{"id":"https://openalex.org/W2313777272","doi":"https://doi.org/10.1117/12.2208792","title":"Perfusion deficits and functional connectivity alterations in patients with post-traumatic stress disorder","display_name":"Perfusion deficits and functional connectivity alterations in patients with post-traumatic stress disorder","publication_year":2016,"publication_date":"2016-03-29","ids":{"openalex":"https://openalex.org/W2313777272","doi":"https://doi.org/10.1117/12.2208792","mag":"2313777272"},"language":"en","primary_location":{"id":"doi:10.1117/12.2208792","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2208792","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100654083","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0002-3205-3663"},"institutions":[{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Fourth Military Medical Univ. (China)"],"affiliations":[{"raw_affiliation_string":"Fourth Military Medical Univ. (China)","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019688153","display_name":"Baojuan Li","orcid":null},"institutions":[{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baojuan Li","raw_affiliation_strings":["Fourth Military Medical Univ. (China)"],"affiliations":[{"raw_affiliation_string":"Fourth Military Medical Univ. (China)","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100641174","display_name":"Xi Zhang","orcid":"https://orcid.org/0000-0001-7033-8478"},"institutions":[{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Zhang","raw_affiliation_strings":["Fourth Military Medical Univ. (China)"],"affiliations":[{"raw_affiliation_string":"Fourth Military Medical Univ. (China)","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045476053","display_name":"Linchuan Zhang","orcid":"https://orcid.org/0009-0008-3840-4648"},"institutions":[{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linchuan Zhang","raw_affiliation_strings":["Fourth Military Medical Univ. (China)"],"affiliations":[{"raw_affiliation_string":"Fourth Military Medical Univ. (China)","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100420704","display_name":"Liang Li","orcid":"https://orcid.org/0000-0003-0745-2571"},"institutions":[{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Li","raw_affiliation_strings":["Fourth Military Medical Univ. (China)"],"affiliations":[{"raw_affiliation_string":"Fourth Military Medical Univ. (China)","institution_ids":["https://openalex.org/I9916479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034743810","display_name":"Hongbing Lu","orcid":"https://orcid.org/0000-0003-4181-7239"},"institutions":[{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongbing Lu","raw_affiliation_strings":["Fourth Military Medical Univ. (China)"],"affiliations":[{"raw_affiliation_string":"Fourth Military Medical Univ. (China)","institution_ids":["https://openalex.org/I9916479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5100654083"],"corresponding_institution_ids":["https://openalex.org/I9916479"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01630275,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9788","issue":null,"first_page":"97881C","last_page":"97881C"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corpus-callosum","display_name":"Corpus callosum","score":0.7955172657966614},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"Cerebral blood flow","score":0.7274529337882996},{"id":"https://openalex.org/keywords/frontal-lobe","display_name":"Frontal lobe","score":0.5708206295967102},{"id":"https://openalex.org/keywords/perfusion","display_name":"Perfusion","score":0.49926280975341797},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.45676732063293457},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.4559900760650635},{"id":"https://openalex.org/keywords/superior-frontal-gyrus","display_name":"Superior frontal gyrus","score":0.4477732181549072},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.4282044470310211},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3953879177570343},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3624412417411804},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3049911856651306},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.2655993103981018},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.2379155457019806}],"concepts":[{"id":"https://openalex.org/C2778183499","wikidata":"https://www.wikidata.org/wiki/Q223851","display_name":"Corpus callosum","level":2,"score":0.7955172657966614},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.7274529337882996},{"id":"https://openalex.org/C2777127467","wikidata":"https://www.wikidata.org/wiki/Q749520","display_name":"Frontal