{"id":"https://openalex.org/W2079439360","doi":"https://doi.org/10.1117/12.2081547","title":"Dynamic myocardial perfusion in a porcine balloon-induced ischemia model using a prototype spectral detector CT","display_name":"Dynamic myocardial perfusion in a porcine balloon-induced ischemia model using a prototype spectral detector CT","publication_year":2015,"publication_date":"2015-03-19","ids":{"openalex":"https://openalex.org/W2079439360","doi":"https://doi.org/10.1117/12.2081547","mag":"2079439360","pmid":"https://pubmed.ncbi.nlm.nih.gov/31942087"},"language":"en","primary_location":{"id":"doi:10.1117/12.2081547","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2081547","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6961835","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034527469","display_name":"Rachid Fahmi","orcid":"https://orcid.org/0000-0001-8277-6125"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rachid Fahmi","raw_affiliation_strings":["Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","Case Western Reserve University, United#N#                     States"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","institution_ids":[]},{"raw_affiliation_string":"Case Western Reserve University, United#N#                     States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005898060","display_name":"Brendan Eck","orcid":"https://orcid.org/0000-0003-0971-4432"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brendan L. Eck","raw_affiliation_strings":["Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","Case Western Reserve University, United#N#                     States"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","institution_ids":[]},{"raw_affiliation_string":"Case Western Reserve University, United#N#                     States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016869850","display_name":"Anas Fares","orcid":null},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Case Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anas Fares","raw_affiliation_strings":["Cardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, 44106, USA","Univ. Hospitals Case Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Cardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"Univ. Hospitals Case Medical Ctr. (United States)","institution_ids":["https://openalex.org/I4210108791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056910295","display_name":"Jacob Levi","orcid":"https://orcid.org/0000-0001-9376-4170"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacob Levi","raw_affiliation_strings":["Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","Case Western Reserve University, United#N#                     States"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","institution_ids":[]},{"raw_affiliation_string":"Case Western Reserve University, United#N#                     States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101542596","display_name":"Hao Wu","orcid":"https://orcid.org/0000-0001-6993-8863"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hao Wu","raw_affiliation_strings":["Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","Case Western Reserve University, United#N#                     States"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","institution_ids":[]},{"raw_affiliation_string":"Case Western Reserve University, United#N#                     States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011834104","display_name":"Mani Vembar","orcid":null},"institutions":[{"id":"https://openalex.org/I4210131230","display_name":"Philips (United States)","ror":"https://ror.org/03kw6wr76","country_code":"US","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210131230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mani Vembar","raw_affiliation_strings":["Philips Healthcare, Cleveland, OH, 44143, USA","Philips Healthcare (United States)"],"affiliations":[{"raw_affiliation_string":"Philips Healthcare, Cleveland, OH, 44143, USA","institution_ids":["https://openalex.org/I4210131230"]},{"raw_affiliation_string":"Philips Healthcare (United States)","institution_ids":["https://openalex.org/I4210131230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053655315","display_name":"Amar Dhanantwari","orcid":"https://orcid.org/0000-0001-7482-6014"},"institutions":[{"id":"https://openalex.org/I4210131230","display_name":"Philips (United States)","ror":"https://ror.org/03kw6wr76","country_code":"US","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210131230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amar Dhanantwari","raw_affiliation_strings":["Philips Healthcare, Cleveland, OH, 44143, USA","Philips Healthcare (United States)"],"affiliations":[{"raw_affiliation_string":"Philips Healthcare, Cleveland, OH, 