{"id":"https://openalex.org/W2309014487","doi":"https://doi.org/10.1117/12.2214606","title":"Response monitoring using quantitative ultrasound methods and supervised dictionary learning in locally advanced breast cancer","display_name":"Response monitoring using quantitative ultrasound methods and supervised dictionary learning in locally advanced breast cancer","publication_year":2016,"publication_date":"2016-03-21","ids":{"openalex":"https://openalex.org/W2309014487","doi":"https://doi.org/10.1117/12.2214606","mag":"2309014487"},"language":"en","primary_location":{"id":"doi:10.1117/12.2214606","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2214606","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031884787","display_name":"Mehrdad J. Gangeh","orcid":"https://orcid.org/0000-0002-2907-3014"},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210167439","display_name":"Sunnybrook Hospital","ror":"https://ror.org/008kn1a71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004","https://openalex.org/I4210167439"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mehrdad J. Gangeh","raw_affiliation_strings":["Univ. of Toronto (Canada)","Sunnybrook Research Institute (Canada)","Sunnybrook Health Sciences Ctr. (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Toronto (Canada)","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Sunnybrook Research Institute (Canada)","institution_ids":["https://openalex.org/I4210167439","https://openalex.org/I4391768120"]},{"raw_affiliation_string":"Sunnybrook Health Sciences Ctr. (Canada)","institution_ids":["https://openalex.org/I1323843004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018764125","display_name":"Brandon Fung","orcid":null},"institutions":[{"id":"https://openalex.org/I4210167439","display_name":"Sunnybrook Hospital","ror":"https://ror.org/008kn1a71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004","https://openalex.org/I4210167439"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Brandon Fung","raw_affiliation_strings":["Sunnybrook Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sunnybrook Research Institute (Canada)","institution_ids":["https://openalex.org/I4210167439","https://openalex.org/I4391768120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044517600","display_name":"Hadi Tadayyon","orcid":null},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210167439","display_name":"Sunnybrook Hospital","ror":"https://ror.org/008kn1a71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004","https://openalex.org/I4210167439"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Hadi Tadayyon","raw_affiliation_strings":["Univ. of Toronto (Canada)","Sunnybrook Research Institute (Canada)","Sunnybrook Health Sciences Ctr. (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Toronto (Canada)","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Sunnybrook Research Institute (Canada)","institution_ids":["https://openalex.org/I4210167439","https://openalex.org/I4391768120"]},{"raw_affiliation_string":"Sunnybrook Health Sciences Ctr. (Canada)","institution_ids":["https://openalex.org/I1323843004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046342721","display_name":"William T. Tran","orcid":"https://orcid.org/0000-0002-0733-7234"},"institutions":[{"id":"https://openalex.org/I4210167439","display_name":"Sunnybrook Hospital","ror":"https://ror.org/008kn1a71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004","https://openalex.org/I4210167439"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"William T. Tran","raw_affiliation_strings":["Sunnybrook Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sunnybrook Research Institute (Canada)","institution_ids":["https://openalex.org/I4210167439","https://openalex.org/I4391768120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103136151","display_name":"Gregory J. Czarnota","orcid":"https://orcid.org/0000-0002-9973-4586"},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210167439","display_name":"Sunnybrook Hospital","ror":"https://ror.org/008kn1a71","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004","https://openalex.org/I4210167439"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Gregory J. Czarnota","raw_affiliation_strings":["Univ. of Toronto (Canada)","Sunnybrook Health Sciences Ctr. (Canada)","Sunnybrook Research Institute (Canada)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Toronto (Canada)","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Sunnybrook Health Sciences Ctr. (Canada)","institution_ids":["https://openalex.org/I1323843004"]},{"raw_affiliation_string":"Sunnybrook Research Institute (Canada)","institution_ids":["https://openalex.org/I4210167439","https://openalex.org/I4391768120"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.175,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.55361049,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9784","issue":null,"first_page":"978413","last_page":"978413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.553191065788269},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5498084425926208},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.467768132686615},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.39612454175949097},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3346656858921051},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.31033894419670105},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.27175402641296387},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.26246803998947144},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.16239038109779358}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.553191065788269},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5498084425926208},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.467768132686615},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.39612454175949097},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3346656858921051},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.31033894419670105},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.27175402641296387},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26246803998947144},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16239038109779358}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2214606","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2214606","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7599999904632568,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1480948843","https://openalex.org/W1579117680","https://openalex.org/W1892756525","https://openalex.org/W1970082212","https://openalex.org/W1975720861","https://openalex.org/W1989021837","https://openalex.org/W2010281224","https://openalex.org/W2013418965","https://openalex.org/W2019607817","https://openalex.org/W2040711614","https://openalex.org/W2043929537","https://openalex.org/W2050460554","https://openalex.org/W2060427373","https://openalex.org/W2084693381","https://openalex.org/W2101953144","https://openalex.org/W2109762309","https://openalex.org/W2112552549","https://openalex.org/W2117677224","https://openalex.org/W2125865219","https://openalex.org/W2130328119","https://openalex.org/W2145544165","https://openalex.org/W2159610922","https://openalex.org/W2166859022","https://openalex.org/W2293059961","https://openalex.org/W2328240776","https://openalex.org/W4229750588","https://openalex.org/W4255558933","https://openalex.org/W6628533670","https://openalex.org/W6634442978","https://openalex.org/W6637304570","https://openalex.org/W6652953849","https://openalex.org/W6660566126","https://openalex.org/W6676726796","https://openalex.org/W6678814708","https://openalex.org/W6681474176","https://openalex.org/W6688325169"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W3046775127","https://openalex.org/W3107602296","https://openalex.org/W4394896187","https://openalex.org/W3170094116","https://openalex.org/W4386462264","https://openalex.org/W4364306694","https://openalex.org/W4312192474","https://openalex.org/W4283697347"],"abstract_inverted_index":{"A":[0],"non-invasive":[1],"computer-aided-theragnosis":[2],"(CAT)":[3],"system":[4,25,73,229,239],"was":[5,26,104,130,166,217],"developed":[6,227],"for":[7,55,65,106],"the":[8,43,56,66,78,88,107,116,120,126,142,145,157,160,171,206,210,223,226],"early":[9],"assessment":[10],"of":[11,58,69,90,109,179,222,233,245],"responses":[12],"to":[13,41,60,75,132,156,168,193,236],"neoadjuvant":[14],"chemotherapy":[15],"in":[16,80,173,209],"patients":[17,59],"with":[18,152,240],"locally":[19],"advanced":[20],"breast":[21],"cancer.":[22],"The":[23,182,220],"CAT":[24,72,228,238],"based":[27,98],"on":[28,99],"quantitative":[29],"ultrasound":[30],"spectroscopy":[31],"methods":[32],"comprising":[33],"several":[34],"modules":[35],"including":[36],"feature":[37,110,127,184,202],"extraction,":[38,128],"a":[39,51,70,95,134,190,199,237],"metric":[40,165],"measure":[42,77,118,170,188],"dissimilarity":[44,117,161,187],"between":[45,119,144],"\u201cpre-\u201d":[46,121,149],"and":[47,50,86,115,122,150,186,204],"\u201cmid-treatment\u201d":[48,123,151],"scans,":[49],"supervised":[52,135],"learning":[53,137],"algorithm":[54],"classification":[57,224],"responders/non-responders.":[61],"One":[62],"major":[63],"requirement":[64],"successful":[67],"design":[68,108,133],"high-performance":[71],"is":[74],"accurately":[76],"changes":[79,172],"parametric":[81,113,174],"maps":[82,114,175],"before":[83],"treatment":[84,180],"onset":[85],"during":[87],"course":[89],"treatment.":[91],"To":[92],"this":[93],"end,":[94],"unified":[96],"framework":[97],"Hilbert-Schmidt":[100],"independence":[101],"criterion":[102],"(HSIC)":[103],"used":[105,131,189],"extraction":[111,185],"from":[112,148],"scans.":[124,158],"For":[125,159],"HSIC":[129],"dictionary":[136],"(SDL)":[138],"method":[139],"by":[140],"maximizing":[141],"dependency":[143],"scans":[146],"taken":[147],"\u201cdummy":[153],"labels\u201d":[154],"given":[155],"measure,":[162],"an":[163,177,231],"HSIC-based":[164,183],"employed":[167],"effectively":[169],"as":[176],"indication":[178],"effectiveness.":[181],"kernel":[191],"function":[192],"nonlinearly":[194],"transform":[195],"input":[196],"vectors":[197],"into":[198],"higher":[200],"dimensional":[201],"space":[203],"computed":[205],"population":[207],"means":[208],"new":[211],"space,":[212],"where":[213],"enhanced":[214],"group":[215],"separability":[216],"ideally":[218],"obtained.":[219],"results":[221],"using":[225,243],"indicated":[230],"improvement":[232],"performance":[234],"compared":[235],"basic":[241],"features":[242],"histogram":[244],"intensity.":[246]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}