{"id":"https://openalex.org/W1996873831","doi":"https://doi.org/10.1117/12.2082727","title":"Prognosis of intervertebral disc loss from diagnosis of degenerative disc disease","display_name":"Prognosis of intervertebral disc loss from diagnosis of degenerative disc disease","publication_year":2015,"publication_date":"2015-03-20","ids":{"openalex":"https://openalex.org/W1996873831","doi":"https://doi.org/10.1117/12.2082727","mag":"1996873831"},"language":"en","primary_location":{"id":"doi:10.1117/12.2082727","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2082727","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100444236","display_name":"Sen Li","orcid":"https://orcid.org/0000-0001-9906-0481"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"S. Li","raw_affiliation_strings":["Western Univ. (Canada)"],"affiliations":[{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026484113","display_name":"Amy Lin","orcid":"https://orcid.org/0000-0002-2505-7340"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Lin","raw_affiliation_strings":["Western Univ. (Canada)"],"affiliations":[{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046114429","display_name":"Keng Yeow Tay","orcid":"https://orcid.org/0000-0001-6101-3065"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Tay","raw_affiliation_strings":["Western Univ. (Canada)","Victoria Hosptial (Canada)"],"affiliations":[{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]},{"raw_affiliation_string":"Victoria Hosptial (Canada)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109175121","display_name":"Walter Romano","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Romano","raw_affiliation_strings":["Victoria Hospital (Canada)","Western Univ. (Canada)"],"affiliations":[{"raw_affiliation_string":"Victoria Hospital (Canada)","institution_ids":[]},{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113972055","display_name":"Said Osman","orcid":null},"institutions":[{"id":"https://openalex.org/I4210151658","display_name":"St Joseph's Health Care","ror":"https://ror.org/05rj7xr73","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Said Osman","raw_affiliation_strings":["St. Joseph's Health Care (Canada)","Western Univ. (Canada)"],"affiliations":[{"raw_affiliation_string":"St. Joseph's Health Care (Canada)","institution_ids":["https://openalex.org/I4210151658"]},{"raw_affiliation_string":"Western Univ. (Canada)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100444236"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.05100229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"9414","issue":null,"first_page":"94143E","last_page":"94143E"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.7361180186271667},{"id":"https://openalex.org/keywords/degenerative-disc-disease","display_name":"Degenerative disc disease","score":0.6591907143592834},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6569559574127197},{"id":"https://openalex.org/keywords/intervertebral-disc","display_name":"Intervertebral disc","score":0.5666521191596985},{"id":"https://openalex.org/keywords/degeneration","display_name":"Degeneration (medical)","score":0.4906274378299713},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4375765919685364},{"id":"https://openalex.org/keywords/limiting","display_name":"Limiting","score":0.43475258350372314},{"id":"https://openalex.org/keywords/degenerative-disease","display_name":"Degenerative disease","score":0.43236973881721497},{"id":"https://openalex.org/keywords/low-back-pain","display_name":"Low back pain","score":0.4214722812175751},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.367486834526062},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.25284355878829956},{"id":"https://openalex.org/keywords/lumbar","display_name":"Lumbar","score":0.06993666291236877}],"concepts":[{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7361180186271667},{"id":"https://openalex.org/C2778051963","wikidata":"https://www.wikidata.org/wiki/Q11773731","display_name":"Degenerative disc disease","level":3,"score":0.6591907143592834},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6569559574127197},{"id":"https://openalex.org/C2777755357","wikidata":"https://www.wikidata.org/wiki/Q502781","display_name":"Intervertebral disc","level":2,"score":0.5666521191596985},{"id":"https://openalex.org/C2779354088","wikidata":"https://www.wikidata.org/wiki/Q15467261","display_name":"Degeneration (medical)","level":2,"score":0.4906274378299713},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4375765919685364},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.43475258350372314},{"id":"https://openalex.org/C2777427615","wikidata":"https://www.wikidata.org/wiki/Q954257","display_name":"Degenerative disease","level":3,"score":0.43236973881721497},{"id":"https://openalex.org/C2780907711","wikidata":"https://www.wikidata.org/wiki/Q852163","display_name":"Low back pain","level":3,"score":0.4214722812175751},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.367486834526062},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.25284355878829956},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.06993666291236877},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2082727","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2082727","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4099999964237213,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W133787854","https://openalex.org/W212537071","https://openalex.org/W1966188170","https://openalex.org/W1972284365","https://openalex.org/W2006880043","https://openalex.org/W2020751391","https://openalex.org/W2025489519","https://openalex.org/W2034291770","https://openalex.org/W2035134692","https://openalex.org/W2046296065","https://openalex.org/W2053343876","https://openalex.org/W2060499860","https://openalex.org/W2082099159","https://openalex.org/W2103137694","https://openalex.org/W2108009806","https://openalex.org/W2111608210","https://openalex.org/W2114751029","https://openalex.org/W2122282746","https://openalex.org/W2128082448","https://openalex.org/W2153448337","https://openalex.org/W2170051899","https://openalex.org/W6605467982","https://openalex.org/W6656770936"],"related_works":["https://openalex.org/W2331522529","https://openalex.org/W2780946525","https://openalex.org/W2944451398","https://openalex.org/W2349938184","https://openalex.org/W2374825565","https://openalex.org/W2954869541","https://openalex.org/W2081377542","https://openalex.org/W2053025121","https://openalex.org/W41338987","https://openalex.org/W2997600695"],"abstract_inverted_index":{"Degenerative":[0],"Disc":[1,50],"Disease":[2],"(DDD)":[3],"is":[4,16,52,96],"one":[5,53],"of":[6,11,24,26,35,54,61,85,89,106,122,149],"the":[7,22,37,41,55,59,69,118,123,128,133,138],"most":[8],"common":[9],"causes":[10,48],"low":[12],"back":[13],"pain,":[14],"and":[15,87,131,147],"a":[17,152],"major":[18],"factor":[19],"in":[20,46,58,132],"limiting":[21],"quality":[23],"life":[25],"an":[27],"individual":[28,129],"usually":[29],"as":[30],"they":[31],"enter":[32],"older":[33],"stages":[34],"life,":[36],"disc":[38,91],"degeneration":[39],"reduces":[40],"shock":[42],"absorption":[43],"available":[44],"which":[45],"turn":[47],"pain.":[49],"loss":[51],"central":[56],"processes":[57],"pathogenesis":[60],"DDD.":[62],"In":[63],"this":[64],"study,":[65],"we":[66,135],"investigated":[67],"whether":[68],"image":[70,100],"texture":[71],"features":[72],"quantified":[73],"from":[74,114],"magnetic":[75],"resonance":[76],"imaging":[77],"(MRI)":[78],"could":[79],"be":[80],"appropriate":[81],"markers":[82,130],"for":[83,151],"diagnosis":[84,148],"DDD":[86,150],"prognosis":[88,105,146],"inter-vertebral":[90],"loss.":[92],"The":[93],"main":[94],"objective":[95],"to":[97,103,127,140,144],"use":[98],"simple":[99],"based":[101],"biomarkers":[102],"perform":[104],"spinal":[107],"diseases":[108],"using":[109],"non-invasive":[110],"procedures.":[111],"Our":[112],"results":[113],"65":[115],"subjects":[116],"proved":[117],"higher":[119],"success":[120],"rates":[121],"combination":[124],"marker":[125],"compared":[126],"future,":[134],"will":[136],"extend":[137],"study":[139],"other":[141],"spine":[142],"regions":[143],"allow":[145],"wider":[153],"region.":[154]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}