanderbilt Univ. Medical Ctr. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037478865","display_name":"Yucheng Tang","orcid":"https://orcid.org/0000-0002-6008-9700"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yucheng Tang","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044434848","display_name":"Kaiwen Xu","orcid":"https://orcid.org/0000-0002-2664-255X"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kaiwen Xu","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061560898","display_name":"Pierre P. Massion","orcid":"https://orcid.org/0000-0003-0647-0559"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pierre Massion","raw_affiliation_strings":["Division of Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt Ingram Cancer Center, Nashville, TN, USA 37235","Vanderbilt Univ. Medical Ctr., Vanderbilt Ingram Cancer Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt Ingram Cancer Center, Nashville, TN, USA 37235","institution_ids":[]},{"raw_affiliation_string":"Vanderbilt Univ. Medical Ctr., Vanderbilt Ingram Cancer Ctr. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075735203","display_name":"Bennett A. Landman","orcid":"https://orcid.org/0000-0001-5733-2127"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bennett A. Landman","raw_affiliation_strings":["Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, 37235 USA","Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","Institute of Imaging Science, Vanderbilt University, Nashville, TN, 37235 USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Institute of Imaging Science, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005915006","display_name":"J. Jeffrey Carr","orcid":"https://orcid.org/0000-0002-4398-8237"},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210150144","display_name":"LIG Science (United States)","ror":"https://ror.org/05035cc38","country_code":"US","type":"company","lineage":["https://openalex.org/I4210150144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Carr","raw_affiliation_strings":["Department of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","Institute of Imaging Science, Vanderbilt University, Nashville, TN, 37235 USA","Vanderbilt Univ. Medical Ctr. (United States)","Institute of Imaging Science (United States)","Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Institute of Imaging Science, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt Univ. Medical Ctr. (United States)","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Institute of Imaging Science (United States)","institution_ids":["https://openalex.org/I4210150144"]},{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067191302","display_name":"Yuankai Huo","orcid":"https://orcid.org/0000-0002-2096-8065"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuankai Huo","raw_affiliation_strings":["Data Science Institute, Vanderbilt University, Nashville, TN, 37235 USA","Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","Data Science Institute (United States)","Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Data Science Institute, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":[]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, 37235 USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Data Science Institute (United States)","institution_ids":[]},{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5089336048"],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":null,"apc_paid":null,"fwci":0.1494,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.473241,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"11596","issue":null,"first_page":"112","last_page":"112"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9782000184059143,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7196721434593201},{"id":"https://openalex.org/keywords/elastography","display_name":"Elastography","score":0.6523359417915344},{"id":"https://openalex.org/keywords/cirrhosis","display_name":"Cirrhosis","score":0.6062079668045044},{"id":"https://openalex.org/keywords/magnetic-resonance-elastography","display_name":"Magnetic resonance elastography","score":0.5621203780174255},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.5599866509437561},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.5480636358261108},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.4966900944709778},{"id":"https://openalex.org/keywords/transient-elastography","display_name":"Transient elastography","score":0.43189677596092224},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.3722778558731079},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"Liver