{"id":"https://openalex.org/W2591670776","doi":"https://doi.org/10.1117/12.2255696","title":"Deep learning for segmentation of brain tumors: can we train with images from different institutions?","display_name":"Deep learning for segmentation of brain tumors: can we train with images from different institutions?","publication_year":2017,"publication_date":"2017-03-03","ids":{"openalex":"https://openalex.org/W2591670776","doi":"https://doi.org/10.1117/12.2255696","mag":"2591670776"},"language":"en","primary_location":{"id":"doi:10.1117/12.2255696","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2255696","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059482225","display_name":"David Paredes","orcid":"https://orcid.org/0000-0001-9740-4439"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David Paredes","raw_affiliation_strings":["Duke Univ. School of Medicine (United States)","Carl E. Ravin Advanced Imaging Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Duke Univ. School of Medicine (United States)","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Carl E. Ravin Advanced Imaging Labs. (United States)","institution_ids":["https://openalex.org/I4210145671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054599006","display_name":"Ashirbani Saha","orcid":"https://orcid.org/0000-0002-7650-1720"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashirbani Saha","raw_affiliation_strings":["Duke Univ. School of Medicine (United States)","Carl E. Ravin Advanced Imaging Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Duke Univ. School of Medicine (United States)","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Carl E. Ravin Advanced Imaging Labs. (United States)","institution_ids":["https://openalex.org/I4210145671"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001300575","display_name":"Maciej A. Mazurowski","orcid":"https://orcid.org/0000-0003-4202-8602"},"institutions":[{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maciej A. Mazurowski","raw_affiliation_strings":["Duke Univ. School of Medicine (United States)","Carl E. Ravin Advanced Imaging Labs. (United States)","Duke Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Duke Univ. School of Medicine (United States)","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Carl E. Ravin Advanced Imaging Labs. (United States)","institution_ids":["https://openalex.org/I4210145671"]},{"raw_affiliation_string":"Duke Univ. (United States)","institution_ids":["https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5059482225"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210145671"],"apc_list":null,"apc_paid":null,"fwci":0.4843,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.68074126,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"10134","issue":null,"first_page":"101341P","last_page":"101341P"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8577979803085327},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6616195440292358},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6368612051010132},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5825816988945007},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5451624989509583},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5007131099700928}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8577979803085327},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6616195440292358},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6368612051010132},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5825816988945007},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5451624989509583},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5007131099700928}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2255696","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2255696","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1865761","https://openalex.org/W1597605992","https://openalex.org/W1641498739","https://openalex.org/W1797360365","https://openalex.org/W1884191083","https://openalex.org/W2020044743","https://openalex.org/W2025987593","https://openalex.org/W2037316890","https://openalex.org/W2093758653","https://openalex.org/W2128739912","https://openalex.org/W2133467637","https://openalex.org/W2138055191","https://openalex.org/W2310992461","https://openalex.org/W2474982400","https://openalex.org/W2919115771","https://openalex.org/W2953066166","https://openalex.org/W6638176760","https://openalex.org/W6639540389","https://openalex.org/W6665643899","https://openalex.org/W6720861437","https://openalex.org/W6764750447"],"related_works":["https://openalex.org/W2731899572","https://openalex.org/W3215138031","https://openalex.org/W2755342338","https://openalex.org/W2058170566","https://openalex.org/W2036807459","https://openalex.org/W2775347418","https://openalex.org/W1969923398","https://openalex.org/W2166024367","https://openalex.org/W2772917594","https://openalex.org/W3009238340"],"abstract_inverted_index":{"Deep":[0],"learning":[1],"and":[2,15,43,65,108,134,148,193,218],"convolutional":[3],"neural":[4],"networks":[5],"(CNNs)":[6],"in":[7,37,97,157,187,246],"particular":[8],"are":[9],"increasingly":[10],"popular":[11],"tools":[12],"for":[13,26,93,132,189,194,235],"segmentation":[14,27,70],"classification":[16],"of":[17,28,45,72,89,106,116,136,237],"medical":[18],"images.":[19],"CNNs":[20],"were":[21],"shown":[22],"to":[23,177,203,207,211,215,220],"be":[24,233,241],"successful":[25],"brain":[29],"tumors":[30],"into":[31],"multiple":[32,111],"regions":[33],"or":[34],"labels.":[35],"However,":[36],"the":[38,69,73,117,119,126,137,146,165,182,190,199],"environment":[39],"which":[40],"fosters":[41],"data-sharing":[42],"collection":[44],"multi-institutional":[46],"datasets,":[47],"a":[48,104,155,172,244],"question":[49],"arises:":[50],"does":[51],"training":[52,107,133,147,178],"with":[53,58,169,179,243],"data":[54,79,88,124,170,180,229],"from":[55,125,171,181],"another":[56,143],"institution":[57,128,174],"potentially":[59],"different":[60,173,196],"imaging":[61],"equipment,":[62],"contrast":[63],"protocol,":[64],"patient":[66],"population":[67],"impact":[68],"performance":[71,158,188],"CNN?":[74],"Our":[75],"study":[76],"presents":[77],"preliminary":[78],"towards":[80],"answering":[81],"this":[82,239],"question.":[83],"Specifically,":[84],"we":[85,225],"used":[86,131,234],"MRI":[87],"glioblastoma":[90],"(GBM)":[91],"patients":[92],"two":[94],"institutions":[95,231],"present":[96],"The":[98,185],"Cancer":[99],"Imaging":[100],"Archive.":[101],"We":[102,153],"performed":[103],"process":[105],"testing":[109,149],"CNN":[110,120,166],"times":[112],"such":[113],"that":[114,129,227],"half":[115,135],"time":[118,138],"was":[121,130,140,167],"tested":[122,141],"on":[123,142],"same":[127,183],"it":[139],"institution,":[144],"keeping":[145],"set":[150],"size":[151],"constant.":[152],"observed":[154],"decrease":[156,245],"as":[159,175],"measured":[160],"by":[161],"Dice":[162],"coefficient":[163],"when":[164],"trained":[168],"compared":[176],"institution.":[184],"changes":[186],"entire":[191],"tumor":[192,200],"four":[195],"labels":[197],"within":[198],"were:":[201],"0.72":[202],"0.65":[204],"(p=0.06),":[205],"0.61":[206],"0.58":[208],"(p=0.49),":[209],"0.54":[210],"0.51":[212],"(p=0.82),":[213],"0.31":[214],"0.24":[216],"(p<0.03),":[217],"0.43":[219],"0.31(p<0.003)":[221],"respectively.":[222],"In":[223],"summary,":[224],"found":[226],"while":[228],"across":[230],"can":[232],"development":[236],"CNNs,":[238],"might":[240],"associated":[242],"performance.":[247]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}