{"id":"https://openalex.org/W1981799498","doi":"https://doi.org/10.1117/12.2043712","title":"Locally constrained active contour: a region-based level set for ovarian cancer metastasis segmentation","display_name":"Locally constrained active contour: a region-based level set for ovarian cancer metastasis segmentation","publication_year":2014,"publication_date":"2014-03-21","ids":{"openalex":"https://openalex.org/W1981799498","doi":"https://doi.org/10.1117/12.2043712","mag":"1981799498"},"language":"en","primary_location":{"id":"doi:10.1117/12.2043712","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2043712","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101543443","display_name":"Jianfei Liu","orcid":"https://orcid.org/0000-0001-9885-1695"},"institutions":[{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jianfei Liu","raw_affiliation_strings":["National Institutes of Health Clinical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"National Institutes of Health Clinical Ctr. (United States)","institution_ids":["https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100695406","display_name":"Jianhua Yao","orcid":"https://orcid.org/0000-0001-9157-9596"},"institutions":[{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianhua Yao","raw_affiliation_strings":["National Institutes of Health Clinical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"National Institutes of Health Clinical Ctr. (United States)","institution_ids":["https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100627213","display_name":"Shijun Wang","orcid":"https://orcid.org/0000-0002-2873-8432"},"institutions":[{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shijun Wang","raw_affiliation_strings":["National Institutes of Health Clinical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"National Institutes of Health Clinical Ctr. (United States)","institution_ids":["https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085732379","display_name":"Marius George Linguraru","orcid":"https://orcid.org/0000-0001-6175-8665"},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marius George Linguraru","raw_affiliation_strings":["Children's National Medical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"Children's National Medical Ctr. (United States)","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016047550","display_name":"Ronald M. Summers","orcid":"https://orcid.org/0000-0001-8081-7376"},"institutions":[{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald M. Summers","raw_affiliation_strings":["National Institutes of Health Clinical Ctr. (United States)"],"affiliations":[{"raw_affiliation_string":"National Institutes of Health Clinical Ctr. (United States)","institution_ids":["https://openalex.org/I4210155647"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5101543443"],"corresponding_institution_ids":["https://openalex.org/I4210155647"],"apc_list":null,"apc_paid":null,"fwci":0.2439,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.55728638,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9034","issue":null,"first_page":"903404","last_page":"903404"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/active-contour-model","display_name":"Active contour model","score":0.8162235021591187},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"Ovarian cancer","score":0.6793978810310364},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6106788516044617},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5807275772094727},{"id":"https://openalex.org/keywords/metastasis","display_name":"Metastasis","score":0.5588701963424683},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.4727802276611328},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.44223445653915405},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.41239288449287415},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.40357741713523865},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3713643550872803},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3317807912826538},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2771102786064148},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.21956539154052734}],"concepts":[{"id":"https://openalex.org/C112353826","wikidata":"https://www.wikidata.org/wiki/Q127313","display_name":"Active contour model","level":4,"score":0.8162235021591187},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.6793978810310364},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6106788516044617},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5807275772094727},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5588701963424683},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4727802276611328},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.44223445653915405},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.41239288449287415},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.40357741713523865},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3713643550872803},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3317807912826538},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2771102786064148},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21956539154052734},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2043712","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2043712","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7799999713897705,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W189410843","https://openalex.org/W1238092070","https://openalex.org/W1543363024","https://openalex.org/W1604679511","https://openalex.org/W1896442311","https://openalex.org/W1918539434","https://openalex.org/W2023548024","https://openalex.org/W2044267436","https://openalex.org/W2050542229","https://openalex.org/W2115664739","https://openalex.org/W2116040950","https://openalex.org/W2117802366","https://openalex.org/W2125385057","https://openalex.org/W2130706954","https://openalex.org/W2132363464","https://openalex.org/W2164822588","https://openalex.org/W2171890357","https://openalex.org/W2432517183","https://openalex.org/W3004157836","https://openalex.org/W3211330693","https://openalex.org/W6607738584","https://openalex.org/W6632582182","https://openalex.org/W6701575323"],"related_works":["https://openalex.org/W2387003628","https://openalex.org/W123102278","https://openalex.org/W2081609930","https://openalex.org/W4239523971","https://openalex.org/W1522196789","https://openalex.org/W4210537690","https://openalex.org/W2885157826","https://openalex.org/W2159463658","https://openalex.org/W4388208420","https://openalex.org/W2051067977"],"abstract_inverted_index":{"Accurate":[0],"segmentation":[1],"of":[2],"ovarian":[3,29,112],"cancer":[4,30,113],"metastases":[5,114],"is":[6,34,49,78],"clinically":[7],"useful":[8],"to":[9,27,99],"evaluate":[10],"tumor":[11],"growth":[12],"and":[13,92,130,150],"determine":[14],"follow-up":[15],"treatment.":[16],"We":[17],"present":[18],"a":[19,37,64,70],"region-based":[20,39],"level":[21,40,60,86,97,167],"set":[22,61,87,98,168],"algorithm":[23,129,164],"with":[24,115],"localization":[25,72,90],"constraints":[26],"segment":[28],"metastases.":[31],"Our":[32,106],"approach":[33,107],"established":[35],"on":[36,110,118],"representative":[38],"set,":[41],"Chan-Vese":[42],"model,":[43],"in":[44],"which":[45],"an":[46],"active":[47,132],"contour":[48,133],"driven":[50],"by":[51,68],"region":[52],"competition.":[53],"To":[54],"reduce":[55],"over-segmentation,":[56],"we":[57],"constrain":[58],"the":[59,85,96,102,136,143,151],"propagation":[62],"within":[63,84],"narrow":[65],"image":[66,82],"band":[67],"embedding":[69],"dynamic":[71],"function.":[73],"The":[74,89,125],"metastasis":[75,104],"intensity":[76,93],"prior":[77,94],"also":[79],"estimated":[80],"from":[81,122],"regions":[83],"initialization.":[88],"function":[91],"force":[95],"stop":[100],"at":[101],"desired":[103],"boundaries.":[105],"was":[108,139,146,155],"validated":[109],"19":[111],"radiologist-labeled":[116],"ground-truth":[117],"contrast-enhanced":[119],"CT":[120],"scans":[121],"15":[123],"patients.":[124],"comparison":[126],"between":[127],"our":[128,163],"geodesic":[131],"indicated":[134],"that":[135,162],"volume":[137],"overlap":[138],"75±10%":[140],"vs.":[141,148,157],"56±6%,":[142],"Dice":[144],"coefficient":[145],"83±8%":[147],"63±8%,":[149],"average":[152],"surface":[153],"distance":[154],"2.2±0.6mm":[156],"4.4±0.9mm.":[158],"Experimental":[159],"results":[160],"demonstrated":[161],"outperformed":[165],"traditional":[166],"algorithms.":[169]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}