lobe","level":2,"score":0.5708206295967102},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.49926280975341797},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45676732063293457},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4559900760650635},{"id":"https://openalex.org/C2775956885","wikidata":"https://www.wikidata.org/wiki/Q3064113","display_name":"Superior frontal gyrus","level":3,"score":0.4477732181549072},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.4282044470310211},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3953879177570343},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3624412417411804},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3049911856651306},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2655993103981018},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.2379155457019806}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2208792","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2208792","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6100000143051147,"id":"https://metadata.un.org/sdg/13","display_name":"Climate action"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W212537071","https://openalex.org/W1970822013","https://openalex.org/W1971493062","https://openalex.org/W1990326934","https://openalex.org/W2012822391","https://openalex.org/W2019782389","https://openalex.org/W2028273448","https://openalex.org/W2039964460","https://openalex.org/W2055255735","https://openalex.org/W2077950225","https://openalex.org/W2082872212","https://openalex.org/W2100872688","https://openalex.org/W2114046308","https://openalex.org/W2119682532","https://openalex.org/W2120120116","https://openalex.org/W2127962136","https://openalex.org/W2130135754","https://openalex.org/W2137560959","https://openalex.org/W4236909787","https://openalex.org/W4239336285","https://openalex.org/W4241294122","https://openalex.org/W4248222129"],"related_works":["https://openalex.org/W2770904273","https://openalex.org/W4385409756","https://openalex.org/W2133832918","https://openalex.org/W2992886487","https://openalex.org/W2113716335","https://openalex.org/W4385816453","https://openalex.org/W1901918953","https://openalex.org/W3163235980","https://openalex.org/W4248742874","https://openalex.org/W864962180"],"abstract_inverted_index":{"To":[0],"explore":[1],"the":[2,26,62,72,95,101,120,147,151,161,230],"alteration":[3],"in":[4,105,119,142,164,208],"cerebral":[5],"blood":[6],"flow":[7],"(CBF)":[8],"and":[9,21,84,128,178,193,198,205,227],"functional":[10,102,169],"connectivity":[11,103,170,173,199,207],"between":[12,76,174],"survivors":[13],"with":[14,160],"recent":[15,217],"onset":[16,218],"post-traumatic":[17],"stress":[18],"disorder":[19],"(PTSD)":[20],"without":[22],"PTSD,":[23],"survived":[24],"from":[25,94],"same":[27],"coal":[28],"mine":[29],"flood":[30],"disaster.":[31],"In":[32],"this":[33],"study,":[34],"a":[35,53,222],"processing":[36],"pipeline":[37],"using":[38,81,113],"arterial":[39],"spin":[40],"labeling":[41],"(ASL)":[42],"sequence":[43],"was":[44,57,108,140],"proposed.":[45],"Considering":[46],"low":[47],"spatial":[48],"resolution":[49],"of":[50,74,132,150,232],"ASL":[51],"sequence,":[52],"linear":[54],"regression":[55],"method":[56],"firstly":[58],"used":[59],"to":[60],"correct":[61],"partial":[63],"volume":[64],"(PV)":[65],"effect":[66],"for":[67,216],"better":[68],"CBF":[69,75,86,91,96,111,117,144,149,187],"estimation.":[70],"Then":[71],"alterations":[73],"two":[77],"groups":[78],"were":[79],"analyzed":[80],"both":[82],"uncorrected":[83,143],"PV-corrected":[85,114,186],"maps.":[87],"Based":[88],"on":[89],"altered":[90],"regions":[92,211],"detected":[93],"analysis":[97,112],"as":[98],"seed":[99],"regions,":[100],"abnormities":[104],"PTSD":[106,133,165,219],"patients":[107],"investigated.":[109],"The":[110,167,201],"maps":[115],"indicates":[116,171],"deficits":[118,204],"bilateral":[121],"frontal":[122,126,154,176],"lobe,":[123],"right":[124,129,137,152,179],"superior":[125,153],"gyrus":[127,155],"corpus":[130,138],"callosum":[131,139],"patients,":[134],"while":[135],"only":[136],"identified":[141],"analysis.":[145,200],"Furthermore,":[146],"regional":[148],"exhibits":[156,188],"significantly":[157],"negative":[158],"correlation":[159],"symptom":[162],"severity":[163,231],"patients.":[166],"resting-state":[168],"increased":[172],"left":[175],"lobe":[177],"parietal":[180],"lobe.":[181],"These":[182],"results":[183],"indicate":[184],"that":[185],"more":[189],"subtle":[190],"perfusion":[191,197,203],"changes":[192],"may":[194,212],"benefit":[195],"further":[196],"symptom-specific":[202],"aberrant":[206],"above":[209],"memory-related":[210],"be":[213],"putative":[214],"biomarkers":[215],"induced":[220],"by":[221],"single":[223],"prolonged":[224],"trauma":[225],"exposure":[226],"help":[228],"predict":[229],"PTSD.":[233]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}