{"id":"https://openalex.org/W2053854656","doi":"https://doi.org/10.1117/12.2081485","title":"Combined use of high-definition and volumetric optical coherence tomography for the segmentation of neural canal opening in cases of optic nerve edema","display_name":"Combined use of high-definition and volumetric optical coherence tomography for the segmentation of neural canal opening in cases of optic nerve edema","publication_year":2015,"publication_date":"2015-03-20","ids":{"openalex":"https://openalex.org/W2053854656","doi":"https://doi.org/10.1117/12.2081485","mag":"2053854656"},"language":"en","primary_location":{"id":"doi:10.1117/12.2081485","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2081485","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045926452","display_name":"Jui-Kai Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jui-Kai Wang","raw_affiliation_strings":["The Univ. of Iowa  (United States)"],"affiliations":[{"raw_affiliation_string":"The Univ. of Iowa  (United States)","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026435996","display_name":"Randy H. Kardon","orcid":"https://orcid.org/0000-0002-3173-7123"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]},{"id":"https://openalex.org/I4210132647","display_name":"Iowa City VA Health Care System","ror":"https://ror.org/04hgm3062","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210132647","https://openalex.org/I4210159720"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randy H. Kardon","raw_affiliation_strings":["The Univ. of Iowa  (United States)","Iowa City VA Health Care System (United States)"],"affiliations":[{"raw_affiliation_string":"The Univ. of Iowa  (United States)","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Iowa City VA Health Care System (United States)","institution_ids":["https://openalex.org/I4210132647"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032968409","display_name":"Mona K. Garvin","orcid":"https://orcid.org/0000-0003-3299-3150"},"institutions":[{"id":"https://openalex.org/I4210132647","display_name":"Iowa City VA Health Care System","ror":"https://ror.org/04hgm3062","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210132647","https://openalex.org/I4210159720"]},{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mona K. Garvin","raw_affiliation_strings":["Iowa City VA Health Care System (United States)","The Univ. of Iowa (United States)"],"affiliations":[{"raw_affiliation_string":"Iowa City VA Health Care System (United States)","institution_ids":["https://openalex.org/I4210132647"]},{"raw_affiliation_string":"The Univ. of Iowa (United States)","institution_ids":["https://openalex.org/I126307644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045926452"],"corresponding_institution_ids":["https://openalex.org/I126307644"],"apc_list":null,"apc_paid":null,"fwci":1.2873,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.80097789,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"9413","issue":null,"first_page":"94133V","last_page":"94133V"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9761999845504761,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"Optical coherence tomography","score":0.7673318386077881},{"id":"https://openalex.org/keywords/raster-graphics","display_name":"Raster graphics","score":0.7406740188598633},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.69682776927948},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6577728986740112},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6381343603134155},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5613529086112976},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.5026462078094482},{"id":"https://openalex.org/keywords/optic-nerve","display_name":"Optic nerve","score":0.4806429445743561},{"id":"https://openalex.org/keywords/visibility","display_name":"Visibility","score":0.4734213948249817},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.41233834624290466},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.2081581950187683},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20119944214820862},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.16545847058296204},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1300162374973297}],"concepts":[{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.7673318386077881},{"id":"https://openalex.org/C181844469","wikidata":"https://www.wikidata.org/wiki/Q182270","display_name":"Raster graphics","level":2,"score":0.7406740188598633},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.69682776927948},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6577728986740112},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6381343603134155},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5613529086112976},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.5026462078094482},{"id":"https://openalex.org/C2780837183","wikidata":"https://www.wikidata.org/wiki/Q186029","display_name":"Optic nerve","level":2,"score":0.4806429445743561},{"id":"https://openalex.org/C123403432","wikidata":"https://www.wikidata.org/wiki/Q654068","display_name":"Visibility","level":2,"score":0.4734213948249817},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.41233834624290466},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.2081581950187683},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20119944214820862},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.16545847058296204},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1300162374973297}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2081485","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2081485","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1973369190","https://openalex.org/W1981279064","https://openalex.org/W1993227908","https://openalex.org/W1994799882","https://openalex.org/W2083181574","https://openalex.org/W2127318120","https://openalex.org/W2128409098","https://openalex.org/W2132768257","https://openalex.org/W2149954051"],"related_works":["https://openalex.org/W2392812199","https://openalex.org/W4200176076","https://openalex.org/W598185802","https://openalex.org/W2355516524","https://openalex.org/W2361471170","https://openalex.org/W2025616642","https://openalex.org/W1954972543","https://openalex.org/W2954738200","https://openalex.org/W4226107239","https://openalex.org/W4280562100"],"abstract_inverted_index":{"In":[0,63,95],"cases":[1,78],"of":[2,7,13,37,42,74,79,159],"optic-nerve-head":[3],"edema,":[4],"the":[5,8,11,14,35,38,43,72,75,105,114,122,136,153,164,169,179,183,192,202],"presence":[6],"swelling":[9],"reduces":[10],"visibility":[12,41],"underlying":[15],"neural":[16],"canal":[17],"opening":[18],"(NCO)":[19],"within":[20],"spectral-domain":[21],"optical":[22],"coherence":[23],"tomography":[24],"(SD-OCT)":[25],"volumes.":[26],"Consequently,":[27],"traditional":[28,208],"SD-OCT-based":[29],"NCO":[30,44,76,127,181,189,204],"segmentation":[31,73],"methods":[32],"often":[33],"overestimate":[34],"size":[36],"NCO.":[39],"The":[40,187],"can":[45],"be":[46],"improved":[47],"using":[48,191,206],"high-definition":[49,90,101,116,139],"2D":[50],"raster":[51,91],"scans,":[52,171],"but":[53],"such":[54],"scans":[55],"do":[56],"not":[57],"provide":[58],"3D":[59,165],"contextual":[60],"image":[61,85,93,166],"information.":[62],"this":[64,133],"work,":[65],"we":[66],"present":[67],"a":[68,157,172,207],"semi-automated":[69],"approach":[70,174,194,209],"for":[71,97,144],"in":[77,132,135,214],"optic":[80],"disc":[81],"edema":[82],"by":[83],"combining":[84],"information":[86,167],"from":[87,168],"volumetric":[88,170],"and":[89,104,112,148,163],"SD-OCT":[92],"sequences.":[94],"particular,":[96],"each":[98,145],"subject,":[99],"five":[100,115],"OCT":[102,106,123,140,154,184],"B-scans":[103,117,141],"volume":[107],"are":[108,118,129,149],"first":[109],"separately":[110],"segmented,":[111],"then":[113],"automatically":[119,150],"registered":[120],"to":[121,177,198],"volume.":[124,155],"Next,":[125],"six":[126],"points":[128,143,162,190,200,205],"placed":[130],"(manually,":[131],"work)":[134],"central":[137,146],"three":[138],"(two":[142],"B-scans)":[147],"transferred":[151],"into":[152],"Utilizing":[156],"combination":[158],"these":[160],"mapped":[161],"graph-based":[173],"is":[175],"used":[176],"identify":[178],"complete":[180],"on":[182],"en-face":[185],"image.":[186],"segmented":[188,203],"new":[193],"were":[195],"significantly":[196],"closer":[197],"expert-marked":[199],"than":[201],"(root":[210],"mean":[211],"square":[212],"differences":[213],"pixels:":[215],"5.34":[216],"vs.":[217],"21.71,":[218],"<i>p":[219],"</i>&lt;":[220],"0.001).":[221]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}