{"id":"https://openalex.org/W2921976093","doi":"https://doi.org/10.1117/12.2512873","title":"Modeling normal brain asymmetry in MR images applied to anomaly detection without segmentation and data annotation","display_name":"Modeling normal brain asymmetry in MR images applied to anomaly detection without segmentation and data annotation","publication_year":2019,"publication_date":"2019-03-13","ids":{"openalex":"https://openalex.org/W2921976093","doi":"https://doi.org/10.1117/12.2512873","mag":"2921976093"},"language":"en","primary_location":{"id":"doi:10.1117/12.2512873","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2512873","pdf_url":null,"source":{"id":"https://openalex.org/S4306519510","display_name":"Medical Imaging 2019: Computer-Aided Diagnosis","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2019: Computer-Aided Diagnosis","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046827620","display_name":"Samuel Botter Martins","orcid":"https://orcid.org/0000-0002-2894-3911"},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]},{"id":"https://openalex.org/I107371206","display_name":"Federal Institute of S\u00e3o Paulo","ror":"https://ror.org/005pn5z34","country_code":"BR","type":"education","lineage":["https://openalex.org/I107371206"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Samuel B. Martins","raw_affiliation_strings":["Federal Institute of Education, Science, and Technology of S\u00e3o Paulo (Brazil)","Univ. of Campinas (Brazil)"],"affiliations":[{"raw_affiliation_string":"Federal Institute of Education, Science, and Technology of S\u00e3o Paulo (Brazil)","institution_ids":["https://openalex.org/I107371206"]},{"raw_affiliation_string":"Univ. of Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043224192","display_name":"B\u00e1rbara C. Benato","orcid":"https://orcid.org/0000-0003-0806-3607"},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Barbara C. Benato","raw_affiliation_strings":["Univ. of Campinas (Brazil)"],"affiliations":[{"raw_affiliation_string":"Univ. of Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100546733","display_name":"Bruna Fabiana Monteiro da Silva","orcid":null},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bruna F. Silva","raw_affiliation_strings":["Univ. of Campinas (Brazil)"],"affiliations":[{"raw_affiliation_string":"Univ. of Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080241120","display_name":"Clarissa Lin Yasuda","orcid":"https://orcid.org/0000-0001-9084-7173"},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Clarissa L. Yasuda","raw_affiliation_strings":["Univ. of Campinas (Brazil)"],"affiliations":[{"raw_affiliation_string":"Univ. of Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015267493","display_name":"Alexandre X. Falc\u00e3o","orcid":"https://orcid.org/0000-0002-2914-5380"},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alexandre X. Falc\u00e3o","raw_affiliation_strings":["Univ. of Campinas (Brazil)"],"affiliations":[{"raw_affiliation_string":"Univ. of Campinas (Brazil)","institution_ids":["https://openalex.org/I181391015"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5046827620"],"corresponding_institution_ids":["https://openalex.org/I107371206","https://openalex.org/I181391015"],"apc_list":null,"apc_paid":null,"fwci":0.7297,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.68169924,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"11","issue":null,"first_page":"11","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11512","display_name":"Anomaly Detection Techniques and Applications","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.712979793548584},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6921821236610413},{"id":"https://openalex.org/keywords/anomaly-detection","display_name":"Anomaly detection","score":0.6403565406799316},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6103547811508179},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.544714093208313},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.4727374315261841},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.41747021675109863},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.4158513844013214},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.41466251015663147},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3810366988182068}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.712979793548584},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6921821236610413},{"id":"https://openalex.org/C739882","wikidata":"https://www.wikidata.org/wiki/Q3560506","display_name":"Anomaly