{"id":"https://openalex.org/W2299801358","doi":"https://doi.org/10.1117/12.2217534","title":"Automatic pose correction for image-guided nonhuman primate brain surgery planning","display_name":"Automatic pose correction for image-guided nonhuman primate brain surgery planning","publication_year":2016,"publication_date":"2016-03-18","ids":{"openalex":"https://openalex.org/W2299801358","doi":"https://doi.org/10.1117/12.2217534","mag":"2299801358"},"language":"en","primary_location":{"id":"doi:10.1117/12.2217534","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2217534","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062044760","display_name":"Soheil Ghafurian","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]},{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Soheil Ghafurian","raw_affiliation_strings":["Merck Research Labs. (United States)","Rutgers Univ. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]},{"raw_affiliation_string":"Rutgers Univ. (United States)","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036328196","display_name":"Antong Chen","orcid":"https://orcid.org/0009-0008-3463-9650"},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Antong Chen","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034006801","display_name":"Catherine D. G. Hines","orcid":"https://orcid.org/0000-0001-9826-3164"},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine Hines","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050923318","display_name":"Belma Dogdas","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Belma Dogdas","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045079770","display_name":"Ashleigh Bone","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashleigh Bone","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023948235","display_name":"Kenneth Lodge","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Lodge","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028385864","display_name":"Stacey O\u2019Malley","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stacey O'Malley","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020143047","display_name":"Christopher T. Winkelmann","orcid":"https://orcid.org/0000-0001-8656-5069"},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher T. Winkelmann","raw_affiliation_strings":["Pfizer (United States)"],"affiliations":[{"raw_affiliation_string":"Pfizer (United States)","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103809543","display_name":"Ansuman Bagchi","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ansuman Bagchi","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003334349","display_name":"Laura S. Lubbers","orcid":"https://orcid.org/0000-0002-1645-9356"},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura S. Lubbers","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073747755","display_name":"Jason M. Uslaner","orcid":"https://orcid.org/0000-0002-8952-5940"},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason M. Uslaner","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103391067","display_name":"Colena Johnson","orcid":null},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colena Johnson","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087832273","display_name":"John J. Renger","orcid":"https://orcid.org/0000-0001-8418-8642"},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Renger","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089082078","display_name":"Hatim A. Zariwala","orcid":"https://orcid.org/0000-0002-2140-4149"},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hatim A. Zariwala","raw_affiliation_strings":["Merck Research Labs. (United States)"],"affiliations":[{"raw_affiliation_string":"Merck Research Labs. (United States)","institution_ids":["https://openalex.org/I1285764155"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5062044760"],"corresponding_institution_ids":["https://openalex.org/I102322142","https://openalex.org/I1285764155"],"apc_list":null,"apc_paid":null,"fwci":3.0921,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.91076217,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"9786","issue":null,"first_page":"97860O","last_page":"97860O"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10191","display_name":"Robotics and Sensor-Based Localization","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2202","display_name":"Aerospace Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10191","display_name":"Robotics and Sensor-Based Localization","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2202","display_name":"Aerospace Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11984","display_name":"Anatomy and Medical Technology","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9865999817848206,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7917749881744385},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7658910155296326},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.7407633662223816},{"id":"https://openalex.org/keywords/landmark","display_name":"Landmark","score":0.6100236177444458},{"id":"https://openalex.org/keywords/pose","display_name":"Pose","score":0.5864205956459045},{"id":"https://openalex.org/keywords/surgical-planning","display_name":"Surgical