44143, USA","institution_ids":["https://openalex.org/I4210131230"]},{"raw_affiliation_string":"Philips Healthcare (United States)","institution_ids":["https://openalex.org/I4210131230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038142458","display_name":"Hiram G. Bezerra","orcid":"https://orcid.org/0000-0001-8973-2440"},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Case Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hiram G. Bezerra","raw_affiliation_strings":["Cardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, 44106, USA","Univ. Hospitals Case Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Cardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"Univ. Hospitals Case Medical Ctr. (United States)","institution_ids":["https://openalex.org/I4210108791"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059314323","display_name":"David L. Wilson","orcid":"https://orcid.org/0000-0001-9763-1463"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David L. Wilson","raw_affiliation_strings":["Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","Department of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA","Case Western Reserve University, United#N#                     States"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Case Western Reserve University, United#N#                     States","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5034527469"],"corresponding_institution_ids":["https://openalex.org/I58956616"],"apc_list":null,"apc_paid":null,"fwci":1.5808,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.82529383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"9417","issue":null,"first_page":"94170Y","last_page":"94170Y"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perfusion","display_name":"Perfusion","score":0.7391950488090515},{"id":"https://openalex.org/keywords/balloon","display_name":"Balloon","score":0.6122593879699707},{"id":"https://openalex.org/keywords/ischemia","display_name":"Ischemia","score":0.6081332564353943},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.5576844215393066},{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"Myocardial ischemia","score":0.5123270750045776},{"id":"https://openalex.org/keywords/perfusion-scanning","display_name":"Perfusion scanning","score":0.4195311367511749},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.39846837520599365},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3466406464576721},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3370756506919861},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32414036989212036},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.05920815467834473}],"concepts":[{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.7391950488090515},{"id":"https://openalex.org/C139059822","wikidata":"https://www.wikidata.org/wiki/Q183951","display_name":"Balloon","level":2,"score":0.6122593879699707},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.6081332564353943},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.5576844215393066},{"id":"https://openalex.org/C3017461755","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Myocardial ischemia","level":3,"score":0.5123270750045776},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.4195311367511749},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.39846837520599365},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3466406464576721},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3370756506919861},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32414036989212036},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.05920815467834473}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1117/12.2081547","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2081547","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmid:31942087","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31942087","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of SPIE--the International Society for Optical Engineering","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:6961835","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6961835","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6961835","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6961835","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc SPIE Int Soc Opt Eng","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.8700000047683716,"display_name":"Affordable and clean