{"id":"https://openalex.org/W4417473040","doi":"https://doi.org/10.1109/sipaim67325.2025.11283374","title":"Macular Edema Classification using an Evolutionary Binary Regular Expression Strategy","display_name":"Macular Edema Classification using an Evolutionary Binary Regular Expression Strategy","publication_year":2025,"publication_date":"2025-11-18","ids":{"openalex":"https://openalex.org/W4417473040","doi":"https://doi.org/10.1109/sipaim67325.2025.11283374"},"language":null,"primary_location":{"id":"doi:10.1109/sipaim67325.2025.11283374","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sipaim67325.2025.11283374","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5115407489","display_name":"Rafael A. Garc\u00eda-Ram\u00edrez","orcid":null},"institutions":[{"id":"https://openalex.org/I4210120064","display_name":"Centro Medico Nacional Siglo XXI","ror":"https://ror.org/02vz80y09","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I164915025","https://openalex.org/I4210120064"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Rafael A. Garc\u00eda-Ram\u00edrez","raw_affiliation_strings":["Centro de Investigación en Matemáticas,Gto,Mexico"],"affiliations":[{"raw_affiliation_string":"Centro de Investigación en Matemáticas,Gto,Mexico","institution_ids":["https://openalex.org/I4210120064"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115407490","display_name":"Ulises A. Gonzalez-Valadez","orcid":null},"institutions":[{"id":"https://openalex.org/I4210120064","display_name":"Centro Medico Nacional Siglo XXI","ror":"https://ror.org/02vz80y09","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I164915025","https://openalex.org/I4210120064"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ulises A. Gonzalez-Valadez","raw_affiliation_strings":["Centro de Investigación en Matemáticas,Gto,Mexico"],"affiliations":[{"raw_affiliation_string":"Centro de Investigación en Matemáticas,Gto,Mexico","institution_ids":["https://openalex.org/I4210120064"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002283995","display_name":"Ivan Cruz\u2010Aceves","orcid":"https://orcid.org/0000-0002-5197-2059"},"institutions":[{"id":"https://openalex.org/I4210120064","display_name":"Centro Medico Nacional Siglo XXI","ror":"https://ror.org/02vz80y09","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I164915025","https://openalex.org/I4210120064"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ivan Cruz-Aceves","raw_affiliation_strings":["SECIHTI-Centro de Investigación en Matemáticas,Gto,Mexico"],"affiliations":[{"raw_affiliation_string":"SECIHTI-Centro de Investigación en Matemáticas,Gto,Mexico","institution_ids":["https://openalex.org/I4210120064"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044004032","display_name":"Arturo Hern\u00e1ndez-Aguirre","orcid":"https://orcid.org/0000-0002-3744-9827"},"institutions":[{"id":"https://openalex.org/I4210120064","display_name":"Centro Medico Nacional Siglo XXI","ror":"https://ror.org/02vz80y09","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I164915025","https://openalex.org/I4210120064"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Arturo Hern\u00e1ndez-Aguirre","raw_affiliation_strings":["Centro de Investigación en Matemáticas,Gto,Mexico"],"affiliations":[{"raw_affiliation_string":"Centro de Investigación en Matemáticas,Gto,Mexico","institution_ids":["https://openalex.org/I4210120064"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061738550","display_name":"Gloria Paulina Trujillo-S\u00e1nchez","orcid":"https://orcid.org/0000-0002-1810-9587"},"institutions":[{"id":"https://openalex.org/I4210136171","display_name":"Hospital de Especialidades","ror":"https://ror.org/04f86t017","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210136171"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Gloria P. Trujillo-S\u00e1nchez","raw_affiliation_strings":["Unidad Médica de Alta Especialidad Hospital de Especialidades No. 1 IMSS, León,México"],"affiliations":[{"raw_affiliation_string":"Unidad Médica de Alta Especialidad Hospital de Especialidades No. 1 IMSS, León,México","institution_ids":["https://openalex.org/I4210136171"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025299046","display_name":"Martha Alicia Hern\u00e1ndez-Gonzalez","orcid":"https://orcid.org/0000-0002-6903-2233"},"institutions":[{"id":"https://openalex.org/I4210136171","display_name":"Hospital de Especialidades","ror":"https://ror.org/04f86t017","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210136171"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Martha A. Hernandez-Gonz\u00e1lez","raw_affiliation_strings":["Unidad Médica de Alta Especialidad Hospital de Especialidades No. 1 IMSS, León,México"],"affiliations":[{"raw_affiliation_string":"Unidad Médica de Alta Especialidad Hospital de Especialidades No. 1 IMSS, León,México","institution_ids":["https://openalex.org/I4210136171"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5115407489"],"corresponding_institution_ids":["https://openalex.org/I4210120064"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.58303685,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6363999843597412},{"id":"https://openalex.org/keywords/binary-classification","display_name":"Binary