{"id":"https://openalex.org/W2594127790","doi":"https://doi.org/10.1117/12.2254147","title":"Multi-atlas segmentation enables robust multi-contrast MRI spleen segmentation for splenomegaly","display_name":"Multi-atlas segmentation enables robust multi-contrast MRI spleen segmentation for splenomegaly","publication_year":2017,"publication_date":"2017-02-24","ids":{"openalex":"https://openalex.org/W2594127790","doi":"https://doi.org/10.1117/12.2254147","mag":"2594127790","pmid":"https://pubmed.ncbi.nlm.nih.gov/28649156"},"language":"en","primary_location":{"id":"doi:10.1117/12.2254147","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2254147","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067191302","display_name":"Yuankai Huo","orcid":"https://orcid.org/0000-0002-2096-8065"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yuankai Huo","raw_affiliation_strings":["Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100390349","display_name":"Jiaqi Liu","orcid":"https://orcid.org/0000-0001-5595-5988"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiaqi Liu","raw_affiliation_strings":["Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004320806","display_name":"Zhoubing Xu","orcid":"https://orcid.org/0000-0002-8777-0977"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhoubing Xu","raw_affiliation_strings":["Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067051961","display_name":"Robert L. Harrigan","orcid":"https://orcid.org/0000-0001-7894-1642"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert L. Harrigan","raw_affiliation_strings":["Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109421874","display_name":"Albert Assad","orcid":null},"institutions":[{"id":"https://openalex.org/I924451375","display_name":"Incyte (United States)","ror":"https://ror.org/00cvzzg84","country_code":"US","type":"company","lineage":["https://openalex.org/I924451375"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert Assad","raw_affiliation_strings":["Incyte Corp. (United States)"],"affiliations":[{"raw_affiliation_string":"Incyte Corp. (United States)","institution_ids":["https://openalex.org/I924451375"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065429893","display_name":"Richard G. Abramson","orcid":"https://orcid.org/0000-0002-1200-0281"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard G. Abramson","raw_affiliation_strings":["Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075735203","display_name":"Bennett A. Landman","orcid":"https://orcid.org/0000-0001-5733-2127"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bennett A. Landman","raw_affiliation_strings":["Vanderbilt Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Vanderbilt Univ. (United States)","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5067191302"],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":null,"apc_paid":null,"fwci":1.6357,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.83805528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"10133","issue":null,"first_page":"101330A","last_page":"101330A"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11267","display_name":"Abdominal Trauma and Injuries","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9803000092506409,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7305809259414673},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5856592059135437},{"id":"https://openalex.org/keywords/atlas","display_name":"Atlas (anatomy)","score":0.5690433979034424},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5501983761787415},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5452724695205688},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5442765355110168},{"id":"https://openalex.org/keywords/contrast","display_name":"Contrast (vision)","score":0.48811468482017517},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2146373987197876},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.13980898261070251}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7305809259414673},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5856592059135437},{"id":"https://openalex.org/C2776673561","wikidata":"https://www.wikidata.org/wiki/Q655357","display_name":"Atlas (anatomy)","level":2,"score":0.5690433979034424},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5501983761787415},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5452724695205688},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5442765355110168},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.48811468482017517},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2146373987197876},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.13980898261070251}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2254147","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2254147","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmid:28649156","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28649156","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:europepmc.org:4327392","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5480961","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309599","display_name":"Vanderbilt