{"id":"https://openalex.org/W2331708176","doi":"https://doi.org/10.1117/12.2216402","title":"CT guided diffuse optical tomography for breast cancer imaging","display_name":"CT guided diffuse optical tomography for breast cancer imaging","publication_year":2016,"publication_date":"2016-03-29","ids":{"openalex":"https://openalex.org/W2331708176","doi":"https://doi.org/10.1117/12.2216402","mag":"2331708176"},"language":"en","primary_location":{"id":"doi:10.1117/12.2216402","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2216402","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017164341","display_name":"Reheman Baikejiang","orcid":"https://orcid.org/0000-0002-3994-731X"},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Reheman Baikejiang","raw_affiliation_strings":["Univ. of California, Merced (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of California, Merced (United States)","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741130","display_name":"Wei Zhang","orcid":"https://orcid.org/0000-0003-0140-8289"},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Zhang","raw_affiliation_strings":["Univ. of California, Merced (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of California, Merced (United States)","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085481857","display_name":"Dianwen Zhu","orcid":null},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dianwen Zhu","raw_affiliation_strings":["Univ. of California, Merced (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of California, Merced (United States)","institution_ids":["https://openalex.org/I156087764"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100624129","display_name":"Changqing Li","orcid":"https://orcid.org/0000-0003-4237-1494"},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Changqing Li","raw_affiliation_strings":["Univ. of California, Merced (United States)"],"affiliations":[{"raw_affiliation_string":"Univ. of California, Merced (United States)","institution_ids":["https://openalex.org/I156087764"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5017164341"],"corresponding_institution_ids":["https://openalex.org/I156087764"],"apc_list":null,"apc_paid":null,"fwci":0.8331,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.74366953,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"9788","issue":null,"first_page":"97882K","last_page":"97882K"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11588","display_name":"Atmospheric and Environmental Gas Dynamics","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffuse-optical-imaging","display_name":"Diffuse optical imaging","score":0.8414129018783569},{"id":"https://openalex.org/keywords/imaging-phantom","display_name":"Imaging phantom","score":0.6991238594055176},{"id":"https://openalex.org/keywords/breast-imaging","display_name":"Breast imaging","score":0.6849075555801392},{"id":"https://openalex.org/keywords/multispectral-image","display_name":"Multispectral image","score":0.6824482679367065},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.6307053565979004},{"id":"https://openalex.org/keywords/scanner","display_name":"Scanner","score":0.5416553020477295},{"id":"https://openalex.org/keywords/optical-tomography","display_name":"Optical tomography","score":0.5363166928291321},{"id":"https://openalex.org/keywords/image-resolution","display_name":"Image resolution","score":0.4646546244621277},{"id":"https://openalex.org/keywords/quantum-dot","display_name":"Quantum dot","score":0.4594913125038147},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.4465593099594116},{"id":"https://openalex.org/keywords/projection","display_name":"Projection (relational algebra)","score":0.4438697099685669},{"id":"https://openalex.org/keywords/tomography","display_name":"Tomography","score":0.4409255385398865},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.42891982197761536},{"id":"https://openalex.org/keywords/mammography","display_name":"Mammography","score":0.41344499588012695},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.4011183977127075},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3636932373046875},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.21821609139442444},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.2107475996017456},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.2098100483417511},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.15209099650382996},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.15043756365776062},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1380513608455658},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.101056307554245}],"concepts":[{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.8414129018783569},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.6991238594055176},{"id":"https://openalex.org/C2777432617","wikidata":"https://www.wikidata.org/wiki/Q22905905","display_name":"Breast imaging","level":5,"score":0.6849075555801392},{"id":"https://openalex.org/C173163844","wikidata":"https://www.wikidata.org/wiki/Q1761440","display_name":"Multispectral image","level":2,"score":0.6824482679367065},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.6307053565979004},{"id":"https://openalex.org/C2779751349","wikidata":"https://www.wikidata.org/wiki/Q1474480","display_name":"Scanner","level":2,"score":0.5416553020477295},{"id":"https://openalex.org/C2777413408","wikidata":"https://www.wikidata.org/wiki/Q1968843","display_name":"Optical tomography","level":3,"score":0.5363166928291321},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.4646546244621277},{"id":"https://openalex.org/C124657808","wikidata":"https://www.wikidata.org/wiki/Q1133068","display_name":"Quantum