{"id":"https://openalex.org/W3131488428","doi":"https://doi.org/10.1117/12.2580802","title":"Ultrasound multi-needle detection using deep attention U-Net with TV regularizations","display_name":"Ultrasound multi-needle detection using deep attention U-Net with TV regularizations","publication_year":2021,"publication_date":"2021-02-12","ids":{"openalex":"https://openalex.org/W3131488428","doi":"https://doi.org/10.1117/12.2580802","mag":"3131488428"},"language":"en","primary_location":{"id":"doi:10.1117/12.2580802","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2580802","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2021: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052639870","display_name":"Yupei Zhang","orcid":"https://orcid.org/0000-0001-8348-0545"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yupei Zhang","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011903902","display_name":"Yang Lei","orcid":"https://orcid.org/0000-0002-3572-0345"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Lei","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034119956","display_name":"Xiuxiu He","orcid":"https://orcid.org/0000-0002-8559-9520"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiuxiu He","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101311536","display_name":"Zhen Tian","orcid":"https://orcid.org/0009-0009-2962-6334"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhen Tian","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073568235","display_name":"Jiwoong Jeong","orcid":"https://orcid.org/0000-0001-5630-9443"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiwoong Jeong","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049656223","display_name":"Tonghe Wang","orcid":"https://orcid.org/0000-0001-9021-1204"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tonghe Wang","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060828548","display_name":"Qiulan Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qiulan Zeng","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112746616","display_name":"Ashesh B. Jani","orcid":null},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashesh B. Jani","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026088869","display_name":"Walter J. Curran","orcid":"https://orcid.org/0000-0002-7552-4453"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Walter Curran","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024852113","display_name":"Pretesh Patel","orcid":"https://orcid.org/0000-0002-3522-1204"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pretesh Patel","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365664","display_name":"Tian Liu","orcid":"https://orcid.org/0000-0003-1295-7339"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tian Liu","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100619090","display_name":"Xiaofeng Yang","orcid":"https://orcid.org/0000-0001-9023-5855"},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaofeng Yang","raw_affiliation_strings":["The Winship Cancer Institute of Emory Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Winship Cancer Institute of Emory Univ. (United States)","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":null,"apc_paid":null,"fwci":1.0721,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.7569056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"78","last_page":"78"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9896000027656555,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9847000241279602,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.7011608481407166},{"id":"https://openalex.org/keywords/ground-truth","display_name":"Ground truth","score":0.6860414743423462},{"id":"https://openalex.org/keywords/brachytherapy","display_name":"Brachytherapy","score":0.6214956045150757},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5476627349853516},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.47189152240753174},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3950710594654083},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.37720343470573425},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3630937933921814},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2722387909889221},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.18245017528533936},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.12862342596054077}],"concepts":[{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.7011608481407166},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.6860414743423462},{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.6214956045150757},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5476627349853516},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.47189152240753174},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3950710594654083},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.37720343470573425},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3630937933921814},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2722387909889221},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.18245017528533936},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.12862342596054077}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2580802","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2580802","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2021: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2389281101","https://openalex.org/W3107042173","https://openalex.org/W2411709837","https://openalex.org/W4240628612","https://openalex.org/W2994520346","https://openalex.org/W2016426829","https://openalex.org/W2407572472","https://openalex.org/W2413279076","https://openalex.org/W2057864422","https://openalex.org/W2971514792"],"abstract_inverted_index":{"A":[0],"deep-learning":[1],"model":[2,27,47],"based":[3],"on":[4,32,58,208,233,250],"the":[5,15,30,33,38,63,68,91,215,226,247,254,261,268,273,276,289],"U-Net":[6,220],"architecture":[7],"was":[8,43,56,84,203],"developed":[9],"to":[10,28,87,117,241,266],"segment":[11,90],"multiple":[12],"needles":[13,42,93,130,133,181,188,262],"in":[14,25,158,179,253],"3D":[16,59,258],"transrectal":[17],"ultrasound":[18],"(TRUS)":[19],"images.":[20],"Attention":[21],"gates":[22],"were":[23,76,115],"adopted":[24],"our":[26,46,155,176,212,242],"improve":[29],"prediction":[31],"small":[34],"needle":[35,70,106,269],"points.":[36],"Furthermore,":[37],"spatial":[39],"continuity":[40],"of":[41,131,260,278,293],"encoded":[44],"into":[45],"with":[48,62,140,161,182,189,214,219],"total":[49],"variation":[50],"(TV)":[51],"regularization.":[52],"The":[53,81,105,257],"combined":[54],"network":[55,83],"trained":[57,82],"TRUS":[60,98],"patches":[61],"deep":[64,222],"supervision":[65],"strategy,":[66],"where":[67],"binary":[69],"annotation":[71],"images":[72,99],"from":[73,134],"simulation":[74],"CTs":[75],"provided":[77],"as":[78,124],"ground":[79,113,216],"truth.":[80,217],"then":[85],"used":[86,116],"localize":[88],"and":[89,108,121,146,186,221,237,291],"HDR":[92,136,295],"for":[94,173,275],"a":[95,230],"new":[96],"patient":[97],"during":[100],"high-dose-rate":[101],"(HDR)":[102],"prostate":[103,137,255,294],"brachytherapy.":[104,256,296],"shaft":[107,144,153,235],"tip":[109,150,174,209,238],"errors":[110],"against":[111],"CT-based":[112],"truth":[114],"evaluate":[118,267],"other":[119,122],"methods":[120,123],"comparison.":[125],"Our":[126],"method":[127,156,177,228],"detected":[128],"96%":[129,159],"339":[132],"23":[135],"brachytherapy":[138],"patients":[139],"0.29±0.24":[141],"mm":[142,148,165,184,191],"at":[143,149],"error":[145,166,185,192,236],"0.442±0.831":[147],"error.":[151,239],"For":[152],"localization,":[154,175],"resulted":[157,178],"localizations":[160],"less":[162],"than":[163],"0.8":[164],"(needle":[167],"diameter":[168],"is":[169,197,246],"1.67":[170],"mm),":[171],"while":[172],"75%":[180],"0":[183],"21%":[187],"2":[190,198],"(TRUS":[193],"image":[194],"slice":[195],"thickness":[196],"mm).":[199],"No":[200],"significant":[201,231],"difference":[202],"observed":[204],"(p":[205],"=":[206],"0.83)":[207],"localization":[210,252],"between":[211],"results":[213],"Compared":[218],"supervised":[223],"attention":[224],"U-Net,":[225],"proposed":[227],"delivers":[229],"improvement":[232],"both":[234],"Besides,":[240],"best":[243],"knowledge,":[244],"this":[245],"first":[248],"attempt":[249],"multi-needle":[251],"rendering":[259],"could":[263],"help":[264],"clinicians":[265],"placements.":[270],"It":[271],"paves":[272],"way":[274],"development":[277],"real-time":[279],"radiation":[280],"plan":[281],"dose":[282],"assessment":[283],"tools":[284],"that":[285],"can":[286],"further":[287],"elevate":[288],"quality":[290],"outcome":[292]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2025-10-10T00:00:00"}