{"id":"https://openalex.org/W2013747282","doi":"https://doi.org/10.1117/12.2043009","title":"Sparse and shrunken estimates of MRI networks in the brain and their influence on network properties","display_name":"Sparse and shrunken estimates of MRI networks in the brain and their influence on network properties","publication_year":2014,"publication_date":"2014-03-21","ids":{"openalex":"https://openalex.org/W2013747282","doi":"https://doi.org/10.1117/12.2043009","mag":"2013747282"},"language":"en","primary_location":{"id":"doi:10.1117/12.2043009","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2043009","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024646528","display_name":"Rafael Romero-Garc\u00eda","orcid":"https://orcid.org/0000-0002-5199-4573"},"institutions":[{"id":"https://openalex.org/I95013407","display_name":"Universidad Pablo de Olavide","ror":"https://ror.org/02z749649","country_code":"ES","type":"education","lineage":["https://openalex.org/I95013407"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Rafael Romero-Garcia","raw_affiliation_strings":["Univ. Pablo de Olavide (Spain)","University Pablo de Olavide, Spain,#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Pablo de Olavide (Spain)","institution_ids":["https://openalex.org/I95013407"]},{"raw_affiliation_string":"University Pablo de Olavide, Spain,#TAB#","institution_ids":["https://openalex.org/I95013407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011062522","display_name":"Line Katrine Harder Clemmensen","orcid":"https://orcid.org/0000-0001-5527-5798"},"institutions":[{"id":"https://openalex.org/I96673099","display_name":"Technical University of Denmark","ror":"https://ror.org/04qtj9h94","country_code":"DK","type":"education","lineage":["https://openalex.org/I96673099"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Line H. Clemmensen","raw_affiliation_strings":["Technical Univ. of Denmark (Denmark)","Technical University of Denmark,Denmark)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical Univ. of Denmark (Denmark)","institution_ids":["https://openalex.org/I96673099"]},{"raw_affiliation_string":"Technical University of Denmark,Denmark)","institution_ids":["https://openalex.org/I96673099"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08498645,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9034","issue":null,"first_page":"903428","last_page":"903428"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5663565397262573},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.34873998165130615}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5663565397262573},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34873998165130615}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1117/12.2043009","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2043009","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.atira.dk:publications/7609ab42-6d59-4647-ba1a-09d69cc21755","is_oa":false,"landing_page_url":"https://orbit.dtu.dk/en/publications/7609ab42-6d59-4647-ba1a-09d69cc21755","pdf_url":null,"source":{"id":"https://openalex.org/S4306400705","display_name":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I96673099","host_organization_name":"Technical University of Denmark","host_organization_lineage":["https://openalex.org/I96673099"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Romero-Garcia , R & Clemmensen , L K H 2014 , ' Sparse and shrunken estimates of MRI networks in the brain and their influence on network properties ' , Progress in Biomedical Optics and Imaging - Proceedings of SPIE , vol. 9034 , 903428 . https://doi.org/10.1117/12.2043009","raw_type":"contributionToPeriodical"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W212537071","https://openalex.org/W1990512452","https://openalex.org/W1994239403","https://openalex.org/W2000574253","https://openalex.org/W2001334414","https://openalex.org/W2007829231","https://openalex.org/W2009650955","https://openalex.org/W2040803044","https://openalex.org/W2047028564","https://openalex.org/W2050852481","https://openalex.org/W2060464767","https://openalex.org/W2086568497","https://openalex.org/W2088471074","https://openalex.org/W2112090702","https://openalex.org/W2116474941","https://openalex.org/W2122825543","https://openalex.org/W2127606248","https://openalex.org/W2133015986","https://openalex.org/W2135046866","https://openalex.org/W2150534249","https://openalex.org/W2151346267","https://openalex.org/W2167822639","https://openalex.org/W4234173777","https://openalex.org/W4250276848","https://openalex.org/W6680156768","https://openalex.org/W6682374009"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Estimation":[0],"of":[1,21,61,69,75,77,100,145,150,200],"morphometric":[2],"relationships":[3],"between":[4],"cortical":[5,146],"regions":[6,22],"is":[7],"a":[8,28,58,66,93,101,135,141],"widely":[9],"used":[10],"approach":[11],"to":[12,34,72,126],"identify":[13],"and":[14,109,163,170,175],"characterize":[15],"structural":[16],"connectivity.":[17],"The":[18,193],"elevated":[19],"number":[20,60],"that":[23,134],"can":[24,40,139],"be":[25,41],"considered":[26],"in":[27,113,184,197],"whole-brain":[29],"correlation":[30,152,186],"analysis":[31],"might":[32],"lead":[33],"overfitted":[35],"models.":[36],"However,":[37,65],"the":[38,82,85,98,151,180,201,204],"overfitting":[39],"avoided":[42],"by":[43],"using":[44],"regularization":[45,149,155],"methods.":[46],"We":[47],"found":[48],"that,":[49],"as":[50,107,188,190],"expected,":[51],"non-regularized":[52,118],"correlations":[53,119],"had":[54],"low":[55,95],"variability":[56,123],"when":[57,124],"scarce":[59],"variables":[62,70],"were":[63,157],"considered.":[64],"slight":[67],"increase":[68,74],"led":[71],"an":[73],"variance":[76,96,199],"several":[78],"magnitude":[79],"orders.":[80],"On":[81],"other":[83],"hand,":[84],"regularized":[86,129],"approaches":[87],"showed":[88,121],"more":[89,142],"stable":[90],"results":[91],"with":[92,160,167,172],"relative":[94],"at":[97],"expense":[99],"little":[102],"bias.":[103],"Interestingly,":[104],"topological":[105],"properties":[106],"local":[108],"global":[110],"efficiency":[111],"estimated":[112],"networks":[114],"constructed":[115],"from":[116,128],"traditional":[117],"also":[120],"higher":[122],"compared":[125],"those":[127],"networks.":[130],"Our":[131],"findings":[132],"suggest":[133],"population-based":[136],"connectivity":[137],"study":[138],"achieve":[140],"robust":[143],"description":[144],"topology":[147],"through":[148],"estimates.":[153,206],"Four":[154],"methods":[156],"examined:":[158],"Two":[159],"shrinkage":[161,174],"(Ridge":[162],"Sch\u00e4fer\u2019s":[164],"shrinkage),":[165],"one":[166,171],"sparsity":[168,176],"(Lasso)":[169],"both":[173],"(Elastic":[177],"net).":[178],"Furthermore,":[179],"different":[181,185],"regularizations":[182],"resulted":[183,196],"estimates":[187,195,202],"well":[189],"network":[191],"properties.":[192],"shrunken":[194],"lower":[198],"than":[203],"sparse":[205]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}