{"id":"https://openalex.org/W2922478190","doi":"https://doi.org/10.1117/12.2512875","title":"Mechanically assisted 3D ultrasound with geometrically variable imaging for minimally invasive focal liver tumor therapy","display_name":"Mechanically assisted 3D ultrasound with geometrically variable imaging for minimally invasive focal liver tumor therapy","publication_year":2019,"publication_date":"2019-03-08","ids":{"openalex":"https://openalex.org/W2922478190","doi":"https://doi.org/10.1117/12.2512875","mag":"2922478190"},"language":"en","primary_location":{"id":"doi:10.1117/12.2512875","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2512875","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071830419","display_name":"Derek J. Gillies","orcid":"https://orcid.org/0000-0003-1895-5019"},"institutions":[{"id":"https://openalex.org/I4210105758","display_name":"Robarts Clinical Trials","ror":"https://ror.org/01e36dv41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4210105758","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Derek J. Gillies","raw_affiliation_strings":["Robarts Research Institute (Canada)","Western Univ. (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute (Canada)","institution_ids":["https://openalex.org/I4210105758"]},{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110079327","display_name":"Jeffrey Bax","orcid":null},"institutions":[{"id":"https://openalex.org/I4210105758","display_name":"Robarts Clinical Trials","ror":"https://ror.org/01e36dv41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4210105758","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jeffrey Bax","raw_affiliation_strings":["Robarts Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute (Canada)","institution_ids":["https://openalex.org/I4210105758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058152317","display_name":"Kevin Barker","orcid":null},"institutions":[{"id":"https://openalex.org/I4210105758","display_name":"Robarts Clinical Trials","ror":"https://ror.org/01e36dv41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4210105758","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kevin Barker","raw_affiliation_strings":["Robarts Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute (Canada)","institution_ids":["https://openalex.org/I4210105758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074581536","display_name":"Lori Gardi","orcid":null},"institutions":[{"id":"https://openalex.org/I4210105758","display_name":"Robarts Clinical Trials","ror":"https://ror.org/01e36dv41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4210105758","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Lori Gardi","raw_affiliation_strings":["Robarts Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute (Canada)","institution_ids":["https://openalex.org/I4210105758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066478302","display_name":"David Tessier","orcid":"https://orcid.org/0000-0002-9072-4621"},"institutions":[{"id":"https://openalex.org/I4210105758","display_name":"Robarts Clinical Trials","ror":"https://ror.org/01e36dv41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4210105758","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"David Tessier","raw_affiliation_strings":["Robarts Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute (Canada)","institution_ids":["https://openalex.org/I4210105758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010120469","display_name":"Nirmal Kakani","orcid":null},"institutions":[{"id":"https://openalex.org/I2801926401","display_name":"Manchester Royal Infirmary","ror":"https://ror.org/03kr30n36","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801926401","https://openalex.org/I4210092852"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nirmal Kakani","raw_affiliation_strings":["Manchester Royal Infirmary (United Kingdom)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Royal Infirmary (United Kingdom)","institution_ids":["https://openalex.org/I2801926401"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004966232","display_name":"Aaron Fenster","orcid":"https://orcid.org/0000-0003-3525-2788"},"institutions":[{"id":"https://openalex.org/I4210105758","display_name":"Robarts Clinical Trials","ror":"https://ror.org/01e36dv41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4210105758","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Aaron Fenster","raw_affiliation_strings":["Robarts Research Institute (Canada)","Western Univ. (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute (Canada)","institution_ids":["https://openalex.org/I4210105758"]},{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2688,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.56232956,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"33","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasound-imaging","display_name":"Ultrasound imaging","score":0.6142622232437134},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.5654297471046448},{"id":"https://openalex.org/keywords/ultrasonic-imaging","display_name":"Ultrasonic imaging","score":0.46604123711586},{"id":"https://openalex.org/keywords/3d-ultrasound","display_name":"3D ultrasound","score":0.457923024892807},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.4547835886478424},{"id":"https://openalex.org/keywords/optical-imaging","display_name":"Optical