{"id":"https://openalex.org/W2594259100","doi":"https://doi.org/10.1117/12.2254034","title":"Improved brain tumor segmentation by utilizing tumor growth model in longitudinal brain MRI","display_name":"Improved brain tumor segmentation by utilizing tumor growth model in longitudinal brain MRI","publication_year":2017,"publication_date":"2017-03-03","ids":{"openalex":"https://openalex.org/W2594259100","doi":"https://doi.org/10.1117/12.2254034","mag":"2594259100","pmid":"https://pubmed.ncbi.nlm.nih.gov/28642629"},"language":"en","primary_location":{"id":"doi:10.1117/12.2254034","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2254034","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045820623","display_name":"Linmin Pei","orcid":"https://orcid.org/0000-0001-6135-9429"},"institutions":[{"id":"https://openalex.org/I4210138378","display_name":"Dominion (United States)","ror":"https://ror.org/038q98v71","country_code":"US","type":"company","lineage":["https://openalex.org/I4210138378"]},{"id":"https://openalex.org/I81365321","display_name":"Old Dominion University","ror":"https://ror.org/04zjtrb98","country_code":"US","type":"education","lineage":["https://openalex.org/I81365321"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linmin Pei","raw_affiliation_strings":["Old Dominion Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Old Dominion Univ. (United States)","institution_ids":["https://openalex.org/I4210138378","https://openalex.org/I81365321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109599518","display_name":"Syed M. S. Reza","orcid":null},"institutions":[{"id":"https://openalex.org/I4210138378","display_name":"Dominion (United States)","ror":"https://ror.org/038q98v71","country_code":"US","type":"company","lineage":["https://openalex.org/I4210138378"]},{"id":"https://openalex.org/I81365321","display_name":"Old Dominion University","ror":"https://ror.org/04zjtrb98","country_code":"US","type":"education","lineage":["https://openalex.org/I81365321"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Syed M. S. Reza","raw_affiliation_strings":["Old Dominion Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Old Dominion Univ. (United States)","institution_ids":["https://openalex.org/I4210138378","https://openalex.org/I81365321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100318457","display_name":"Wei Li","orcid":"https://orcid.org/0000-0003-4589-2711"},"institutions":[{"id":"https://openalex.org/I4210138378","display_name":"Dominion (United States)","ror":"https://ror.org/038q98v71","country_code":"US","type":"company","lineage":["https://openalex.org/I4210138378"]},{"id":"https://openalex.org/I81365321","display_name":"Old Dominion University","ror":"https://ror.org/04zjtrb98","country_code":"US","type":"education","lineage":["https://openalex.org/I81365321"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Li","raw_affiliation_strings":["Old Dominion Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Old Dominion Univ. (United States)","institution_ids":["https://openalex.org/I4210138378","https://openalex.org/I81365321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034999945","display_name":"Christos Davatzikos","orcid":"https://orcid.org/0000-0002-1025-8561"},"institutions":[{"id":"https://openalex.org/I36788626","display_name":"California University of Pennsylvania","ror":"https://ror.org/01spssf70","country_code":"US","type":"education","lineage":["https://openalex.org/I36788626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christos Davatzikos","raw_affiliation_strings":["Univ. of Pennsylvania (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania (United States)","institution_ids":["https://openalex.org/I36788626"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081863591","display_name":"Khan M. Iftekharuddin","orcid":"https://orcid.org/0000-0001-8316-4163"},"institutions":[{"id":"https://openalex.org/I4210138378","display_name":"Dominion (United States)","ror":"https://ror.org/038q98v71","country_code":"US","type":"company","lineage":["https://openalex.org/I4210138378"]},{"id":"https://openalex.org/I81365321","display_name":"Old Dominion University","ror":"https://ror.org/04zjtrb98","country_code":"US","type":"education","lineage":["https://openalex.org/I81365321"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Khan M. Iftekharuddin","raw_affiliation_strings":["Old Dominion Univ. (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Old Dominion Univ. (United States)","institution_ids":["https://openalex.org/I4210138378","https://openalex.org/I81365321"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2361,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.79848565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"10134","issue":null,"first_page":"101342L","last_page":"101342L"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6631139516830444},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.582000195980072},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5798152089118958},{"id":"https://openalex.org/keywords/brain-tumor","display_name":"Brain