{"id":"https://openalex.org/W4416251125","doi":"https://doi.org/10.1109/ijcnn64981.2025.11229023","title":"Genetic Predictors of Social and Cognitive Outcomes in People with Ultra-High-Risk of Psychosis Using Spiking Neural Networks","display_name":"Genetic Predictors of Social and Cognitive Outcomes in People with Ultra-High-Risk of Psychosis Using Spiking Neural Networks","publication_year":2025,"publication_date":"2025-06-30","ids":{"openalex":"https://openalex.org/W4416251125","doi":"https://doi.org/10.1109/ijcnn64981.2025.11229023"},"language":null,"primary_location":{"id":"doi:10.1109/ijcnn64981.2025.11229023","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ijcnn64981.2025.11229023","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 International Joint Conference on Neural Networks (IJCNN)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090783596","display_name":"Zohreh Doborjeh","orcid":"https://orcid.org/0000-0003-1431-8258"},"institutions":[{"id":"https://openalex.org/I39854758","display_name":"Auckland University of Technology","ror":"https://ror.org/01zvqw119","country_code":"NZ","type":"education","lineage":["https://openalex.org/I39854758"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Zohreh Doborjeh","raw_affiliation_strings":["Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand"],"affiliations":[{"raw_affiliation_string":"Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand","institution_ids":["https://openalex.org/I39854758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112625201","display_name":"Balkaran Singh","orcid":null},"institutions":[{"id":"https://openalex.org/I39854758","display_name":"Auckland University of Technology","ror":"https://ror.org/01zvqw119","country_code":"NZ","type":"education","lineage":["https://openalex.org/I39854758"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Balkaran Singh","raw_affiliation_strings":["Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand"],"affiliations":[{"raw_affiliation_string":"Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand","institution_ids":["https://openalex.org/I39854758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011765174","display_name":"Alexander Sumich","orcid":"https://orcid.org/0000-0003-4333-8442"},"institutions":[{"id":"https://openalex.org/I52590639","display_name":"Nottingham Trent University","ror":"https://ror.org/04xyxjd90","country_code":"GB","type":"education","lineage":["https://openalex.org/I52590639"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexander Sumich","raw_affiliation_strings":["Nottingham Trent University,NTU Psychology, School of Social Sciences,Nottingham,United Kingdom"],"affiliations":[{"raw_affiliation_string":"Nottingham Trent University,NTU Psychology, School of Social Sciences,Nottingham,United Kingdom","institution_ids":["https://openalex.org/I52590639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008184865","display_name":"Maryam Doborjeh","orcid":"https://orcid.org/0000-0003-4953-0662"},"institutions":[{"id":"https://openalex.org/I39854758","display_name":"Auckland University of Technology","ror":"https://ror.org/01zvqw119","country_code":"NZ","type":"education","lineage":["https://openalex.org/I39854758"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Maryam Doborjeh","raw_affiliation_strings":["Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand"],"affiliations":[{"raw_affiliation_string":"Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand","institution_ids":["https://openalex.org/I39854758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054040512","display_name":"Wilson Wen Bin Goh","orcid":"https://orcid.org/0000-0003-3863-7501"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Wilson Wen Bin Goh","raw_affiliation_strings":["Nanyang Technological University,School of Biological Sciences,Singapore"],"affiliations":[{"raw_affiliation_string":"Nanyang Technological University,School of Biological Sciences,Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024893012","display_name":"Nikola Kasabov","orcid":"https://orcid.org/0000-0003-4433-7521"},"institutions":[{"id":"https://openalex.org/I39854758","display_name":"Auckland University of Technology","ror":"https://ror.org/01zvqw119","country_code":"NZ","type":"education","lineage":["https://openalex.org/I39854758"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Nikola Kasabov","raw_affiliation_strings":["Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand"],"affiliations":[{"raw_affiliation_string":"Auckland University of Technology,Knowledge Engineering and Discovery Research Institute, School of Engineering, Computer, and Mathematical Sciences,Auckland,New Zealand","institution_ids":["https://openalex.org/I39854758"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5090783596"],"corresponding_institution_ids":["https://openalex.org/I39854758"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33923553,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9725000262260437,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9725000262260437,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psychosis","display_name":"Psychosis","score":0.7148000001907349},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.7006999850273132},{"id":"https://openalex.org/keywords/social-cognitive-theory","display_name":"Social cognitive