{"id":"https://openalex.org/W2148120777","doi":"https://doi.org/10.1109/tbme.2009.2023978","title":"Biophysical Model of an Auditory Nerve Fiber With a Novel Adaptation Component","display_name":"Biophysical Model of an Auditory Nerve Fiber With a Novel Adaptation Component","publication_year":2009,"publication_date":"2009-06-02","ids":{"openalex":"https://openalex.org/W2148120777","doi":"https://doi.org/10.1109/tbme.2009.2023978","mag":"2148120777","pmid":"https://pubmed.ncbi.nlm.nih.gov/19497810"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2009.2023978","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2009.2023978","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077081621","display_name":"Jihwan Woo","orcid":"https://orcid.org/0000-0003-2227-5948"},"institutions":[{"id":"https://openalex.org/I2802216851","display_name":"University of Iowa Hospitals and Clinics","ror":"https://ror.org/04g2swc55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I126307644","https://openalex.org/I2802216851"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jihwan Woo","raw_affiliation_strings":["Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA. jihwan-woo@uiowa.edu","Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA. jihwan-woo@uiowa.edu","institution_ids":["https://openalex.org/I2802216851"]},{"raw_affiliation_string":"Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA","institution_ids":["https://openalex.org/I2802216851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052202815","display_name":"Charles A. Miller","orcid":"https://orcid.org/0000-0002-3813-1706"},"institutions":[{"id":"https://openalex.org/I2802216851","display_name":"University of Iowa Hospitals and Clinics","ror":"https://ror.org/04g2swc55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I126307644","https://openalex.org/I2802216851"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.A. Miller","raw_affiliation_strings":["University of Iowa Hospitals and Clinics, Iowa City, IA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Iowa Hospitals and Clinics, Iowa City, IA, US","institution_ids":["https://openalex.org/I2802216851"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110219076","display_name":"Paul J. Abbas","orcid":null},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]},{"id":"https://openalex.org/I2802216851","display_name":"University of Iowa Hospitals and Clinics","ror":"https://ror.org/04g2swc55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I126307644","https://openalex.org/I2802216851"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P.J. Abbas","raw_affiliation_strings":["Department of Communication Sciences and Disorders, Iowa City, IA, USA","Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Communication Sciences and Disorders, Iowa City, IA, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA","institution_ids":["https://openalex.org/I2802216851"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":0.9256,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.6959152,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"56","issue":"9","first_page":"2177","last_page":"2180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.5928072333335876},{"id":"https://openalex.org/keywords/neural-adaptation","display_name":"Neural adaptation","score":0.5544393658638},{"id":"https://openalex.org/keywords/neural-coding","display_name":"Neural coding","score":0.5265191793441772},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.5222724080085754},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.4876314699649811},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.47039708495140076},{"id":"https://openalex.org/keywords/adaptation","display_name":"Adaptation (eye)","score":0.4663526117801666},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4539201259613037},{"id":"https://openalex.org/keywords/coding","display_name":"Coding (social sciences)","score":0.4496241509914398},{"id":"https://openalex.org/keywords/axon","display_name":"Axon","score":0.4357859194278717},{"id":"https://openalex.org/keywords/pulse","display_name":"Pulse (music)","score":0.41817963123321533},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.35000425577163696},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.22842195630073547},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1879333257675171},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17431721091270447},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.13190147280693054},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.0998682975769043}],"concepts":[{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.5928072333335876},{"id":"https://openalex.org/C2780112520","wikidata":"https://www.wikidata.org/wiki/Q5353379","display_name":"Neural adaptation","level":3,"score":0.5544393658638},{"id":"https://openalex.org/C77637269","wikidata":"https://www.wikidata.org/wiki/Q7002051","display_name":"Neural coding","level":2,"score":0.5265191793441772},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.5222724080085754},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4876314699649811},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.47039708495140076},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.4663526117801666},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4539201259613037},{"id":"https://openalex.org/C179518139","wikidata":"https://www.wikidata.org/wiki/Q5140297","display_name":"Coding (social sciences)","level":2,"score":0.4496241509914398},{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.4357859194278717},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.41817963123321533},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.35000425577163696},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.22842195630073547},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1879333257675171},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17431721091270447},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.13190147280693054},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0998682975769043},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000222","descriptor_name":"Adaptation, Physiological","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003056","descriptor_name":"Cochlear Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003056","descriptor_name":"Cochlear Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003056","descriptor_name":"Cochlear Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009412","descriptor_name":"Nerve Fibers","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009412","descriptor_name":"Nerve Fibers","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009412","descriptor_name":"Nerve Fibers","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2009.2023978","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2009.2023978","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:19497810","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19497810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on bio-medical engineering","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1031194793","display_name":null,"funder_award_id":"R01-DC006478","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"}],"funders":[{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1972912532","https://openalex.org/W1974303879","https://openalex.org/W2019484205","https://openalex.org/W2038914534","https://openalex.org/W2052565271","https://openalex.org/W2067496236","https://openalex.org/W2068146904","https://openalex.org/W2087129686","https://openalex.org/W2088433902","https://openalex.org/W2091829257","https://openalex.org/W2142599470","https://openalex.org/W2148120777","https://openalex.org/W2156176478"],"related_works":["https://openalex.org/W2915014248","https://openalex.org/W2122884624","https://openalex.org/W2127637679","https://openalex.org/W2411152067","https://openalex.org/W2044871842","https://openalex.org/W3027967615","https://openalex.org/W2065031478","https://openalex.org/W3093191726","https://openalex.org/W2976721600","https://openalex.org/W2945852810"],"abstract_inverted_index":{"Recent":[0],"data":[1],"from":[2],"feline":[3],"auditory":[4,32],"nerve":[5],"fibers":[6,12],"(ANFs)":[7],"indicate":[8],"that":[9,66,75,97],"electrically":[10],"stimulated":[11],"can":[13],"undergo":[14],"large":[15],"degrees":[16],"of":[17,37,53,60,120],"rate":[18],"adaptation":[19],"to":[20,100,114],"pulse-train":[21],"stimuli":[22],"using":[23],"pulse":[24],"rates":[25],"within":[26],"the":[27,35,51,121],"range":[28],"used":[29],"by":[30,81,125],"clinical":[31],"prostheses.":[33],"However,":[34],"application":[36],"Hodgkin-Huxley-type":[38],"models":[39,113],"does":[40],"not":[41],"produce":[42,115],"such":[43],"adaptation,":[44],"which":[45],"occurs":[46],"over":[47],"time":[48,95],"periods":[49],"on":[50,77],"order":[52],"100":[54],"ms.":[55],"We":[56],"describe":[57],"our":[58],"development":[59],"a":[61,68],"computational":[62],"ANF":[63],"axon":[64],"model":[65],"incorporates":[67],"time-changing":[69],"external":[70],"potassium":[71,78],"concentration":[72],"(":[73],"[K(+)](ext))":[74],"depends":[76],"currents":[79],"produced":[80,124],"active":[82],"nodal":[83],"channel":[84],"activity.":[85],"This":[86],"relatively":[87],"simple":[88],"and":[89],"computationally":[90],"tractable":[91],"approach":[92],"produces":[93],"poststimulus":[94],"histograms":[96],"are":[98],"similar":[99],"experimental":[101],"(cat)":[102],"data.":[103],"Furthermore,":[104],"this":[105],"mechanism":[106],"could":[107],"be":[108],"easily":[109],"incorporated":[110],"into":[111],"other":[112],"much":[116],"more":[117],"realistic":[118],"estimates":[119],"neural":[122],"coding":[123],"repeated":[126],"electric":[127],"stimulation.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}