{"id":"https://openalex.org/W2792624137","doi":"https://doi.org/10.1117/12.2293120","title":"CT-ultrasound deformable registration for PET-determined prostate brachytherapy","display_name":"CT-ultrasound deformable registration for PET-determined prostate brachytherapy","publication_year":2018,"publication_date":"2018-03-13","ids":{"openalex":"https://openalex.org/W2792624137","doi":"https://doi.org/10.1117/12.2293120","mag":"2792624137","pmid":"https://pubmed.ncbi.nlm.nih.gov/41069789"},"language":"en","primary_location":{"id":"doi:10.1117/12.2293120","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2293120","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12505220/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100626273","display_name":"Junghoon Lee","orcid":"https://orcid.org/0000-0002-3004-8625"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junghoon Lee","raw_affiliation_strings":["Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD, USA","Johns Hopkins Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins Univ. (United States)","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054386630","display_name":"Daniel Y. Song","orcid":"https://orcid.org/0000-0002-3495-8677"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Y. Song","raw_affiliation_strings":["Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD, USA","Johns Hopkins Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins Univ. (United States)","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":null,"apc_paid":null,"fwci":1.574,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.84693878,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"62","issue":null,"first_page":"99","last_page":"99"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brachytherapy","display_name":"Brachytherapy","score":0.687104344367981},{"id":"https://openalex.org/keywords/image-registration","display_name":"Image registration","score":0.5445632338523865},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.5258553624153137},{"id":"https://openalex.org/keywords/medical-physics","display_name":"Medical physics","score":0.4765791893005371},{"id":"https://openalex.org/keywords/prostate-brachytherapy","display_name":"Prostate brachytherapy","score":0.47182947397232056},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.453948974609375},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.43389853835105896},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3956510126590729},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37402474880218506},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.36064231395721436},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.344952255487442},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.17211028933525085}],"concepts":[{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.687104344367981},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.5445632338523865},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5258553624153137},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.4765791893005371},{"id":"https://openalex.org/C2778648096","wikidata":"https://www.wikidata.org/wiki/Q17009878","display_name":"Prostate brachytherapy","level":4,"score":0.47182947397232056},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.453948974609375},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.43389853835105896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3956510126590729},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37402474880218506},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.36064231395721436},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.344952255487442},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.17211028933525085},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1117/12.2293120","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2293120","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling","raw_type":"proceedings-article"},{"id":"pmid:41069789","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41069789","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:europepmc.org:11313209","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12505220","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12505220","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12505220/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12505220","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12505220/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6899999976158142}],"awards":[{"id":"https://openalex.org/G99840766","display_name":null,"funder_award_id":"R01 CA151395","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1906917243","https://openalex.org/W1978202284","https://openalex.org/W1994463565","https://openalex.org/W2016979826","https://openalex.org/W2023904385","https://openalex.org/W2031228941","https://openalex.org/W2084642980","https://openalex.org/W2125700054","https://openalex.org/W2128082955","https://openalex.org/W2143808155","https://openalex.org/W2230026600","https://openalex.org/W2345625043","https://openalex.org/W2715024955","https://openalex.org/W2764597687","https://openalex.org/W2915478882","https://openalex.org/W6745526252","https://openalex.org/W6759589072"],"related_works":["https://openalex.org/W1968581313","https://openalex.org/W2810663015","https://openalex.org/W2102373670","https://openalex.org/W2809967836","https://openalex.org/W2106662487","https://openalex.org/W2985431943","https://openalex.org/W2807466365","https://openalex.org/W1965484281","https://openalex.org/W2460936463","https://openalex.org/W4213032456"],"abstract_inverted_index":{"Recent":[0],"advances":[1],"in":[2,40,181],"positron":[3],"emission":[4],"tomography":[5],"(PET)":[6],"targeting":[7],"prostate":[8,60,112,129,143,176],"specific":[9,15],"membrane":[10],"antigen":[11],"(PSMA)":[12],"allow":[13],"highly":[14],"and":[16,26,66,145,160,186],"sensitive":[17],"identification":[18],"of":[19,23,38,57,74],"intra/extraprostatic":[20],"tumors.":[21],"Combination":[22],"PSMA":[24,75],"PET":[25,76],"intraoperative":[27,67,78,183],"transrectal":[28],"ultrasound":[29],"(TRUS)":[30],"images":[31],"enables":[32,72],"to":[33,45,50,77,116,137],"further":[34],"improve":[35],"the":[36,43,48,51,63,111,117,128,135,138,142,148,199,203],"standard":[37],"care":[39],"brachytherapy,":[41],"allowing":[42],"physician":[44],"precisely":[46],"tailor":[47],"dose":[49],"individual's":[52],"tumor.":[53],"The":[54,101,114,165],"key":[55],"step":[56],"PET-determined":[58],"focal":[59],"brachytherapy":[61,177],"is":[62,103,212],"preoperative":[64],"PET/CT":[65],"TRUS":[68,185],"image":[69,87,92],"fusion,":[70],"which":[71,182,211],"mapping":[73],"imaging.":[79],"In":[80],"this":[81],"paper,":[82],"we":[83],"propose":[84],"a":[85,96,121,157],"deformable":[86,163],"registration":[88,169,194],"algorithm":[89,170],"for":[90,162],"PET/CT-TRUS":[91],"fusion":[93],"based":[94,109],"on":[95,110,174,209],"structural":[97,158],"descriptor":[98,159],"map":[99],"(SDM).":[100],"SDM":[102],"computed":[104,149,196],"by":[105,197],"solving":[106],"Laplace's":[107,118],"equation":[108,119],"segmentations.":[113],"solution":[115],"with":[120],"boundary":[122,139],"condition":[123],"provides":[124],"equipotential":[125,150],"surfaces":[126],"within":[127],"that":[130],"describe":[131],"smooth":[132],"transitions":[133],"from":[134],"midline":[136],"while":[140],"preserving":[141],"shape":[144],"geometry.":[146],"Therefore,":[147],"surface":[151],"distribution":[152],"can":[153],"be":[154],"considered":[155],"as":[156,202],"used":[161],"registration.":[164],"proposed":[166],"SDM-based":[167],"CT-TRUS":[168],"has":[171],"been":[172],"evaluated":[173],"five":[175],"patient":[178],"data":[179],"sets":[180],"end-of-implantation":[184],"day":[187],"1":[188],"post-implant":[189],"CT":[190],"were":[191,206],"registered.":[192],"Target":[193],"errors":[195],"using":[198],"implanted":[200],"seeds":[201],"anatomical":[204],"landmarks":[205],"2.25\u00b11.36":[207],"mm":[208],"average,":[210],"clinically":[213],"acceptable.":[214]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}