{"id":"https://openalex.org/W2561538108","doi":"https://doi.org/10.1109/nems.2016.7758320","title":"Miniaturized electrochemical sensor modified with aptamers for rapid norovirus detection","display_name":"Miniaturized electrochemical sensor modified with aptamers for rapid norovirus detection","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W2561538108","doi":"https://doi.org/10.1109/nems.2016.7758320","mag":"2561538108"},"language":"en","primary_location":{"id":"doi:10.1109/nems.2016.7758320","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2016.7758320","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/1721.1/110673","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100772496","display_name":"Nan Wang","orcid":"https://orcid.org/0000-0001-5165-0861"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Nan Wang","raw_affiliation_strings":["Nanyang Technological University, Avenue, Singapore"],"affiliations":[{"raw_affiliation_string":"Nanyang Technological University, Avenue, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050896717","display_name":"Masaaki Kitajima","orcid":"https://orcid.org/0000-0002-8142-511X"},"institutions":[{"id":"https://openalex.org/I4210167254","display_name":"Singapore-MIT Alliance for Research and Technology","ror":"https://ror.org/05yb3w112","country_code":"SG","type":"education","lineage":["https://openalex.org/I4210167254"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Masaaki Kitajima","raw_affiliation_strings":["Singapore-MIT Alliance for Research and Technology (SMART), Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore-MIT Alliance for Research and Technology (SMART), Singapore","institution_ids":["https://openalex.org/I4210167254"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112313498","display_name":"Kalaivani Mani","orcid":null},"institutions":[{"id":"https://openalex.org/I4210167254","display_name":"Singapore-MIT Alliance for Research and Technology","ror":"https://ror.org/05yb3w112","country_code":"SG","type":"education","lineage":["https://openalex.org/I4210167254"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kalaivani Mani","raw_affiliation_strings":["Singapore-MIT Alliance for Research and Technology (SMART), Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore-MIT Alliance for Research and Technology (SMART), Singapore","institution_ids":["https://openalex.org/I4210167254"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043626030","display_name":"Elgar Kanhere","orcid":"https://orcid.org/0000-0002-9416-0931"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Elgar Kanhere","raw_affiliation_strings":["Nanyang Technological University, Avenue, Singapore"],"affiliations":[{"raw_affiliation_string":"Nanyang Technological University, Avenue, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108357281","display_name":"Andrew J. Whittle","orcid":null},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew J. Whittle","raw_affiliation_strings":["Massachusetts Institute of Technology, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111484618","display_name":"Michael S. Triantafyllou","orcid":null},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Michael S. Triantafyllou","raw_affiliation_strings":["Nanyang Technological University, Avenue, Singapore"],"affiliations":[{"raw_affiliation_string":"Nanyang Technological University, Avenue, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113521751","display_name":"Jianmin Miao","orcid":null},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jianmin Miao","raw_affiliation_strings":["Nanyang Technological University, Avenue, Singapore"],"affiliations":[{"raw_affiliation_string":"Nanyang Technological University, Avenue, Singapore","institution_ids":["https://openalex.org/I172675005"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5100772496"],"corresponding_institution_ids":["https://openalex.org/I172675005"],"apc_list":null,"apc_paid":null,"fwci":1.338,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.81206763,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"587","last_page":"590"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.9710999727249146,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aptamer","display_name":"Aptamer","score":0.9447053670883179},{"id":"https://openalex.org/keywords/norovirus","display_name":"Norovirus","score":0.747803807258606},{"id":"https://openalex.org/keywords/microelectromechanical-systems","display_name":"Microelectromechanical systems","score":0.581030547618866},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5008945465087891},{"id":"https://openalex.org/keywords/lab-on-a-chip","display_name":"Lab-on-a-chip","score":0.4785243272781372},{"id":"https://openalex.org/keywords/electrochemical-gas-sensor","display_name":"Electrochemical gas