{"id":"https://openalex.org/W2333819403","doi":"https://doi.org/10.1117/12.2217137","title":"Regional placental blood oxygen level dependent (BOLD) changes with gestational age in normally developing pregnancies using long duration R2* mapping in utero","display_name":"Regional placental blood oxygen level dependent (BOLD) changes with gestational age in normally developing pregnancies using long duration R2* mapping in utero","publication_year":2016,"publication_date":"2016-03-29","ids":{"openalex":"https://openalex.org/W2333819403","doi":"https://doi.org/10.1117/12.2217137","mag":"2333819403"},"language":"en","primary_location":{"id":"doi:10.1117/12.2217137","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2217137","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057636900","display_name":"Manjiri Dighe","orcid":"https://orcid.org/0000-0003-0047-5148"},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Manjiri Dighe","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112020189","display_name":"Yun Jung Kim","orcid":"https://orcid.org/0009-0003-4116-3383"},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yun Jung Kim","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081264796","display_name":"Sharmishtaa Seshamani","orcid":"https://orcid.org/0000-0001-7289-3184"},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharmishtaa Seshamani","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097040680","display_name":"Ania I. Blazejewska","orcid":null},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ania I. Blazejewska","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069284532","display_name":"Susan Mckown","orcid":null},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Mckown","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076361594","display_name":"Jason Caucutt","orcid":"https://orcid.org/0000-0001-6590-9248"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210106724","display_name":"Institute of Translational Health Sciences","ror":"https://ror.org/01cp21a44","country_code":"US","type":"other","lineage":["https://openalex.org/I4210106724"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Caucutt","raw_affiliation_strings":["ITHS, Univ. of Washington (United States)"],"affiliations":[{"raw_affiliation_string":"ITHS, Univ. of Washington (United States)","institution_ids":["https://openalex.org/I4210106724","https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020530606","display_name":"Christopher Gatenby","orcid":"https://orcid.org/0000-0002-5349-2446"},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Gatenby","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029437650","display_name":"Colin Studholme","orcid":"https://orcid.org/0000-0001-8683-6906"},"institutions":[{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colin Studholme","raw_affiliation_strings":["Univ. of Washington Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of Washington Medical Ctr. (United States)","institution_ids":["https://openalex.org/I2801852214"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5057636900"],"corresponding_institution_ids":["https://openalex.org/I2801852214"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0352209,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9788","issue":null,"first_page":"97881H","last_page":"97881H"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gestational-age","display_name":"Gestational age","score":0.817928671836853},{"id":"https://openalex.org/keywords/in-utero","display_name":"In utero","score":0.7382366061210632},{"id":"https://openalex.org/keywords/pregnancy","display_name":"Pregnancy","score":0.6732327938079834},{"id":"https://openalex.org/keywords/fetus","display_name":"Fetus","score":0.6690897345542908},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6488779783248901},{"id":"https://openalex.org/keywords/placenta","display_name":"Placenta","score":0.5797606110572815},{"id":"https://openalex.org/keywords/obstetrics","display_name":"Obstetrics","score":0.5691063404083252},{"id":"https://openalex.org/keywords/gestation","display_name":"Gestation","score":0.5205546617507935},{"id":"https://openalex.org/keywords/analysis-of-variance","display_name":"Analysis of variance","score":0.5135746002197266},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.21996816992759705},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0845237672328949}],"concepts":[{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.817928671836853},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.7382366061210632},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6732327938079834},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.6690897345542908},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6488779783248901},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.5797606110572815},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5691063404083252},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.5205546617507935},{"id":"https://openalex.org/C99476002","wikidata":"https://www.wikidata.org/wiki/Q42297","display_name":"Analysis of variance","level":2,"score":0.5135746002197266},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21996816992759705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0845237672328949},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2217137","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2217137","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8299999833106995,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W86858381","https://openalex.org/W1965749640","https://openalex.org/W1992360640","https://openalex.org/W1999913538","https://openalex.org/W2011330367","https://openalex.org/W4234863691","https://openalex.org/W4235897238","https://openalex.org/W6603531801","https://openalex.org/W6641445879"],"related_works":["https://openalex.org/W1985367435","https://openalex.org/W2998035693","https://openalex.org/W2943529843","https://openalex.org/W2371953778","https://openalex.org/W2128023456","https://openalex.org/W1600429541","https://openalex.org/W2041541548","https://openalex.org/W4213304622","https://openalex.org/W1531071039","https://openalex.org/W2954242942"],"abstract_inverted_index":{"The":[0],"aim":[1,23],"of":[2,10,18,24,40,44,62,135,153,174,177,204],"this":[3],"study":[4],"was":[5,71,115,194,196],"to":[6,73,101,126,129,150],"examine":[7],"the":[8,19,22,63,136,154,205,220,228],"use":[9],"R2*":[11,52,69,79,137,163,189,226],"mapping":[12],"in":[13,60,81,85,144,156,188,201,225],"maternal":[14],"and":[15,98,117,121,212],"fetal":[16,213],"sub-regions":[17,61],"placenta":[20],"with":[21,55,171,190,216,223],"providing":[25],"a":[26,38,75,131,148,157,169],"reference":[27],"for":[28,78,91],"blood":[29],"oxygenation":[30],"levels":[31],"during":[32,104,208],"normative":[33],"development.":[34],"There":[35],"have":[36,50],"been":[37],"number":[39],"MR":[41],"relaxation":[42],"studies":[43],"placental":[45,83],"tissues":[46],"in-utero,":[47],"but":[48],"none":[49],"reported":[51],"value":[53],"changes":[54,215],"age,":[56],"or":[57],"examined":[58],"differences":[59],"placenta.":[64],"Here":[65],"specialized":[66],"long-duration":[67],"Multi-frame":[68],"imaging":[70],"used":[72],"create":[74],"stable":[76],"estimate":[77,134],"values":[80],"different":[82],"regions":[84],"healthy":[86],"pregnant":[87],"volunteers":[88],"not":[89],"imaged":[90],"clinical":[92],"reasons.":[93],"27":[94],"subjects":[95],"were":[96,141,165],"recruited":[97],"scanned":[99],"up":[100],"3":[102,125],"times":[103,123],"their":[105,209],"pregnancy.":[106,210],"A":[107],"multi-slice":[108],"dual":[109],"echo":[110],"EPI":[111],"based":[112],"BOLD":[113],"acquisition":[114],"employed":[116],"repeated":[118,143],"between":[119],"90":[120],"150":[122],"over":[124,199,227],"5":[127],"minutes":[128],"provide":[130],"high":[132],"accuracy":[133],"signal":[138],"level.":[139],"Acquisitions":[140],"also":[142,197],"13":[145],"cases":[146],"within":[147,168],"visit":[149,170],"evaluate":[151],"reproducibility":[152],"method":[155],"given":[158],"subject.":[159],"Experimental":[160],"results":[161],"showed":[162],"measurements":[164],"highly":[166],"repeatable":[167],"standard":[172],"deviation":[173],"(0.76).":[175],"Plots":[176],"all":[178],"visits":[179,203],"against":[180],"gestational":[181,217,229],"age":[182,218],"indicated":[183],"clear":[184],"correlations":[185],"showing":[186],"decreases":[187],"age.":[191,230],"This":[192],"increase":[193,224],"consistent":[195,198],"time":[200],"multiple":[202],"same":[206,221],"volunteer":[207],"Maternal":[211],"regional":[214],"followed":[219],"trend":[222]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}