imaging","score":0.4103556275367737},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.37797850370407104},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3683684468269348},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.14255550503730774},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.08986467123031616}],"concepts":[{"id":"https://openalex.org/C2986892559","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasound imaging","level":3,"score":0.6142622232437134},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5654297471046448},{"id":"https://openalex.org/C2989478337","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonic imaging","level":3,"score":0.46604123711586},{"id":"https://openalex.org/C2780170424","wikidata":"https://www.wikidata.org/wiki/Q229399","display_name":"3D ultrasound","level":3,"score":0.457923024892807},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4547835886478424},{"id":"https://openalex.org/C92630104","wikidata":"https://www.wikidata.org/wiki/Q4115103","display_name":"Optical imaging","level":2,"score":0.4103556275367737},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37797850370407104},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3683684468269348},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.14255550503730774},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08986467123031616}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2512875","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2512875","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1980811501","https://openalex.org/W2014683369","https://openalex.org/W2028122120","https://openalex.org/W2085070000","https://openalex.org/W2160201029","https://openalex.org/W2204081699","https://openalex.org/W6637304570","https://openalex.org/W6700734864"],"related_works":["https://openalex.org/W2392518627","https://openalex.org/W4250133764","https://openalex.org/W1972056390","https://openalex.org/W2992379896","https://openalex.org/W2147796458","https://openalex.org/W2391770021","https://openalex.org/W2613177006","https://openalex.org/W2010072608","https://openalex.org/W2314240788","https://openalex.org/W2152230954"],"abstract_inverted_index":{"Liver":[0],"cancer":[1,11,45,67],"is":[2,35,47,87,171,197],"the":[3,58,85,91,99,108,189,192,217,228],"second":[4],"and":[5,16,25,41,46,53,89,118,137,178,184,227,243],"sixth":[6],"most":[7],"frequent":[8],"cause":[9],"of":[10,32,72,98,110,122,143,191],"mortality":[12],"worldwide":[13],"in":[14,22,211],"men":[15],"women,":[17],"respectively,":[18],"with":[19,64,80,140,203],"high":[20,65],"prevalence":[21],"under":[23],"developed":[24],"developing":[26],"countries.":[27],"Minimally":[28],"invasive":[29],"focal":[30],"ablation":[31],"liver":[33],"tumors":[34],"an":[36],"alternative":[37],"technique":[38],"to":[39,93,103,133,164,187,207],"resection":[40],"transplantation":[42],"for":[43,145],"early-stage":[44],"focused":[48],"on":[49,199,237],"reducing":[50],"patient":[51,212],"complications":[52],"recovery":[54],"times.":[55],"Although":[56],"promising,":[57],"therapeutic":[59],"benefits":[60],"are":[61],"currently":[62],"present":[63],"local":[66],"recurrence.":[68],"One":[69],"potential":[70],"source":[71],"error":[73],"arises":[74],"when":[75],"performing":[76],"therapy":[77],"applicator":[78,166],"guidance":[79,119],"2D":[81,157],"ultrasound":[82],"(US)":[83],"since":[84],"field-of-view":[86],"limited":[88],"requires":[90],"physician":[92],"build":[94],"a":[95,111,174,200,238],"mental":[96],"image":[97],"anatomy.":[100],"Our":[101],"solution":[102],"this":[104],"limitation":[105],"has":[106],"been":[107],"development":[109],"novel":[112],"mechanically":[113],"assisted":[114],"3D":[115,147,223],"US":[116,148,158],"imaging":[117],"system":[120],"capable":[121],"providing":[123],"geometrically":[124],"variable":[125,146],"images.":[126],"A":[127],"three-motor":[128],"mechanical":[129,176,195],"mover":[130,151,170],"was":[131],"designed":[132],"provide":[134],"linear,":[135],"tilt,":[136],"hybrid":[138],"geometries":[139],"adjustable":[141,205],"ranges":[142],"motion":[144],"fields-of-view.":[149],"This":[150,169,194,214],"can":[152],"manipulate":[153],"any":[154],"clinically":[155,248],"available":[156],"transducer":[159],"via":[160],"transducer-specific":[161],"3D-printed":[162],"holders":[163],"guide":[165],"insertions":[167],"intraoperatively.":[168],"held":[172],"by":[173],"counterbalanced":[175],"\u201carm":[177],"wrist\u201d,":[179],"which":[180],"contain":[181],"electromagnetic":[182],"brakes":[183],"five":[185],"encoders":[186],"track":[188],"position":[190],"transducer.":[193],"support":[196],"mounted":[198],"portable":[201],"cart":[202],"coarse":[204],"height":[206],"accommodate":[208],"gross":[209],"differences":[210],"sizes.":[213],"work":[215],"represents":[216],"design,":[218],"construction,":[219],"software":[220],"implementation,":[221],"preliminary":[222],"volume":[224],"reconstruction":[225],"evaluation,":[226],"first":[229],"qualitative":[230],"human":[231,244],"volunteer":[232,245],"scans.":[233],"Geometric":[234],"errors":[235],"performed":[236],"grid":[239],"phantom":[240],"were":[241,247],"<3%":[242],"images":[246],"applicable.":[249]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}