energy"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W51616355","https://openalex.org/W1484080302","https://openalex.org/W1934789023","https://openalex.org/W1970516435","https://openalex.org/W1972037630","https://openalex.org/W1973627526","https://openalex.org/W1973990800","https://openalex.org/W1993711531","https://openalex.org/W2000994625","https://openalex.org/W2049152314","https://openalex.org/W2063567835","https://openalex.org/W2067377776","https://openalex.org/W2078284051","https://openalex.org/W2082829237","https://openalex.org/W2083321631","https://openalex.org/W2092754534","https://openalex.org/W2124331477","https://openalex.org/W2124752113","https://openalex.org/W2142710957","https://openalex.org/W2149755434","https://openalex.org/W2150286687","https://openalex.org/W2162048153","https://openalex.org/W2162678893","https://openalex.org/W2168730277","https://openalex.org/W2716822650","https://openalex.org/W2831308397","https://openalex.org/W4211191293","https://openalex.org/W6643642937","https://openalex.org/W6643690121","https://openalex.org/W6663014783","https://openalex.org/W6671381359","https://openalex.org/W6683947701","https://openalex.org/W7075723658"],"related_works":["https://openalex.org/W2467919609","https://openalex.org/W3032083687","https://openalex.org/W2383101986","https://openalex.org/W2471267301","https://openalex.org/W2467341106","https://openalex.org/W2385340480","https://openalex.org/W2133730772","https://openalex.org/W2015301357","https://openalex.org/W2361304792","https://openalex.org/W2382734415"],"abstract_inverted_index":{"Myocardial":[0],"CT":[1,14,35],"perfusion":[2],"(CTP)":[3],"imaging":[4],"is":[5,84],"an":[6,264,306],"application":[7],"that":[8,194,273],"should":[9],"greatly":[10],"benefit":[11],"from":[12,149,296],"spectral":[13,33],"through":[15],"the":[16,114,169,187,201,231],"significant":[17],"reduction":[18,109,242],"of":[19,63,95,110,176,308],"beam":[20],"hardening":[21],"(BH)":[22],"artifacts":[23,120],"using":[24,66],"mono-energetic":[25],"(monoE)":[26,144],"image":[27],"reconstructions.":[28,161],"We":[29,128,151,256],"used":[30],"a":[31,56,67,85,173,300],"prototype":[32],"detector":[34,89],"(SDCT)":[36],"scanner":[37,83,116],"(Philips":[38],"Healthcare)":[39],"and":[40,47,97,107,136,141,153,181,191,270,281,305],"developed":[41],"advanced":[42],"processing":[43],"tools":[44],"(registration,":[45],"segmentation,":[46],"deconvolution-based":[48],"flow":[49,77,157,245],"estimation)":[50],"for":[51,146,315],"quantitative":[52],"myocardial":[53,155,174,232,254,321],"CTP":[54,130],"in":[55,172,186,203,243,303,319],"porcine":[57],"ischemia":[58],"model":[59],"with":[60,75,121,217,237],"different":[61,133,160,261,320],"degrees":[62],"coronary":[64],"occlusion":[65,71],"balloon":[68,163],"catheter.":[69],"The":[70,81],"severity":[72],"was":[73,246,312],"adjusted":[74],"fractional":[76],"reserve":[78],"(FFR)":[79],"measurements.":[80],"SDCT":[82,115],"single":[86],"source,":[87],"dual-layer":[88],"system,":[90],"which":[91],"allows":[92],"simultaneous":[93],"acquisitions":[94],"low":[96],"high":[98],"energy":[99],"projections,":[100],"hence":[101],"enabling":[102],"accurate":[103],"projection-based":[104,142],"material":[105],"decomposition":[106],"effective":[108],"BH-artifacts.":[111],"In":[112],"addition,":[113],"eliminates":[117],"partial":[118],"scan":[119],"fast":[122],"(0.27s),":[123],"full":[124],"gantry":[125],"rotation":[126],"acquisitions.":[127],"acquired":[129],"data":[131,239],"under":[132,223,263],"hemodynamic":[134],"conditions":[135],"reconstructed":[137],"conventional":[138,218,316],"120kVp":[139,219,238,317],"images":[140,145,196,318],"monoenergetic":[143],"energies":[147,294],"ranging":[148],"55keV-to-120keV.":[150],"computed":[152],"compared":[154,168,213,251,257],"blood":[156,244],"(MBF)":[158],"between":[159,278],"With":[162],"completely":[164],"deflated":[165],"(FFR=1),":[166],"we":[167,192,271,298],"mean":[170],"attenuation":[171],"region":[175],"interest":[177],"before":[178],"iodine":[179,184],"arrival":[180],"at":[182,197,234,260,291],"peak":[183],"enhancement":[185],"left":[188],"ventricle":[189],"(LV),":[190],"found":[193,272],"monoE":[195],"70keV":[198],"effectively":[199],"minimized":[200],"difference":[202],"attenuation,":[204],"due":[205],"to":[206,208,214,252],"BH,":[207],"less":[209],"than":[210],"1":[211],"HU":[212,216],"14":[215],"images.":[220],"Flow":[221,310],"maps":[222,259],"baseline":[224],"condition":[225,266],"(FFR=1)":[226],"were":[227],"more":[228],"uniform":[229],"throughout":[230],"wall":[233],"70keV,":[235,297],"whereas":[236],"about":[240],"12%":[241],"noticed":[247,299,314],"on":[248],"BH-hypoattenuated":[249],"areas":[250],"other":[253],"regions.":[255,322],"MBF":[258],"keVs":[262],"ischemic":[265,280],"(FFR":[267],"<i><</i>":[268],"0.7),":[269],"flow-contrast-to-noise-ratio":[274],"(<i>CNR</i>":[275],"<sub><i>f</i></sub>":[276],")":[277],"LAD":[279],"remote":[282],"healthy":[283],"territories":[284],"attains":[285],"its":[286],"maximum":[287],"(2.87":[288],"\u00b1":[289],"0.7)":[290],"70keV.":[292],"As":[293],"diverge":[295],"steady":[301],"decrease":[302],"<i>CNRf</i>":[304],"overestimation":[307,311],"mean-MBF.":[309],"also":[313]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}