{"id":"https://openalex.org/W3012506502","doi":"https://doi.org/10.1117/12.2549585","title":"Automated breast cancer risk estimation on routine CT thorax scans by deep learning segmentation","display_name":"Automated breast cancer risk estimation on routine CT thorax scans by deep learning segmentation","publication_year":2020,"publication_date":"2020-03-16","ids":{"openalex":"https://openalex.org/W3012506502","doi":"https://doi.org/10.1117/12.2549585","mag":"3012506502"},"language":"en","primary_location":{"id":"doi:10.1117/12.2549585","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2549585","pdf_url":null,"source":{"id":"https://openalex.org/S4306519512","display_name":"Medical Imaging 2020: Computer-Aided Diagnosis","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2020: Computer-Aided Diagnosis","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://lirias.kuleuven.be/bitstream/123456789/653805/2/4511.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060532491","display_name":"Stijn De Buck","orcid":"https://orcid.org/0000-0003-1266-6320"},"institutions":[{"id":"https://openalex.org/I2800231306","display_name":"Universitair Ziekenhuis Leuven","ror":"https://ror.org/0424bsv16","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2800231306"]},{"id":"https://openalex.org/I4210115377","display_name":"VIB-KU Leuven Center for Microbiology","ror":"https://ror.org/02bpp8r91","country_code":"BE","type":"facility","lineage":["https://openalex.org/I2802017950","https://openalex.org/I4210115377","https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Stijn De Buck","raw_affiliation_strings":["KU Leuven (Belgium)","UZ Leuven (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"KU Leuven (Belgium)","institution_ids":["https://openalex.org/I4210115377"]},{"raw_affiliation_string":"UZ Leuven (Belgium)","institution_ids":["https://openalex.org/I2800231306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035292977","display_name":"Jeroen Bertels","orcid":"https://orcid.org/0000-0001-7206-2671"},"institutions":[{"id":"https://openalex.org/I4210115377","display_name":"VIB-KU Leuven Center for Microbiology","ror":"https://ror.org/02bpp8r91","country_code":"BE","type":"facility","lineage":["https://openalex.org/I2802017950","https://openalex.org/I4210115377","https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jeroen Bertels","raw_affiliation_strings":["KU Leuven (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"KU Leuven (Belgium)","institution_ids":["https://openalex.org/I4210115377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073192638","display_name":"Chelsey Vanbilsen","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148648","display_name":"Ziekenhuis Oost-Limburg","ror":"https://ror.org/04fg7az81","country_code":"BE","type":"funder","lineage":["https://openalex.org/I4210148648"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Chelsey Vanbilsen","raw_affiliation_strings":["Ziekenhuis Oost-Limburg (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ziekenhuis Oost-Limburg (Belgium)","institution_ids":["https://openalex.org/I4210148648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083536379","display_name":"Tanguy Dewaele","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tanguy Dewaele","raw_affiliation_strings":["ZOL (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ZOL (Belgium)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075781598","display_name":"Chantal Van Ongeval","orcid":"https://orcid.org/0000-0002-3787-4049"},"institutions":[{"id":"https://openalex.org/I2800231306","display_name":"Universitair Ziekenhuis Leuven","ror":"https://ror.org/0424bsv16","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2800231306"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Chantal Van Ongeval","raw_affiliation_strings":["UZ Leuven (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UZ Leuven (Belgium)","institution_ids":["https://openalex.org/I2800231306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064936871","display_name":"Hilde Bosmans","orcid":"https://orcid.org/0000-0002-9694-510X"},"institutions":[{"id":"https://openalex.org/I2800231306","display_name":"Universitair Ziekenhuis Leuven","ror":"https://ror.org/0424bsv16","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2800231306"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Hilde Bosmans","raw_affiliation_strings":["UZ Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UZ Leuven, Belgium","institution_ids":["https://openalex.org/I2800231306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034216173","display_name":"Jan Vandevenne","orcid":"https://orcid.org/0000-0002-5777-9903"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan Vandevenne","raw_affiliation_strings":["ZOL (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ZOL (Belgium)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017232974","display_name":"Paul Suetens","orcid":"https://orcid.org/0000-0003-1301-0884"},"institutions":[{"id":"https://openalex.org/I4210115377","display_name":"VIB-KU Leuven Center for Microbiology","ror":"https://ror.org/02bpp8r91","country_code":"BE","type":"facility","lineage":["https://openalex.org/I2802017950","https://openalex.org/I4210115377","https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Paul Suetens","raw_affiliation_strings":["KU Leuven (Belgium)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"KU Leuven (Belgium)","institution_ids":["https://openalex.org/I4210115377"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1354,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.53116749,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"72","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11361","display_name":"Digital Radiography and Breast