{"id":"https://openalex.org/W2921273685","doi":"https://doi.org/10.1117/12.2512119","title":"Cerebellum parcellation with convolutional neural networks","display_name":"Cerebellum parcellation with convolutional neural networks","publication_year":2019,"publication_date":"2019-03-14","ids":{"openalex":"https://openalex.org/W2921273685","doi":"https://doi.org/10.1117/12.2512119","mag":"2921273685","pmid":"https://pubmed.ncbi.nlm.nih.gov/32394999"},"language":"en","primary_location":{"id":"doi:10.1117/12.2512119","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2512119","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2019: Image Processing","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7211767","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070081887","display_name":"Shuo Han","orcid":"https://orcid.org/0000-0003-2033-9004"},"institutions":[{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shuo Han","raw_affiliation_strings":["Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA","Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD 20892, USA","National Institutes of Health (United States)","The Johns Hopkins Univ. School of Medicine (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA","institution_ids":["https://openalex.org/I2799853436","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD 20892, USA","institution_ids":["https://openalex.org/I4210136897","https://openalex.org/I1299303238"]},{"raw_affiliation_string":"National Institutes of Health (United States)","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"The Johns Hopkins Univ. School of Medicine (United States)","institution_ids":["https://openalex.org/I2799853436","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102852563","display_name":"Yufan He","orcid":"https://orcid.org/0000-0003-4095-9104"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yufan He","raw_affiliation_strings":["Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA","Johns Hopkins Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins Univ. (United States)","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075622613","display_name":"Aaron Carass","orcid":"https://orcid.org/0000-0003-4939-5085"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Carass","raw_affiliation_strings":["Department of Computer Science, The Johns Hopkins University, Baltimore, MD 21218, USA","Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA","Johns Hopkins University (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, The Johns Hopkins University, Baltimore, MD 21218, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University (United States)","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113605332","display_name":"Sarah H. Ying","orcid":null},"institutions":[{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah H. Ying","raw_affiliation_strings":["Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA","The Johns Hopkins Univ. School of Medicine (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"The Johns Hopkins Univ. School of Medicine (United States)","institution_ids":["https://openalex.org/I2799853436","https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066682675","display_name":"Jerry L. Prince","orcid":"https://orcid.org/0000-0002-6553-0876"},"institutions":[{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerry L. Prince","raw_affiliation_strings":["Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA","Department of Computer Science, The Johns Hopkins University, Baltimore, MD 21218, USA","Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA","Johns Hopkins Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA","institution_ids":["https://openalex.org/I2799853436","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Department of Computer Science, The Johns Hopkins University, Baltimore, MD 21218, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins Univ. (United States)","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5070081887"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210136897"],"apc_list":null,"apc_paid":null,"fwci":1.5022,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.82329293,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"10949","issue":null,"first_page":"19","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10949","display_name":"Genetic Neurodegenerative Diseases","score":0.9861000180244446,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9797999858856201,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebellum","display_name":"Cerebellum","score":0.8293749094009399},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.649824321269989},{"id":"https://openalex.org/keywords/spinocerebellar-ataxia","display_name":"Spinocerebellar ataxia","score":0.638119637966156},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.614362359046936},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5905453562736511},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5796220898628235},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5434080362319946},{"id":"https://openalex.org/keywords/minimum-bounding-box","display_name":"Minimum bounding box","score":0.5264050364494324},{"id":"https://openalex.org/keywords/cerebellar-ataxia","display_name":"Cerebellar