tumor","score":0.5312143564224243},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5215904116630554},{"id":"https://openalex.org/keywords/ground-truth","display_name":"Ground truth","score":0.47980430722236633},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.46647554636001587},{"id":"https://openalex.org/keywords/level-set-method","display_name":"Level set method","score":0.4569426476955414},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.12535765767097473},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.09594553709030151}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6631139516830444},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.582000195980072},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5798152089118958},{"id":"https://openalex.org/C2779130545","wikidata":"https://www.wikidata.org/wiki/Q233309","display_name":"Brain tumor","level":2,"score":0.5312143564224243},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5215904116630554},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.47980430722236633},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.46647554636001587},{"id":"https://openalex.org/C125269122","wikidata":"https://www.wikidata.org/wiki/Q1751397","display_name":"Level set method","level":4,"score":0.4569426476955414},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12535765767097473},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09594553709030151}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2254034","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2254034","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmid:28642629","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28642629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:europepmc.org:4714568","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5476314","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2679217100","display_name":null,"funder_award_id":"R01 EB020683","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G7122241443","display_name":null,"funder_award_id":"R15 CA115464","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W33787415","https://openalex.org/W118753260","https://openalex.org/W1635874285","https://openalex.org/W1641498739","https://openalex.org/W1983265956","https://openalex.org/W2028494674","https://openalex.org/W2037316890","https://openalex.org/W2037686028","https://openalex.org/W2042571173","https://openalex.org/W2044523788","https://openalex.org/W2068240772","https://openalex.org/W2102595307","https://openalex.org/W2136133666","https://openalex.org/W2221909736","https://openalex.org/W2286032140","https://openalex.org/W2413212170","https://openalex.org/W4240108859","https://openalex.org/W6601361697","https://openalex.org/W6604836615","https://openalex.org/W6636614683","https://openalex.org/W6660773531","https://openalex.org/W6688963265","https://openalex.org/W6715398145"],"related_works":["https://openalex.org/W1997160662","https://openalex.org/W1522196789","https://openalex.org/W2373659438","https://openalex.org/W2102683994","https://openalex.org/W2063813108","https://openalex.org/W4212875054","https://openalex.org/W2050783914","https://openalex.org/W2097403386","https://openalex.org/W2350912305","https://openalex.org/W2385310810"],"abstract_inverted_index":{"In":[0,26],"this":[1],"work,":[2],"we":[3,32],"propose":[4],"a":[5],"novel":[6,70],"method":[7,40,98],"to":[8,28],"improve":[9],"texture":[10,75],"based":[11],"tumor":[12,23,30,43,92,128],"segmentation":[13,129],"by":[14,37,117],"fusing":[15],"cell":[16,48],"density":[17,49,64],"patterns":[18,65],"that":[19,51],"are":[20],"generated":[21],"from":[22,106,110],"growth":[24,44],"modeling.":[25],"order":[27],"model":[29],"growth,":[31],"solve":[33],"the":[34,47,54,59,96,118],"reaction-diffusion":[35],"equation":[36],"using":[38,130],"Lattice-Boltzmann":[39],"(LBM).":[41],"Computational":[42],"modeling":[45],"obtains":[46],"distribution":[50],"potentially":[52],"indicates":[53],"predicted":[55],"tissue":[56],"locations":[57],"in":[58,87,136],"brain":[60,91],"over":[61],"time.":[62],"The":[63,121],"is":[66],"then":[67],"considered":[68],"as":[69,77],"features":[71,86],"along":[72],"with":[73,99],"other":[74],"(such":[76],"fractal,":[78],"and":[79,84],"multifractal":[80],"Brownian":[81],"motion":[82],"(mBm)),":[83],"intensity":[85],"MRI":[88,104],"for":[89,133],"improved":[90],"segmentation.":[93],"We":[94],"evaluate":[95],"proposed":[97],"about":[100],"one":[101],"hundred":[102],"longitudinal":[103,137],"scans":[105],"five":[107,134],"patients":[108,135],"obtained":[109],"public":[111],"BRATS":[112],"2015":[113],"data":[114],"set,":[115],"validated":[116],"ground":[119],"truth.":[120],"result":[122],"shows":[123],"significant":[124],"improvement":[125],"of":[126],"complete":[127],"ANOVA":[131],"analysis":[132],"MR":[138],"images.":[139]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-06-24T13:16:06.693445","created_date":"2025-10-10T00:00:00"}