{"id":"https://openalex.org/W2076933387","doi":"https://doi.org/10.1117/12.2042959","title":"Classification of normal and pathological aging processes based on brain MRI morphology measures","display_name":"Classification of normal and pathological aging processes based on brain MRI morphology measures","publication_year":2014,"publication_date":"2014-03-21","ids":{"openalex":"https://openalex.org/W2076933387","doi":"https://doi.org/10.1117/12.2042959","mag":"2076933387"},"language":"en","primary_location":{"id":"doi:10.1117/12.2042959","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2042959","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088852492","display_name":"Jorge P\u00e9rez-Gonz\u00e1lez","orcid":"https://orcid.org/0000-0002-4069-4268"},"institutions":[{"id":"https://openalex.org/I200362191","display_name":"Universidad Aut\u00f3noma Metropolitana","ror":"https://ror.org/02kta5139","country_code":"MX","type":"education","lineage":["https://openalex.org/I200362191"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"J. L. Perez-Gonzalez","raw_affiliation_strings":["Univ. Aut\u00f3noma Metropolitana (Mexico)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Aut\u00f3noma Metropolitana (Mexico)","institution_ids":["https://openalex.org/I200362191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053998821","display_name":"\u00d3scar Y\u00e1\u00f1ez-Su\u00e1rez","orcid":"https://orcid.org/0000-0002-4249-8877"},"institutions":[{"id":"https://openalex.org/I200362191","display_name":"Universidad Aut\u00f3noma Metropolitana","ror":"https://ror.org/02kta5139","country_code":"MX","type":"education","lineage":["https://openalex.org/I200362191"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"O. Yanez-Suarez","raw_affiliation_strings":["Univ. Aut\u00f3noma Metropolitana (Mexico)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Aut\u00f3noma Metropolitana (Mexico)","institution_ids":["https://openalex.org/I200362191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064600541","display_name":"Ver\u00f3nica Medina-Ba\u00f1uelos","orcid":"https://orcid.org/0000-0001-8072-3927"},"institutions":[{"id":"https://openalex.org/I200362191","display_name":"Universidad Aut\u00f3noma Metropolitana","ror":"https://ror.org/02kta5139","country_code":"MX","type":"education","lineage":["https://openalex.org/I200362191"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"V. Medina-Ba\u00f1uelos","raw_affiliation_strings":["Univ. Aut\u00f3noma Metropolitana (Mexico)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Aut\u00f3noma Metropolitana (Mexico)","institution_ids":["https://openalex.org/I200362191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.13778319,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"9034","issue":null,"first_page":"90341T","last_page":"90341T"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"Cognitive impairment","score":0.6229811310768127},{"id":"https://openalex.org/keywords/classification-scheme","display_name":"Classification scheme","score":0.5720159411430359},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5609092712402344},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5239277482032776},{"id":"https://openalex.org/keywords/pathological","display_name":"Pathological","score":0.5110977292060852},{"id":"https://openalex.org/keywords/brain-aging","display_name":"Brain aging","score":0.5015735626220703},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.47579774260520935},{"id":"https://openalex.org/keywords/brain-morphometry","display_name":"Brain morphometry","score":0.41208648681640625},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38667184114456177},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.37747615575790405},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3350057601928711},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.2917236089706421},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28332415223121643},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.24022048711776733},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.23248982429504395},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.1779768466949463},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.1767953634262085}],"concepts":[{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.6229811310768127},{"id":"https://openalex.org/C13460635","wikidata":"https://www.wikidata.org/wiki/Q85753676","display_name":"Classification scheme","level":2,"score":0.5720159411430359},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5609092712402344},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5239277482032776},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.5110977292060852},{"id":"https://openalex.org/C2993665655","wikidata":"https://www.wikidata.org/wiki/Q4692577","display_name":"Brain aging","level":3,"score":0.5015735626220703},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.47579774260520935},{"id":"https://openalex.org/C145940234","wikidata":"https://www.wikidata.org/wiki/Q4955830","display_name":"Brain morphometry","level":3,"score":0.41208648681640625},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38667184114456177},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.37747615575790405},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3350057601928711},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.2917236089706421},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28332415223121643},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.24022048711776733},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.23248982429504395},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.1779768466949463},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1767953634262085}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.2042959","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.2042959","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4300000071525574,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1837028288","https://openalex.org/W1983182638","https://openalex.org/W1983655753","https://openalex.org/W1984544413","https://openalex.org/W1994694375","https://openalex.org/W2014915963","https://openalex.org/W2020281498","https://openalex.org/W2033448370","https://openalex.org/W2086316204","https://openalex.org/W2095647323","https://openalex.org/W2171196057","https://openalex.org/W2171225117","https://openalex.org/W2549067159","https://openalex.org/W4387567295","https://openalex.org/W6638699964","https://openalex.org/W6638732700","https://openalex.org/W6658898263"],"related_works":["https://openalex.org/W2090763504","https://openalex.org/W148178222","https://openalex.org/W2104657898","https://openalex.org/W3108783315","https://openalex.org/W4287587859","https://openalex.org/W2793875659","https://openalex.org/W181901431","https://openalex.org/W4212824314","https://openalex.org/W2896165108","https://openalex.org/W2245796482"],"abstract_inverted_index":{"Reported":[0],"studies":[1],"describing":[2],"normal":[3],"and":[4,37,57,67,88,94,109,115,117,122,133],"abnormal":[5],"aging":[6,47,145],"based":[7,33],"on":[8,35],"anatomical":[9,96],"MRI":[10],"analysis":[11,99],"do":[12],"not":[13],"consider":[14],"morphological":[15,140],"brain":[16,42],"changes,":[17],"but":[18],"only":[19],"volumetric":[20],"measures":[21,87],"to":[22,44,105,142],"distinguish":[23],"among":[24],"these":[25,74],"processes.":[26],"This":[27],"work":[28],"presents":[29],"a":[30,81],"classification":[31,101],"scheme,":[32],"both":[34],"size":[36],"shape":[38],"features":[39,79],"extracted":[40],"from":[41,80],"volumes,":[43],"determine":[45],"different":[46,144],"stages:":[48],"healthy":[49],"control":[50],"(HC)":[51],"adults,":[52],"mild":[53],"cognitive":[54],"impairment":[55],"(MCI),":[56],"Alzheimer's":[58],"disease":[59],"(AD).":[60],"Three":[61],"support":[62],"vector":[63],"machines":[64],"were":[65],"optimized":[66],"validated":[68],"for":[69,120],"the":[70,131,135,138],"pair-wise":[71],"separation":[72],"of":[73,83,91,103,111,118,137],"three":[75],"classes,":[76],"using":[77],"selected":[78],"set":[82],"3D":[84],"discrete":[85],"compactness":[86],"normalized":[89],"volumes":[90],"several":[92],"global":[93],"local":[95],"structures.":[97],"Our":[98],"show":[100],"rates":[102],"up":[104],"98.3%":[106],"between":[107,113],"HC":[108,114],"AD;":[110],"85%":[112],"MCI":[116,121],"93.3%":[119],"AD":[123],"separation.":[124],"These":[125],"results":[126],"outperform":[127],"those":[128],"reported":[129],"in":[130],"literature":[132],"demonstrate":[134],"viability":[136],"proposed":[139],"indexes":[141],"classify":[143],"stages.":[146]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}