fibrosis","score":0.3585429787635803},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1656365692615509}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7196721434593201},{"id":"https://openalex.org/C2777690781","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Elastography","level":3,"score":0.6523359417915344},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.6062079668045044},{"id":"https://openalex.org/C2779124084","wikidata":"https://www.wikidata.org/wiki/Q6731597","display_name":"Magnetic resonance elastography","level":4,"score":0.5621203780174255},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5599866509437561},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5480636358261108},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4966900944709778},{"id":"https://openalex.org/C2780826214","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Transient elastography","level":4,"score":0.43189677596092224},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3722778558731079},{"id":"https://openalex.org/C2994217296","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Liver fibrosis","level":3,"score":0.3585429787635803},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1656365692615509}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2581077","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2581077","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2021: Image Processing","raw_type":"proceedings-article"},{"id":"pmid:34354325","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34354325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8336659","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8336659","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8336659","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8336659","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1680164276","https://openalex.org/W1852596538","https://openalex.org/W2016974693","https://openalex.org/W2026752633","https://openalex.org/W2171925512","https://openalex.org/W2413073178","https://openalex.org/W2562842739","https://openalex.org/W2625075605","https://openalex.org/W2788102027"],"related_works":["https://openalex.org/W2321805433","https://openalex.org/W2883987361","https://openalex.org/W4390617172","https://openalex.org/W1964359360","https://openalex.org/W2895174236","https://openalex.org/W3101514091","https://openalex.org/W4387357496","https://openalex.org/W2350108069","https://openalex.org/W1601852871","https://openalex.org/W2333224701"],"abstract_inverted_index":{"Liver":[0],"stiffness":[1,26],"is":[2,58,137],"an":[3,162],"essential":[4],"clinical":[5,15,188],"biomarker":[6],"for":[7],"diagnosing":[8],"liver":[9,80,96,124,148,178],"fibrosis":[10],"and":[11,48,60,66,168],"cirrhosis.":[12],"In":[13,82],"current":[14],"practice,":[16],"elastography":[17,41,57],"techniques":[18],"are":[19],"standard":[20],"non-invasive":[21],"diagnosis":[22],"tools":[23],"to":[24,90,120,184,193],"assess":[25,91],"of":[27,95,177],"liver,":[28],"using":[29],"either":[30],"Ultrasound":[31],"(US)":[32],"or":[33],"magnetic":[34],"resonance":[35],"imaging":[36,72],"(MRI).":[37],"However,":[38],"the":[39,55,68,109,122,155,195],"US":[40,65],"yields":[42],"\u2248":[43],"10":[44],"%":[45],"failure":[46],"rate":[47],"degraded":[49],"performance":[50],"on":[51],"obese":[52],"patients,":[53],"while":[54],"MR":[56],"costlier":[59],"less":[61],"available.":[62],"Compared":[63],"with":[64,127,147],"MRI,":[67],"computerized":[69],"tomography":[70],"(CT)":[71],"has":[73],"not":[74],"been":[75],"widely":[76],"used":[77],"in":[78,197],"measuring":[79],"stiffness.":[81],"this":[83,198],"paper,":[84],"we":[85,111],"performed":[86],"a":[87,113,131],"pilot":[88,199],"study":[89],"if":[92],"volumetric":[93,125,175],"variations":[94,126,176],"can":[97],"be":[98,191],"captured":[99],"from":[100,130,150,181],"paired":[101,144],"inspiratory-expiratory":[102],"chest":[103],"(PIEC)":[104],"CT":[105,145],"scans.":[106],"To":[107],"enable":[108],"assessment,":[110],"propose":[112],"Hierarchical":[114],"Intra-Patient":[115],"Organ-specific":[116],"(HIPO)":[117],"registration":[118,158],"pipeline":[119],"quantify":[121],"partial":[123],"lung":[128],"pressure":[129],"respiratory":[132,152],"cycle.":[133],"The":[134],"PIEC":[135],"protocol":[136],"employed":[138],"since":[139],"it":[140],"naturally":[141],"provides":[142],"two":[143],"scans":[146],"deformation":[149],"regulated":[151],"motions.":[153],"For":[154],"subjects":[156],"whose":[157],"results":[159],"passed":[160],"both":[161],"automatic":[163],"quantitative":[164],"quality":[165],"assurance":[166],"(QA)":[167],"another":[169],"visual":[170],"qualitative":[171],"QA,":[172],"6.0%":[173],"average":[174],"were":[179],"measured,":[180],"inspiratory":[182],"phase":[183],"expiratory":[185],"phase.":[186],"Future":[187],"validations":[189],"will":[190],"required":[192],"validate":[194],"findings":[196],"study.":[200]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}