theory","score":0.5817000269889832},{"id":"https://openalex.org/keywords/social-cognition","display_name":"Social cognition","score":0.44589999318122864},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.44369998574256897},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.329800009727478},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"Cognitive impairment","score":0.2863999903202057}],"concepts":[{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.7148000001907349},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.7006999850273132},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6380000114440918},{"id":"https://openalex.org/C14564219","wikidata":"https://www.wikidata.org/wiki/Q383646","display_name":"Social cognitive theory","level":2,"score":0.5817000269889832},{"id":"https://openalex.org/C86658582","wikidata":"https://www.wikidata.org/wiki/Q1432778","display_name":"Social cognition","level":3,"score":0.44589999318122864},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44369998574256897},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.41589999198913574},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3772999942302704},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.329800009727478},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.3018999993801117},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.2863999903202057},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2770000100135803},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.27410000562667847},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.2689000070095062},{"id":"https://openalex.org/C201770970","wikidata":"https://www.wikidata.org/wiki/Q17143093","display_name":"Socio-cognitive","level":3,"score":0.2614000141620636},{"id":"https://openalex.org/C16634123","wikidata":"https://www.wikidata.org/wiki/Q7551393","display_name":"Social stress","level":2,"score":0.25760000944137573},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.2558000087738037},{"id":"https://openalex.org/C129564537","wikidata":"https://www.wikidata.org/wiki/Q1460873","display_name":"Neural correlates of consciousness","level":3,"score":0.2522999942302704},{"id":"https://openalex.org/C134290984","wikidata":"https://www.wikidata.org/wiki/Q5141241","display_name":"Cognitive skill","level":3,"score":0.25220000743865967},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.25220000743865967}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ijcnn64981.2025.11229023","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ijcnn64981.2025.11229023","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 International Joint Conference on Neural Networks (IJCNN)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1878915617","https://openalex.org/W1958194583","https://openalex.org/W2007636259","https://openalex.org/W2008062633","https://openalex.org/W2020237866","https://openalex.org/W2021356749","https://openalex.org/W2065105806","https://openalex.org/W2091831185","https://openalex.org/W2095064720","https://openalex.org/W2121461931","https://openalex.org/W2121637331","https://openalex.org/W2158618087","https://openalex.org/W2198642455","https://openalex.org/W2523547844","https://openalex.org/W2571700049","https://openalex.org/W2888850715","https://openalex.org/W2942320538","https://openalex.org/W2969117976","https://openalex.org/W3113965116","https://openalex.org/W3149199574","https://openalex.org/W3175847771","https://openalex.org/W3203887159","https://openalex.org/W4293425942","https://openalex.org/W4313893267","https://openalex.org/W4320912995","https://openalex.org/W4382355800","https://openalex.org/W4387496572","https://openalex.org/W4399383503","https://openalex.org/W4409125135"],"related_works":[],"abstract_inverted_index":{"The":[0],"identification":[1],"of":[2,42],"reliable":[3],"biomarkers":[4],"predicting":[5,29],"outcomes":[6],"in":[7,16,24],"ultra-high":[8],"risk":[9],"(UHR)":[10],"psychosis":[11,25,127],"remains":[12],"a":[13,91],"vital":[14],"challenge":[15],"preventive":[17],"psychiatry.":[18],"While":[19],"genetic":[20,106],"factors":[21],"are":[22],"implicated":[23],"risk,":[26],"specific":[27],"markers":[28],"social":[30,72,79,111],"and":[31,44,68,73,80,85,102,112],"cognitive":[32,74,81,113],"trajectories":[33],"have":[34],"remained":[35],"elusive.":[36],"In":[37],"this":[38],"24-month":[39],"longitudinal":[40],"study":[41],"UHR":[43,122],"Healthy":[45],"Control":[46],"(HC)":[47],"participants,":[48],"we":[49,116],"investigated":[50],"for":[51],"the":[52,55,121],"first":[53],"time":[54],"predictive":[56],"relationship":[57],"between":[58],"key":[59,105],"immune-related":[60],"genes,":[61,64,67],"inflammatory":[62],"response":[63,66],"stress":[65],"neurological-related":[69],"genes":[70],"with":[71],"outcomes.":[75],"Participants":[76],"underwent":[77],"comprehensive":[78],"assessments":[82],"at":[83],"baseline":[84],"three":[86],"6-month":[87],"intervals.":[88],"We":[89],"employed":[90],"brain-inspired":[92],"Spiking":[93],"Neural":[94],"Network":[95],"(SNN)":[96],"model":[97],"to":[98,103,124],"map":[99],"gene-behavior":[100],"interactions":[101],"identify":[104],"predictors":[107],"that":[108],"influence":[109],"both":[110],"functioning.":[114],"Additionally,":[115],"explore":[117],"subgroup":[118],"differences":[119],"within":[120],"population":[123],"further":[125],"understand":[126],"risk.":[128]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-11-14T00:00:00"}