ataxia","score":0.48723092675209045},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.34905433654785156},{"id":"https://openalex.org/keywords/ataxia","display_name":"Ataxia","score":0.25144967436790466},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.1738397777080536},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.13295060396194458}],"concepts":[{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.8293749094009399},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.649824321269989},{"id":"https://openalex.org/C2779500118","wikidata":"https://www.wikidata.org/wiki/Q899726","display_name":"Spinocerebellar ataxia","level":3,"score":0.638119637966156},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.614362359046936},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5905453562736511},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5796220898628235},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5434080362319946},{"id":"https://openalex.org/C147037132","wikidata":"https://www.wikidata.org/wiki/Q6865426","display_name":"Minimum bounding box","level":3,"score":0.5264050364494324},{"id":"https://openalex.org/C2780148635","wikidata":"https://www.wikidata.org/wiki/Q154709","display_name":"Cerebellar ataxia","level":3,"score":0.48723092675209045},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.34905433654785156},{"id":"https://openalex.org/C2780906641","wikidata":"https://www.wikidata.org/wiki/Q213373","display_name":"Ataxia","level":2,"score":0.25144967436790466},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1738397777080536},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.13295060396194458}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2512119","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2512119","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2019: Image Processing","raw_type":"proceedings-article"},{"id":"pmid:32394999","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32394999","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7211767","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7211767","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7211767","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7211767","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1522301498","https://openalex.org/W1794421049","https://openalex.org/W1964113540","https://openalex.org/W2025009638","https://openalex.org/W2117340355","https://openalex.org/W2119800915","https://openalex.org/W2146417264","https://openalex.org/W2302255633","https://openalex.org/W2556879144","https://openalex.org/W2563357898","https://openalex.org/W2572730214","https://openalex.org/W2703616258","https://openalex.org/W2734349601","https://openalex.org/W2737485754","https://openalex.org/W2784226479","https://openalex.org/W2806070179","https://openalex.org/W3104370314","https://openalex.org/W4295245474","https://openalex.org/W6631190155","https://openalex.org/W6631782140","https://openalex.org/W6698183232","https://openalex.org/W6730824639","https://openalex.org/W6732751041","https://openalex.org/W6735463952"],"related_works":["https://openalex.org/W2913492084","https://openalex.org/W2132539907","https://openalex.org/W2126437655","https://openalex.org/W2353724751","https://openalex.org/W4318751391","https://openalex.org/W4390398949","https://openalex.org/W4389441190","https://openalex.org/W2033545352","https://openalex.org/W2034743776","https://openalex.org/W2047991365"],"abstract_inverted_index":{"To":[0],"better":[1],"understand":[2],"cerebellum-related":[3],"diseases":[4],"and":[5,27,46,91,187,191],"functional":[6,57],"mapping":[7],"of":[8,13,43,49,152,183,197],"the":[9,64,111,128,138,141,145,166],"cerebellum,":[10],"quantitative":[11],"measurements":[12],"cerebellar":[14,44,51],"regions":[15,52],"in":[16,24,93],"magnetic":[17],"resonance":[18],"(MR)":[19],"images":[20,156,182],"have":[21,32,40,84,88],"been":[22,71,85],"studied":[23],"both":[25],"clinical":[26],"neurological":[28],"studies.":[29],"Such":[30],"studies":[31],"revealed":[33],"that":[34,47],"different":[35,41,50],"spinocerebellar":[36],"ataxia":[37],"(SCA)":[38],"subtypes":[39],"patterns":[42],"atrophy":[45,48],"is":[53,200],"correlated":[54],"with":[55,160,189],"specific":[56],"losses.":[58],"Previous":[59],"methods":[60],"to":[61,67,87,109,122,136,179],"automatically":[62],"parcellate":[63,110,137],"cerebellum-that":[65],"is,":[66],"identify":[68],"its":[69],"sub-regions-have":[70],"largely":[72],"based":[73],"on":[74],"multi-atlas":[75],"segmentation.":[76],"Recently,":[77],"deep":[78],"convolutional":[79],"neural":[80],"network":[81,119,133],"(CNN)":[82],"algorithms":[83],"shown":[86],"high":[89],"speed":[90],"accuracy":[92],"cerebral":[94],"sub-cortical":[95],"structure":[96],"segmentation":[97],"from":[98],"MR":[99,181],"images.":[100],"In":[101],"this":[102,198],"work,":[103],"two":[104],"three-dimensional":[105],"CNNs":[106],"were":[107],"used":[108,121,135],"cerebellum":[112,139],"into":[113],"28":[114],"regions.":[115],"First,":[116],"a":[117,124,131,161,184],"locating":[118],"was":[120,134,157,176],"predict":[123],"bounding":[125,146],"box":[126],"around":[127],"cerebellum.":[129],"Second,":[130],"parcellating":[132],"using":[140],"entire":[142],"region":[143],"within":[144],"box.":[147],"A":[148,194],"leave-one-out":[149],"cross":[150],"validation":[151],"fifteen":[153],"manually":[154],"delineated":[155],"performed.":[158],"Compared":[159],"previously":[162],"reported":[163],"state-of-the-art":[164],"algorithm,":[165],"proposed":[167,174],"algorithm":[168,175,199],"shows":[169],"superior":[170],"Dice":[171],"coefficients.":[172],"The":[173],"further":[177],"applied":[178],"three":[180],"healthy":[185],"subject":[186],"subjects":[188],"SCA6":[190],"SCA8,":[192],"respectively.":[193],"Singularity":[195],"container":[196],"publicly":[201],"available.":[202]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}