planning","score":0.5597739815711975},{"id":"https://openalex.org/keywords/image-registration","display_name":"Image registration","score":0.5138431191444397},{"id":"https://openalex.org/keywords/fiducial-marker","display_name":"Fiducial marker","score":0.5037221312522888},{"id":"https://openalex.org/keywords/rotation","display_name":"Rotation (mathematics)","score":0.4942765235900879},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.1992848813533783},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15191781520843506},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.1456926167011261}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7917749881744385},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7658910155296326},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.7407633662223816},{"id":"https://openalex.org/C2780297707","wikidata":"https://www.wikidata.org/wiki/Q4895393","display_name":"Landmark","level":2,"score":0.6100236177444458},{"id":"https://openalex.org/C52102323","wikidata":"https://www.wikidata.org/wiki/Q1671968","display_name":"Pose","level":2,"score":0.5864205956459045},{"id":"https://openalex.org/C2779370443","wikidata":"https://www.wikidata.org/wiki/Q1776627","display_name":"Surgical planning","level":2,"score":0.5597739815711975},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.5138431191444397},{"id":"https://openalex.org/C173974348","wikidata":"https://www.wikidata.org/wiki/Q1469893","display_name":"Fiducial marker","level":2,"score":0.5037221312522888},{"id":"https://openalex.org/C74050887","wikidata":"https://www.wikidata.org/wiki/Q848368","display_name":"Rotation (mathematics)","level":2,"score":0.4942765235900879},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.1992848813533783},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15191781520843506},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1456926167011261}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2217534","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2217534","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/11","display_name":"Sustainable cities and communities","score":0.6000000238418579}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1510320707","https://openalex.org/W1970928383","https://openalex.org/W2049505949","https://openalex.org/W2127890285","https://openalex.org/W2129357024","https://openalex.org/W6630713522","https://openalex.org/W6662848267"],"related_works":["https://openalex.org/W2056853153","https://openalex.org/W2057559274","https://openalex.org/W2005087563","https://openalex.org/W2378111931","https://openalex.org/W4243161226","https://openalex.org/W2950647290","https://openalex.org/W2620829895","https://openalex.org/W2356918560","https://openalex.org/W1968481813","https://openalex.org/W2392886708"],"abstract_inverted_index":{"Intracranial":[0],"delivery":[1],"of":[2,15,66,159,176,190],"recombinant":[3],"DNA":[4],"and":[5,89,96,127,136,148,166,179],"neurochemical":[6],"analysis":[7],"in":[8,23,46,53,72,118,145,192],"nonhuman":[9],"primate":[10],"(NHP)":[11],"requires":[12],"precise":[13],"targeting":[14,28],"various":[16],"brain":[17],"structures":[18],"via":[19],"imaging":[20],"derived":[21],"coordinates":[22],"stereotactic":[24,62,74,142],"surgeries.":[25],"To":[26],"attain":[27],"precision,":[29],"the":[30,48,58,61,67,70,73,86,114,119,124,141,146,150,160,170],"surgical":[31],"planning":[32],"needs":[33],"to":[34,57,69,110,113,139,163,168,196],"be":[35,77],"done":[36,78],"on":[37,85],"preoperative":[38],"three":[39],"dimensional":[40],"(3D)":[41],"CT":[42,90],"and/or":[43],"MR":[44,88],"images,":[45],"which":[47,121],"animals":[49],"head":[50],"is":[51,102],"fixed":[52],"a":[54,133,156,174,197],"pose":[55,59,71,199],"identical":[56],"during":[60],"surgery.":[63],"The":[64,152,183],"matching":[65],"image":[68,147],"frame":[75],"can":[76],"manually":[79],"by":[80],"detecting":[81],"key":[82],"anatomical":[83,171],"landmarks":[84,172],"3D":[87],"images":[91,120,162],"such":[92],"as":[93],"ear":[94,97],"canal":[95],"bar":[98],"zero":[99],"position.":[100],"This":[101],"not":[103],"only":[104],"time":[105],"intensive":[106],"but":[107],"also":[108],"prone":[109],"error":[111],"due":[112],"varying":[115],"initial":[116],"poses":[117],"affects":[122],"both":[123],"landmark":[125],"detection":[126],"rotation":[128],"estimation.":[129],"We":[130],"have":[131],"introduced":[132],"fast,":[134],"reproducible,":[135],"semi-automatic":[137],"method":[138,153],"detect":[140,169],"coordinate":[143],"system":[144],"correct":[149],"pose.":[151],"begins":[154],"with":[155],"rigid":[157],"registration":[158,181],"subject":[161],"an":[164],"atlas":[165],"proceeds":[167],"through":[173],"sequence":[175],"optimization,":[177],"deformable":[178],"multimodal":[180],"algorithms.":[182],"results":[184],"showed":[185],"similar":[186],"precision":[187],"(maximum":[188],"difference":[189],"1.71":[191],"average":[193],"in-plane":[194],"rotation)":[195],"manual":[198],"correction.":[200]},"counts_by_year":[{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}