Institute for Clinical and Translational Research","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W29951291","https://openalex.org/W251803591","https://openalex.org/W273955616","https://openalex.org/W1667869507","https://openalex.org/W1680164276","https://openalex.org/W1884695109","https://openalex.org/W1905695250","https://openalex.org/W1963789434","https://openalex.org/W1969229669","https://openalex.org/W1974842966","https://openalex.org/W1990109229","https://openalex.org/W1994687768","https://openalex.org/W2008176042","https://openalex.org/W2016974693","https://openalex.org/W2050542229","https://openalex.org/W2052788412","https://openalex.org/W2053588653","https://openalex.org/W2068688088","https://openalex.org/W2081439668","https://openalex.org/W2095700415","https://openalex.org/W2115560616","https://openalex.org/W2127567384","https://openalex.org/W2135513683","https://openalex.org/W2140067226","https://openalex.org/W2148157540","https://openalex.org/W2154105292","https://openalex.org/W2163595993","https://openalex.org/W2163605009","https://openalex.org/W2169846542","https://openalex.org/W2170187799","https://openalex.org/W2294233313","https://openalex.org/W2483265827","https://openalex.org/W4247431264","https://openalex.org/W6609445593","https://openalex.org/W6610017368","https://openalex.org/W6647905348","https://openalex.org/W6649221553"],"related_works":["https://openalex.org/W2314146950","https://openalex.org/W2011187995","https://openalex.org/W2373521488","https://openalex.org/W2324878645","https://openalex.org/W2803101231","https://openalex.org/W4284509","https://openalex.org/W4393084406","https://openalex.org/W606911313","https://openalex.org/W4229506690","https://openalex.org/W1522196789"],"abstract_inverted_index":{"Non-invasive":[0],"spleen":[1,25,77,108,236],"volume":[2,26],"estimation":[3,27,136],"is":[4,31,88,152,231],"essential":[5],"in":[6,20,159],"detecting":[7],"splenomegaly.":[8,80],"Magnetic":[9],"resonance":[10],"imaging":[11],"(MRI)":[12],"has":[13,49],"been":[14,50],"used":[15,186],"to":[16,52,57,70,154,162,187,233],"facilitate":[17],"splenomegaly":[18,97,241],"diagnosis":[19],"vivo.":[21],"However,":[22],"achieving":[23],"accurate":[24,235],"from":[28,170,238],"MR":[29],"images":[30],"challenging":[32],"given":[33],"the":[34,82,89,104,142,164,206,221,228,239],"great":[35],"inter-subject":[36],"variance":[37],"of":[38,44,84,107,126],"human":[39],"abdomens":[40],"and":[41,61,111,130,181,193],"wide":[42],"variety":[43],"clinical":[45,172],"images/modalities.":[46],"Multi-atlas":[47],"segmentation":[48,73,78,95,230,237],"shown":[51],"be":[53],"a":[54,124,156,160,171],"promising":[55],"approach":[56,121],"handle":[58],"heterogeneous":[59],"data":[60],"difficult":[62],"anatomical":[63],"scenarios.":[64],"In":[65],"this":[66,87],"paper,":[67],"we":[68],"propose":[69],"use":[71],"multi-atlas":[72,94,229],"frameworks":[74],"for":[75,79,96,133],"MRI":[76,176,242],"To":[81,102,139],"best":[83],"our":[85],"knowledge,":[86],"first":[90],"work":[91],"that":[92,227],"integrates":[93],"as":[98],"seen":[99],"on":[100],"MRI.":[101],"address":[103],"particular":[105],"concerns":[106],"MRI,":[109],"automated":[110,120,192],"novel":[112],"semi-automated":[113,144,194],"atlas":[114,149,166],"selection":[115,150],"approaches":[116],"are":[117],"introduced.":[118],"The":[119,201,224],"interactively":[122],"selects":[123],"subset":[125],"atlases":[127],"using":[128],"selective":[129],"iterative":[131,165],"method":[132],"performance":[134],"level":[135],"(SIMPLE)":[137],"approach.":[138],"further":[140],"control":[141],"outliers,":[143],"craniocaudal":[145],"length":[146],"based":[147],"SIMPLE":[148],"(L-SIMPLE)":[151],"proposed":[153],"introduce":[155],"spatial":[157],"prior":[158],"fashion":[161],"guide":[163],"selection.":[167],"A":[168],"dataset":[169],"trial":[173],"containing":[174],"55":[175],"volumes":[177],"(28":[178],"T1":[179],"weighted":[180],"27":[182],"T2":[183],"weighted)":[184],"was":[185],"evaluate":[188],"different":[189],"methods.":[190],"Both":[191],"methods":[195],"achieved":[196,215],"median":[197],"DSC":[198],">":[199],"0.9.":[200],"outliers":[202],"were":[203],"alleviated":[204],"by":[205],"L-SIMPLE":[207],"(\u22481":[208],"min":[209],"manual":[210,222],"efforts":[211],"per":[212],"scan),":[213],"which":[214],"0.9713":[216],"Pearson":[217],"correlation":[218],"compared":[219],"with":[220],"segmentation.":[223],"results":[225],"demonstrated":[226],"able":[232],"achieve":[234],"multi-contrast":[240],"scans.":[243]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}