classification","score":0.5468000173568726},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.5189999938011169},{"id":"https://openalex.org/keywords/drusen","display_name":"Drusen","score":0.4657999873161316},{"id":"https://openalex.org/keywords/binary-number","display_name":"Binary number","score":0.40389999747276306},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.3686999976634979},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.3626999855041504},{"id":"https://openalex.org/keywords/cotton-wool-spots","display_name":"Cotton wool spots","score":0.34209999442100525}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7172999978065491},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6363999843597412},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5708000063896179},{"id":"https://openalex.org/C66905080","wikidata":"https://www.wikidata.org/wiki/Q17005494","display_name":"Binary classification","level":3,"score":0.5468000173568726},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.5189999938011169},{"id":"https://openalex.org/C2779093074","wikidata":"https://www.wikidata.org/wiki/Q1140528","display_name":"Drusen","level":3,"score":0.4657999873161316},{"id":"https://openalex.org/C48372109","wikidata":"https://www.wikidata.org/wiki/Q3913","display_name":"Binary number","level":2,"score":0.40389999747276306},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.3686999976634979},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.3626999855041504},{"id":"https://openalex.org/C2776689232","wikidata":"https://www.wikidata.org/wiki/Q5175762","display_name":"Cotton wool spots","level":4,"score":0.34209999442100525},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.32100000977516174},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.3199999928474426},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.3059999942779541},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.3012000024318695},{"id":"https://openalex.org/C196070930","wikidata":"https://www.wikidata.org/wiki/Q598190","display_name":"Correlogram","level":2,"score":0.2928999960422516},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.29089999198913574},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.28929999470710754},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.28189998865127563},{"id":"https://openalex.org/C2776391266","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Fundus (uterus)","level":2,"score":0.26759999990463257}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/sipaim67325.2025.11283374","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sipaim67325.2025.11283374","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1775135849","https://openalex.org/W1915008606","https://openalex.org/W2120538351","https://openalex.org/W3083256970","https://openalex.org/W3158522809","https://openalex.org/W3174393927","https://openalex.org/W3191934798","https://openalex.org/W4366281042","https://openalex.org/W4396899928","https://openalex.org/W4400085415","https://openalex.org/W4400484402","https://openalex.org/W4401178894","https://openalex.org/W4409622135","https://openalex.org/W4409797536"],"related_works":[],"abstract_inverted_index":{"This":[0],"paper":[1],"presents":[2],"a":[3,45,52,70,82,88,101,116,129],"new":[4],"approach":[5],"for":[6,65,135],"the":[7,32,37,78,98],"classification":[8,102,137],"of":[9,36,60,104,110,118],"macular":[10],"edema":[11],"types":[12],"in":[13],"low-resolution":[14,140],"retinal":[15],"fundus":[16],"images.":[17,38,141],"The":[18],"proposed":[19],"method":[20,99],"moves":[21],"away":[22],"from":[23],"traditional":[24],"spatial-based":[25],"techniques":[26],"and":[27,50,69,93,106,132],"instead":[28],"operates":[29],"directly":[30],"on":[31,87,139],"raw":[33],"byte-stream":[34],"representation":[35],"An":[39],"evolutionary":[40],"framework":[41],"is":[42,58,128],"employed,":[43],"utilizing":[44],"genetic":[46],"algorithm":[47],"to":[48,81],"discover":[49],"optimize":[51],"two-stage":[53],"binary":[54],"classifier.":[55],"Each":[56],"classifier":[57],"composed":[59],"an":[61,107],"evolved":[62],"regular":[63],"expression":[64],"byte-level":[66,125],"pattern":[67],"matching,":[68],"subsequent":[71],"Binary":[72],"Trainable":[73],"Decision":[74],"Function":[75],"that":[76,124],"maps":[77],"matched":[79],"sequence":[80],"final":[83],"class":[84],"label.":[85],"Evaluated":[86],"hand-labeled":[89],"dataset":[90],"containing":[91],"Drusen":[92],"Cotton":[94],"Wool":[95],"Spot-Type":[96],"edema,":[97],"achieved":[100],"accuracy":[103],"0.9535":[105],"F1":[108],"Score":[109],"0.9286.":[111],"These":[112],"results":[113],"significantly":[114],"outperform":[115],"suite":[117],"state-of-the-art":[119],"deep":[120],"learning":[121],"models,":[122],"demonstrating":[123],"feature":[126],"discovery":[127],"highly":[130],"effective":[131],"competitive":[133],"strategy":[134],"biomedical":[136],"task":[138]},"counts_by_year":[],"updated_date":"2026-03-07T16:01:11.037858","created_date":"2025-12-18T00:00:00"}