Imaging","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.7629194855690002},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7331454157829285},{"id":"https://openalex.org/keywords/mammography","display_name":"Mammography","score":0.6109448075294495},{"id":"https://openalex.org/keywords/thorax","display_name":"Thorax (insect anatomy)","score":0.6072899699211121},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5460309386253357},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.5165216326713562},{"id":"https://openalex.org/keywords/dice","display_name":"Dice","score":0.49180081486701965},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.47959887981414795},{"id":"https://openalex.org/keywords/ground-truth","display_name":"Ground truth","score":0.46541523933410645},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43987399339675903},{"id":"https://openalex.org/keywords/workload","display_name":"Workload","score":0.41708552837371826},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3124288022518158},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1228591799736023},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.10364440083503723},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.09186059236526489}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7629194855690002},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7331454157829285},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.6109448075294495},{"id":"https://openalex.org/C97834683","wikidata":"https://www.wikidata.org/wiki/Q942508","display_name":"Thorax (insect anatomy)","level":2,"score":0.6072899699211121},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5460309386253357},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5165216326713562},{"id":"https://openalex.org/C22029948","wikidata":"https://www.wikidata.org/wiki/Q45089","display_name":"Dice","level":2,"score":0.49180081486701965},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47959887981414795},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.46541523933410645},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43987399339675903},{"id":"https://openalex.org/C2778476105","wikidata":"https://www.wikidata.org/wiki/Q628539","display_name":"Workload","level":2,"score":0.41708552837371826},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3124288022518158},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1228591799736023},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.10364440083503723},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09186059236526489},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1117/12.2549585","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2549585","pdf_url":null,"source":{"id":"https://openalex.org/S4306519512","display_name":"Medical Imaging 2020: Computer-Aided Diagnosis","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2020: Computer-Aided Diagnosis","raw_type":"proceedings-article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:123456789/653805","is_oa":true,"landing_page_url":"https://lirias.kuleuven.be/bitstream/123456789/653805/2/4511.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"SPIE medical imaging conference 2020: Computer-aided diagnosis, Houston, Texas, USA, 15-20 February 2020","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:lirias2repo.kuleuven.be:123456789/653805","is_oa":true,"landing_page_url":"https://lirias.kuleuven.be/bitstream/123456789/653805/2/4511.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"SPIE medical imaging conference 2020: Computer-aided diagnosis, Houston, Texas, USA, 15-20 February 2020","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7599999904632568,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1522301498","https://openalex.org/W1641498739","https://openalex.org/W1901129140","https://openalex.org/W2009370455","https://openalex.org/W2069144470","https://openalex.org/W2122927109","https://openalex.org/W2125066552","https://openalex.org/W2301358467","https://openalex.org/W2310676712","https://openalex.org/W2464708700","https://openalex.org/W2502312327","https://openalex.org/W2522083379","https://openalex.org/W2592740045","https://openalex.org/W2782323549","https://openalex.org/W4243339308","https://openalex.org/W4302355970"],"related_works":["https://openalex.org/W3104750253","https://openalex.org/W3021239166","https://openalex.org/W2586273397","https://openalex.org/W2390936256","https://openalex.org/W2483429559","https://openalex.org/W2016385589","https://openalex.org/W2009559548","https://openalex.org/W2890643743","https://openalex.org/W4366341510","https://openalex.org/W2906397153"],"abstract_inverted_index":{"Automation":[0],"of":[1,4,46],"systematic":[2],"scoring":[3],"breast":[5,24,38,47,54,89],"glandularity":[6,48],"on":[7,50,73],"CT":[8,41],"thorax":[9,42],"examinations":[10,43],"performed":[11],"for":[12,97],"another":[13],"clinical":[14],"reason":[15],"could":[16],"aid":[17],"in":[18],"detecting":[19],"postmenopausal":[20],"women":[21],"with":[22,44,78,93],"increased":[23],"cancer":[25,90],"risk.":[26],"We":[27],"propose":[28],"a":[29],"novel":[30],"method":[31,85],"that":[32],"combines":[33],"automated":[34],"deep":[35],"learning":[36],"based":[37,49],"segmentation":[39,57],"from":[40],"computation":[45],"radiodensity":[51],"and":[52,77],"volumetric":[53],"density.":[55],"Reasonable":[56],"Dice":[58],"scores":[59],"were":[60],"found":[61],"as":[62,64],"well":[63],"very":[65],"strong":[66],"correlation":[67],"between":[68],"the":[69,74,79,83,98],"risk":[70,91],"measures":[71,92],"computed":[72],"ground":[75],"truth":[76],"proposed":[80,84],"approach.":[81],"Hence,":[82],"can":[86],"offer":[87],"reliable":[88],"limited":[94],"additional":[95],"workload":[96],"radiologist.":[99]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}