sensor","score":0.457555890083313},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.4357993006706238},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.325135201215744},{"id":"https://openalex.org/keywords/electrochemistry","display_name":"Electrochemistry","score":0.25350821018218994},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.17707353830337524},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.17623227834701538},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.13890990614891052},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.13103502988815308},{"id":"https://openalex.org/keywords/molecular-biology","display_name":"Molecular biology","score":0.06988024711608887},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.058934688568115234}],"concepts":[{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.9447053670883179},{"id":"https://openalex.org/C2778750513","wikidata":"https://www.wikidata.org/wiki/Q1142751","display_name":"Norovirus","level":3,"score":0.747803807258606},{"id":"https://openalex.org/C37977207","wikidata":"https://www.wikidata.org/wiki/Q175561","display_name":"Microelectromechanical systems","level":2,"score":0.581030547618866},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5008945465087891},{"id":"https://openalex.org/C138942068","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Lab-on-a-chip","level":3,"score":0.4785243272781372},{"id":"https://openalex.org/C188095982","wikidata":"https://www.wikidata.org/wiki/Q5357970","display_name":"Electrochemical gas sensor","level":4,"score":0.457555890083313},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4357993006706238},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.325135201215744},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.25350821018218994},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.17707353830337524},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.17623227834701538},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.13890990614891052},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13103502988815308},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.06988024711608887},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.058934688568115234},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/nems.2016.7758320","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nems.2016.7758320","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","raw_type":"proceedings-article"},{"id":"pmh:oai:dspace.mit.edu:1721.1/110673","is_oa":true,"landing_page_url":"http://hdl.handle.net/1721.1/110673","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Prof. Triantafyllou via Angie Locknar","raw_type":"http://purl.org/eprint/type/ConferencePaper"}],"best_oa_location":{"id":"pmh:oai:dspace.mit.edu:1721.1/110673","is_oa":true,"landing_page_url":"http://hdl.handle.net/1721.1/110673","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Prof. Triantafyllou via Angie Locknar","raw_type":"http://purl.org/eprint/type/ConferencePaper"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1916445935","https://openalex.org/W1992450042","https://openalex.org/W2037966713","https://openalex.org/W2062791268","https://openalex.org/W2132969117","https://openalex.org/W2135614629","https://openalex.org/W6640240458"],"related_works":["https://openalex.org/W2967136651","https://openalex.org/W2033684641","https://openalex.org/W2913646003","https://openalex.org/W2081632393","https://openalex.org/W2147509954","https://openalex.org/W1970773045","https://openalex.org/W4389944751","https://openalex.org/W3092671456","https://openalex.org/W2898457449","https://openalex.org/W2566736735"],"abstract_inverted_index":{"This":[0,88],"paper":[1],"presents":[2],"a":[3,40,83],"miniaturized":[4,41],"MEMS":[5,67],"(microelectromechanical":[6],"systems)-based":[7],"electrochemical":[8,44,68,98],"aptasensor,":[9],"which":[10],"utilizes":[11],"aptamer":[12],"as":[13],"the":[14,62,65,94],"recognition":[15],"element":[16],"for":[17,46,93,104],"simple,":[18],"sensitive":[19],"and":[20,42,55,61,101],"rapid":[21],"detection":[22],"of":[23,27,32,64,80,85,96],"norovirus.":[24,87],"The":[25,50],"novelty":[26],"this":[28],"work":[29],"is":[30],"integration":[31],"micro":[33],"fabrication":[34],"technology":[35],"with":[36,72],"aptamers":[37,54],"to":[38,74,77],"develop":[39],"portable":[43],"sensor":[45,75],"environmental":[47],"pathogen":[48],"monitoring.":[49],"binding":[51],"capability":[52],"between":[53],"on-chip":[56],"sensing":[57],"electrodes":[58],"was":[59,70],"investigated":[60],"performance":[63],"proposed":[66],"aptasensor":[69],"evaluated":[71],"respect":[73],"response":[76],"different":[78],"titers":[79],"murine":[81],"norovirus,":[82],"model":[84],"human":[86],"research":[89],"forms":[90],"initial":[91],"basis":[92],"development":[95],"an":[97],"MEMS-aptasensor":[99],"platform":[100],"its":[102],"application":[103],"virus":[105],"detection.":[106]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}