dot","level":2,"score":0.4594913125038147},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.4465593099594116},{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.4438697099685669},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.4409255385398865},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.42891982197761536},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.41344499588012695},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4011183977127075},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3636932373046875},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.21821609139442444},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.2107475996017456},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.2098100483417511},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.15209099650382996},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.15043756365776062},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1380513608455658},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.101056307554245},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2216402","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2216402","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5099999904632568}],"awards":[],"funders":[{"id":"https://openalex.org/F4320333031","display_name":"University of California Merced","ror":"https://ror.org/00d9ah105"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":77,"referenced_works":["https://openalex.org/W129639604","https://openalex.org/W1563853427","https://openalex.org/W1573293896","https://openalex.org/W1963659938","https://openalex.org/W1967594797","https://openalex.org/W1971666287","https://openalex.org/W1973083020","https://openalex.org/W1974663943","https://openalex.org/W1978243461","https://openalex.org/W1979313251","https://openalex.org/W1983592067","https://openalex.org/W1985808161","https://openalex.org/W1988518707","https://openalex.org/W1989489564","https://openalex.org/W1990501610","https://openalex.org/W1997006057","https://openalex.org/W1998901430","https://openalex.org/W2014899613","https://openalex.org/W2016052416","https://openalex.org/W2018175025","https://openalex.org/W2020942987","https://openalex.org/W2021358483","https://openalex.org/W2026592776","https://openalex.org/W2027595838","https://openalex.org/W2030766736","https://openalex.org/W2033106066","https://openalex.org/W2040568034","https://openalex.org/W2040626002","https://openalex.org/W2043489363","https://openalex.org/W2053480757","https://openalex.org/W2055286903","https://openalex.org/W2056493921","https://openalex.org/W2058474383","https://openalex.org/W2058652958","https://openalex.org/W2061135416","https://openalex.org/W2066351011","https://openalex.org/W2067164615","https://openalex.org/W2067858691","https://openalex.org/W2068313535","https://openalex.org/W2069009977","https://openalex.org/W2071293364","https://openalex.org/W2076414589","https://openalex.org/W2080600885","https://openalex.org/W2086819057","https://openalex.org/W2089499666","https://openalex.org/W2093893016","https://openalex.org/W2112787182","https://openalex.org/W2115485206","https://openalex.org/W2119165350","https://openalex.org/W2122937330","https://openalex.org/W2126807619","https://openalex.org/W2126905320","https://openalex.org/W2129685038","https://openalex.org/W2133863204","https://openalex.org/W2135927995","https://openalex.org/W2136810426","https://openalex.org/W2140403374","https://openalex.org/W2143163067","https://openalex.org/W2143786439","https://openalex.org/W2144255930","https://openalex.org/W2144636090","https://openalex.org/W2151744107","https://openalex.org/W2151904753","https://openalex.org/W2153367996","https://openalex.org/W2157619999","https://openalex.org/W2159695423","https://openalex.org/W2161005732","https://openalex.org/W2161169693","https://openalex.org/W2166045720","https://openalex.org/W4246383269","https://openalex.org/W6605218149","https://openalex.org/W6633541420","https://openalex.org/W6641097993","https://openalex.org/W6655043339","https://openalex.org/W6682342452","https://openalex.org/W6683670866","https://openalex.org/W6845573596"],"related_works":["https://openalex.org/W1997803613","https://openalex.org/W2073776015","https://openalex.org/W4253832138","https://openalex.org/W2037916999","https://openalex.org/W3010250986","https://openalex.org/W4385335355","https://openalex.org/W2748976997","https://openalex.org/W2090799487","https://openalex.org/W4242834832","https://openalex.org/W3026922260"],"abstract_inverted_index":{"Diffuse":[0],"optical":[1,45,178],"tomography":[2,67],"(DOT)":[3],"has":[4,30],"attracted":[5],"attentions":[6],"in":[7,17,47,123],"the":[8,58,111,135,157,177,186,199,202],"last":[9],"two":[10],"decades":[11],"due":[12,36],"to":[13,37,175],"its":[14,38,80],"intrinsic":[15],"sensitivity":[16],"imaging":[18,55,60,72,88,126,205],"chromophores":[19],"of":[20,92,97,133,137,201],"tissues":[21],"such":[22,129],"as":[23,130],"blood,":[24],"water,":[25],"and":[26,99,120,196],"lipid.":[27],"However,":[28],"DOT":[29,59,71,87,114,160,174,204],"not":[31],"been":[32,141],"clinically":[33],"accepted":[34],"yet":[35],"low":[39],"spatial":[40],"resolution":[41],"caused":[42],"by":[43,52],"strong":[44],"scattering":[46],"tissues.":[48],"Structural":[49],"guidance":[50,188],"provided":[51],"an":[53,100,147],"anatomical":[54],"modality":[56],"enhances":[57],"substantially.":[61],"Here,":[62],"we":[63,82,192],"propose":[64],"a":[65,85,93,208],"computed":[66],"(CT)":[68],"guided":[69,113],"multispectral":[70,203],"system":[73,89,206],"for":[74,156,173],"breast":[75,209],"cancer":[76],"detection.":[77],"To":[78],"validate":[79],"feasibility,":[81],"have":[83,109,140,163],"built":[84],"prototype":[86],"which":[90,124],"consists":[91],"laser":[94],"at":[95,168],"wavelengths":[96],"650":[98],"electron":[101],"multiplying":[102],"charge":[103],"coupled":[104],"device":[105],"(EMCCD)":[106],"camera.":[107],"We":[108,162],"validated":[110],"CT":[112,187,210],"reconstruction":[115],"algorithms":[116],"with":[117,150,180],"numerical":[118],"simulations":[119],"phantom":[121],"experiments,":[122],"different":[125],"setup":[127],"parameters,":[128],"projection":[131],"number":[132],"measurements,":[134],"width":[136],"measurement":[138],"patch,":[139],"investigated.":[142],"Our":[143],"results":[144],"indicate":[145],"that":[146,166],"EMCCD":[148],"camera":[149],"air":[151],"cooling":[152],"is":[153,189],"good":[154],"enough":[155],"transmission":[158],"mode":[159],"imaging.":[161],"also":[164],"found":[165],"measurements":[167],"six":[169],"projections":[170],"are":[171],"sufficient":[172],"reconstruct":[176],"targets":[179],"4":[181],"times":[182],"absorption":[183],"contrast":[184],"when":[185],"applied.":[190],"Finally,":[191],"report":[193],"our":[194],"effort":[195],"progress":[197],"on":[198],"integration":[200],"into":[207],"scanner.":[211]},"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}