detection","level":2,"score":0.6403565406799316},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6103547811508179},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.544714093208313},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.4727374315261841},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.41747021675109863},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.4158513844013214},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.41466251015663147},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3810366988182068}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2512873","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2512873","pdf_url":null,"source":{"id":"https://openalex.org/S4306519510","display_name":"Medical Imaging 2019: Computer-Aided Diagnosis","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2019: Computer-Aided Diagnosis","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life in Land","score":0.5099999904632568,"id":"https://metadata.un.org/sdg/15"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W2004293194","https://openalex.org/W2007071216","https://openalex.org/W2017436068","https://openalex.org/W2025009638","https://openalex.org/W2036109700","https://openalex.org/W2043404871","https://openalex.org/W2100199701","https://openalex.org/W2115284428","https://openalex.org/W2117340355","https://openalex.org/W2131007620","https://openalex.org/W2131904035","https://openalex.org/W2133287637","https://openalex.org/W2143826137","https://openalex.org/W2145094598","https://openalex.org/W2165278596","https://openalex.org/W2169491762","https://openalex.org/W2187089797","https://openalex.org/W2219879775","https://openalex.org/W2476839077","https://openalex.org/W2732036031","https://openalex.org/W2793050634","https://openalex.org/W2997574889","https://openalex.org/W4241074797","https://openalex.org/W6604254268","https://openalex.org/W6679539681","https://openalex.org/W6679997575","https://openalex.org/W6681096077","https://openalex.org/W6734658422"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W2263699433","https://openalex.org/W2377979023","https://openalex.org/W2218034408","https://openalex.org/W2392921965","https://openalex.org/W2358755282","https://openalex.org/W2625833328","https://openalex.org/W1533177136","https://openalex.org/W2251519152","https://openalex.org/W4380994516"],"abstract_inverted_index":{"While":[0],"the":[1,27,49,97,120,124,144,157,161,171,182,193,198],"human":[2],"brain":[3,23,41,83,172],"presents":[4],"natural":[5],"structural":[6,40],"asymmetries":[7],"between":[8],"left":[9],"and":[10,63,85,136,148,173,176,190],"right":[11],"hemispheres":[12],"in":[13,106,167],"MR":[14],"images,":[15,108],"most":[16],"neurological":[17,50],"diseases":[18],"are":[19],"associated":[20],"with":[21,77],"abnormal":[22,107,127,164],"asymmetries.":[24],"Due":[25],"to":[26,37,72,123,159],"great":[28],"variety":[29],"of":[30,48,75,100,126,133,141,170,192,200],"such":[31],"anomalies,":[32],"we":[33],"present":[34],"a":[35,69,86,115,149],"framework":[36,98,162],"model":[38,53,71,95],"normal":[39],"asymmetry":[42,129,165],"from":[43],"control":[44],"subjects":[45],"only,":[46],"independent":[47,99],"disease.":[51],"The":[52,139],"dismisses":[54],"data":[55],"annotation":[56,191],"by":[57],"exploiting":[58],"generative":[59],"deep":[60],"neural":[61],"networks":[62],"one-class":[64,87],"classifiers.":[65],"We":[66,118],"also":[67],"propose":[68],"patch-based":[70],"localize":[73],"volumes":[74],"interest":[76],"reduced":[78],"background":[79],"sizes":[80],"around":[81],"selected":[82],"structures":[84],"classifier":[88],"based":[89,152],"on":[90,153],"an":[91],"optimum-path":[92],"forest.":[93],"This":[94],"makes":[96],"segmentation,":[101],"which":[102],"may":[103,110],"fail,":[104],"especially":[105],"or":[109],"not":[111],"be":[112,185],"available":[113],"for":[114,163,187],"given":[116],"structure.":[117],"validate":[119],"first":[121],"method":[122],"detection":[125,166],"hippocampal":[128],"using":[130,143],"distinct":[131],"groups":[132],"Epilepsy":[134],"patients":[135],"testing":[137],"controls.":[138],"results":[140],"validation":[142],"original":[145],"feature":[146],"space":[147,151],"two-dimensional":[150],"non-linear":[154],"projection":[155],"show":[156],"potential":[158],"extend":[160],"other":[168],"parts":[169],"develop":[174],"intelligent":[175],"interactive":[177],"virtual":[178],"environments.":[179],"For":[180],"instance,":[181],"approach":[183],"can":[184],"used":[186],"screening,":[188],"inspection,":[189],"detected":[194],"anomaly":[195],"type,":[196],"allowing":[197],"development":[199],"CADx":[201],"systems.":[202]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}