{"id":"https://openalex.org/W2140494767","doi":"https://doi.org/10.1109/isda.2006.154","title":"From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway","display_name":"From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway","publication_year":2006,"publication_date":"2006-10-01","ids":{"openalex":"https://openalex.org/W2140494767","doi":"https://doi.org/10.1109/isda.2006.154","mag":"2140494767"},"language":"en","primary_location":{"id":"doi:10.1109/isda.2006.154","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isda.2006.154","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sixth International Conference on Intelligent Systems Design and Applications","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023019126","display_name":"Sandhya R. Shenoy","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Sandhya Shenoy","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050472519","display_name":"Poonam Singhal","orcid":"https://orcid.org/0000-0001-6828-5039"},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Poonam Singhal","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109701676","display_name":"A. Gandhimathi","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"A. Gandhimathi","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091701857","display_name":"Praveen Agrawal","orcid":"https://orcid.org/0000-0002-8892-9169"},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Praveen Agrawal","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034487180","display_name":"Vidhu Pandey","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vidhu Pandey","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001713925","display_name":"Samrat Dutta","orcid":"https://orcid.org/0000-0002-0825-8589"},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Samrat Dutta","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001772301","display_name":"Gurvisha Sandhu","orcid":null},"institutions":[{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]},{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Gurvisha Sandhu","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101599268","display_name":"Anuj Gupta","orcid":"https://orcid.org/0000-0001-7010-2836"},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anuj Gupta","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112232196","display_name":"Shashank Shekhar","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shashank Shekhar","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103047628","display_name":"Shailesh Tripathi","orcid":"https://orcid.org/0000-0002-3484-6368"},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shailesh Tripathi","raw_affiliation_strings":["Department of Chemistry & Supercomputing Facility for Bioinformatics & Computational Biology, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry & Supercomputing Facility for Bioinformatics & Computational Biology, Indian Institute of Technology, New Delhi, India","institution_ids":[]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043437093","display_name":"B. Jayaram","orcid":"https://orcid.org/0000-0002-5495-2213"},"institutions":[{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]},{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"B. Jayaram","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111940238","display_name":"N. Latha","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"N. Latha","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111692876","display_name":"Pooja Narang","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pooja Narang","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023336187","display_name":"Tarun Jain","orcid":"https://orcid.org/0000-0002-4330-1845"},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tarun Jain","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073442658","display_name":"Kumkum Bhushan","orcid":null},"institutions":[{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]},{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kumkum Bhushan","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066994153","display_name":"Saher A. Shaikh","orcid":"https://orcid.org/0000-0002-6162-5472"},"institutions":[{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]},{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Saher Afshan Shaikh","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023981536","display_name":"Surojit Bose","orcid":null},"institutions":[{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]},{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Surojit Bose","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101574091","display_name":"Pankaj Sharma","orcid":"https://orcid.org/0000-0002-2948-4075"},"institutions":[{"id":"https://openalex.org/I68891433","display_name":"Indian Institute of Technology Delhi","ror":"https://ror.org/049tgcd06","country_code":"IN","type":"education","lineage":["https://openalex.org/I68891433"]},{"id":"https://openalex.org/I64295750","display_name":"Indian Institute of Technology Indore","ror":"https://ror.org/01hhf7w52","country_code":"IN","type":"education","lineage":["https://openalex.org/I64295750"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pankaj Sharma","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, New Delhi, India","Indian Institute of Technology  (India)"],"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, New Delhi, India","institution_ids":["https://openalex.org/I68891433"]},{"raw_affiliation_string":"Indian Institute of Technology  (India)","institution_ids":["https://openalex.org/I64295750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":18,"corresponding_author_ids":["https://openalex.org/A5023019126"],"corresponding_institution_ids":["https://openalex.org/I64295750","https://openalex.org/I68891433"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.13322078,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"303","issue":null,"first_page":"1147","last_page":"1152"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9912999868392944,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6389479637145996},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.5630440711975098},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5514947175979614},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.49996042251586914},{"id":"https://openalex.org/keywords/grid","display_name":"Grid","score":0.42975327372550964},{"id":"https://openalex.org/keywords/modelling-biological-systems","display_name":"Modelling biological systems","score":0.4199954569339752},{"id":"https://openalex.org/keywords/grid-computing","display_name":"Grid computing","score":0.41696614027023315},{"id":"https://openalex.org/keywords/field","display_name":"Field (mathematics)","score":0.4167836606502533},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3714253902435303},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.35273462533950806},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.34651994705200195},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.29572585225105286},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2786145508289337},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1162179708480835},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.08903524279594421}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6389479637145996},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.5630440711975098},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5514947175979614},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.49996042251586914},{"id":"https://openalex.org/C187691185","wikidata":"https://www.wikidata.org/wiki/Q2020720","display_name":"Grid","level":2,"score":0.42975327372550964},{"id":"https://openalex.org/C137866125","wikidata":"https://www.wikidata.org/wiki/Q4299308","display_name":"Modelling biological systems","level":3,"score":0.4199954569339752},{"id":"https://openalex.org/C70429105","wikidata":"https://www.wikidata.org/wiki/Q249999","display_name":"Grid computing","level":3,"score":0.41696614027023315},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.4167836606502533},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3714253902435303},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.35273462533950806},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34651994705200195},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29572585225105286},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2786145508289337},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1162179708480835},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08903524279594421},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isda.2006.154","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isda.2006.154","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sixth International Conference on Intelligent Systems Design and Applications","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.489.1705","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.489.1705","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.scfbio-iitd.res.in/doc/IEEE.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.5}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1978164115","https://openalex.org/W1998618677","https://openalex.org/W2027981873","https://openalex.org/W2050273205","https://openalex.org/W2074630481","https://openalex.org/W2088808692","https://openalex.org/W2104765598","https://openalex.org/W2112502447","https://openalex.org/W2130259216","https://openalex.org/W2135129569","https://openalex.org/W2137822079","https://openalex.org/W2171943984","https://openalex.org/W2215564679","https://openalex.org/W6663213897"],"related_works":["https://openalex.org/W1824707887","https://openalex.org/W2068583628","https://openalex.org/W169905258","https://openalex.org/W1570043218","https://openalex.org/W3146449452","https://openalex.org/W2162684709","https://openalex.org/W2115770466","https://openalex.org/W2111726532","https://openalex.org/W2083893056","https://openalex.org/W2085955872"],"abstract_inverted_index":{"The":[0],"last":[1],"decade":[2],"has":[3],"witnessed":[4],"an":[5,41,75,81],"exponential":[6],"growth":[7],"of":[8,14,46,83,86,103],"sequence":[9],"information":[10,37],"in":[11,52,77,95],"the":[12,53,110,130],"field":[13],"biological":[15],"macromolecules":[16],"such":[17,36],"as":[18],"proteins":[19],"and":[20,23,43,80,91,116,120,136],"nucleic":[21],"acids":[22],"their":[24,92],"interactions":[25],"with":[26],"other":[27],"molecules.":[28],"Computational":[29],"analyses":[30],"for":[31],"structure-function":[32],"predictions":[33],"based":[34],"on":[35],"are":[38,68],"increasingly":[39],"becoming":[40],"essential":[42],"integral":[44],"part":[45],"modern":[47],"biology.":[48],"With":[49],"rapid":[50],"advances":[51],"area,":[54],"there":[55],"is":[56,74],"a":[57,101],"growing":[58],"need":[59],"to":[60,72,100,114,128],"develop":[61],"efficient":[62],"versatile":[63],"bioinformatics":[64,104],"software":[65],"packages,":[66],"which":[67],"hypothesis":[69],"driven.":[70],"'Gene":[71],"Drug'":[73],"attempt":[76],"this":[78],"pursuit":[79],"integration":[82],"heterologous":[84],"applications":[85],"different":[87],"technologies":[88],"developed":[89],"in-house":[90],"translation":[93],"into":[94],"silico":[96],"products":[97],"that":[98],"cater":[99],"majority":[102],"applications.":[105],"This":[106],"paper":[107],"briefly":[108],"presents":[109],"science":[111],"behind":[112],"gene":[113],"drug":[115],"how":[117],"grid":[118],"services":[119],"high":[121],"performance":[122],"computing":[123],"platforms":[124],"can":[125],"be":[126],"harnessed":[127],"bridge":[129],"gap":[131],"between":[132],"biomolecular":[133],"sequence,":[134],"structure":[135],"function":[137]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}