{"id":"https://openalex.org/W3007842898","doi":"https://doi.org/10.1117/12.2550006","title":"Automatic measurement of extra-axial CSF from infant MRI data","display_name":"Automatic measurement of extra-axial CSF from infant MRI data","publication_year":2020,"publication_date":"2020-02-28","ids":{"openalex":"https://openalex.org/W3007842898","doi":"https://doi.org/10.1117/12.2550006","mag":"3007842898","pmid":"https://pubmed.ncbi.nlm.nih.gov/32728309"},"language":"en","primary_location":{"id":"doi:10.1117/12.2550006","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2550006","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7388182","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016286927","display_name":"Arthur Le Maout","orcid":null},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arthur Le Maout","raw_affiliation_strings":["Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046398473","display_name":"Han Bit Yoon","orcid":null},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Han Bit Yoon","raw_affiliation_strings":["Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":[]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109042640","display_name":"SunHyung Kim","orcid":null},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"SunHyung Kim","raw_affiliation_strings":["Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":[]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079299310","display_name":"Mahmoud Mostapha","orcid":"https://orcid.org/0000-0001-6019-1492"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahmoud Mostapha","raw_affiliation_strings":["Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":[]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041849919","display_name":"Mark D. Shen","orcid":"https://orcid.org/0000-0002-1190-7981"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Shen","raw_affiliation_strings":["Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101841407","display_name":"Juan Carlos Prieto","orcid":"https://orcid.org/0000-0002-3778-9098"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan C. Prieto","raw_affiliation_strings":["Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065838160","display_name":"Martin Styner","orcid":"https://orcid.org/0000-0002-8747-5118"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin A. Styner","raw_affiliation_strings":["Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","The Univ. of North Carolina at Chapel Hill (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"The Univ. of North Carolina at Chapel Hill (United States)","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5016286927"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":null,"apc_paid":null,"fwci":0.1033,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.37392087,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"11317","issue":null,"first_page":"54","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.8121218681335449},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"Cerebrospinal fluid","score":0.7515153288841248},{"id":"https://openalex.org/keywords/subarachnoid-space","display_name":"Subarachnoid space","score":0.7170925140380859},{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.6238073110580444},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5658976435661316},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.5280728340148926},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.43362587690353394},{"id":"https://openalex.org/keywords/graphical-user-interface","display_name":"Graphical user interface","score":0.43160057067871094},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.4058421552181244},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37929779291152954},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.32808464765548706},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.325724720954895},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.27531689405441284},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.17612901329994202},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.11795607209205627},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.10272681713104248}],"concepts":[{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.8121218681335449},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.7515153288841248},{"id":"https://openalex.org/C2780813603","wikidata":"https://www.wikidata.org/wiki/Q268930","display_name":"Subarachnoid space","level":3,"score":0.7170925140380859},{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.6238073110580444},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5658976435661316},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5280728340148926},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.43362587690353394},{"id":"https://openalex.org/C37789001","wikidata":"https://www.wikidata.org/wiki/Q782543","display_name":"Graphical user interface","level":2,"score":0.43160057067871094},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4058421552181244},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37929779291152954},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.32808464765548706},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.325724720954895},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27531689405441284},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.17612901329994202},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.11795607209205627},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.10272681713104248}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2550006","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2550006","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging","raw_type":"proceedings-article"},{"id":"pmid:32728309","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32728309","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7388182","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7388182","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7388182","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7388182","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W2116471897","https://openalex.org/W2116895317","https://openalex.org/W2136145485","https://openalex.org/W2594744452","https://openalex.org/W2754777562","https://openalex.org/W2794317529","https://openalex.org/W2892937277","https://openalex.org/W2895939677"],"related_works":["https://openalex.org/W2415383105","https://openalex.org/W4293097560","https://openalex.org/W2764334540","https://openalex.org/W2045401688","https://openalex.org/W1972670736","https://openalex.org/W4214811308","https://openalex.org/W1543460188","https://openalex.org/W2470064111","https://openalex.org/W2523201464","https://openalex.org/W2970350427"],"abstract_inverted_index":{"The":[0],"quantification":[1],"of":[2,42,90,109,121,143,151,162,176],"cerebrospinal":[3],"fluid":[4,23],"(CSF)":[5],"in":[6,17,30,59,67,88,118,189,193,199],"the":[7,31,39,68,84,91,107,141,160,173],"human":[8],"brain":[9,20,203],"has":[10],"shown":[11],"to":[12,104,139,185,195],"play":[13],"an":[14],"important":[15],"role":[16,198],"early":[18,40],"postnatal":[19],"development.":[21,204],"Extra-axial":[22],"(EA-CSF),":[24],"which":[25],"is":[26,34,64,137],"characterized":[27],"by":[28,101],"CSF":[29,57,62,86,145,179,188],"subarachnoid":[32],"space,":[33],"a":[35,114,119,132,148,163],"promising":[36],"marker":[37],"for":[38,46,128,172],"detection":[41],"children":[43],"at":[44],"risk":[45],"neurodevelopmental":[47],"disorders,":[48],"such":[49,73,177],"as":[50,74],"Autism":[51],"Spectrum":[52],"Disorder":[53],"(ASD).":[54],"Yet,":[55],"non-ventricular":[56],"quantification,":[58,63],"particular":[60],"extra-axial":[61,85,144,178,187],"not":[65],"supported":[66],"major":[69],"neuro-imaging":[70],"software":[71,168],"solutions,":[72],"FreeSurfer.":[75],"Most":[76],"current":[77],"structural":[78],"image":[79],"analysis":[80],"packages":[81],"mask":[82],"out":[83],"space":[87],"one":[89],"first":[92],"pre-processing":[93],"steps.":[94],"A":[95],"quantitative":[96],"protocol":[97],"was":[98],"previously":[99],"developed":[100],"our":[102,129],"group":[103],"objectively":[105],"measure":[106],"volume":[108,112,146],"total":[110],"EA-CSF":[111],"using":[113],"pipeline":[115],"workflow":[116],"implemented":[117],"series":[120],"python":[122],"scripts.":[123],"While":[124],"this":[125],"solution":[126],"worked":[127],"specific":[130],"lab,":[131],"graphical":[133],"user":[134],"interface-based":[135],"tool":[136],"necessary":[138],"facilitate":[140],"computation":[142,175],"across":[147],"wide":[149],"array":[150],"neuroimaging":[152,183,191],"studies":[153,192],"and":[154,201],"research":[155],"labs.":[156],"This":[157],"paper":[158],"presents":[159],"development":[161],"novel":[164],"open-source,":[165],"cross-platform,":[166],"user-friendly":[167],"tool,":[169],"called":[170],"Auto-EACSF,":[171],"automatic":[174],"volume.":[180],"Auto-EACSF":[181],"allows":[182],"labs":[184],"quantify":[186],"their":[190],"order":[194],"investigate":[196],"its":[197],"normal":[200],"atypical":[202]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}