{"id":"https://openalex.org/W2020469771","doi":"https://doi.org/10.1109/hicss.1994.323585","title":"Building integrated systems for data representation and analysis in molecular biology","display_name":"Building integrated systems for data representation and analysis in molecular biology","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2020469771","doi":"https://doi.org/10.1109/hicss.1994.323585","mag":"2020469771"},"language":"en","primary_location":{"id":"doi:10.1109/hicss.1994.323585","is_oa":false,"landing_page_url":"https://doi.org/10.1109/hicss.1994.323585","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Twenty-Seventh Hawaii International Conference on System Sciences HICSS-94","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5098324341","display_name":"Perriere","orcid":null},"institutions":[{"id":"https://openalex.org/I4210111186","display_name":"Zimmer Biomet (France)","ror":"https://ror.org/029j6tp05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111186","https://openalex.org/I4210115238"]},{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Perriere","raw_affiliation_strings":["Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France","institution_ids":["https://openalex.org/I4210111186","https://openalex.org/I100532134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098324342","display_name":"Chevenet","orcid":null},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210111186","display_name":"Zimmer Biomet (France)","ror":"https://ror.org/029j6tp05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111186","https://openalex.org/I4210115238"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Chevenet","raw_affiliation_strings":["Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France","institution_ids":["https://openalex.org/I4210111186","https://openalex.org/I100532134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098039655","display_name":"Dorkeld","orcid":null},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210111186","display_name":"Zimmer Biomet (France)","ror":"https://ror.org/029j6tp05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111186","https://openalex.org/I4210115238"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dorkeld","raw_affiliation_strings":["Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France","institution_ids":["https://openalex.org/I4210111186","https://openalex.org/I100532134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098039656","display_name":"Vermat","orcid":null},"institutions":[{"id":"https://openalex.org/I4210111186","display_name":"Zimmer Biomet (France)","ror":"https://ror.org/029j6tp05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111186","https://openalex.org/I4210115238"]},{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vermat","raw_affiliation_strings":["Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France","institution_ids":["https://openalex.org/I4210111186","https://openalex.org/I100532134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007734945","display_name":"Gautier","orcid":null},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210111186","display_name":"Zimmer Biomet (France)","ror":"https://ror.org/029j6tp05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210111186","https://openalex.org/I4210115238"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gautier","raw_affiliation_strings":["Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire de Biom\u00e9trie, G\u00e9n\u00e9tique et Biologie des Populations, Universit\u00e9 Claude Bernard-Lyon 1, Villeurbanne, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Lab. de Biometrie, Univ. Claude Bernard, Villeurbanne, France","institution_ids":["https://openalex.org/I4210111186","https://openalex.org/I100532134"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5098324341"],"corresponding_institution_ids":["https://openalex.org/I100532134","https://openalex.org/I4210111186"],"apc_list":null,"apc_paid":null,"fwci":0.1346,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.40706523,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":null,"first_page":"89","last_page":"97"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9781000018119812,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6046485900878906},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5834226012229919},{"id":"https://openalex.org/keywords/object","display_name":"Object (grammar)","score":0.5455996990203857},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5351031422615051},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5336697101593018},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5182080864906311},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4397999942302704},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.42714983224868774},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3662445843219757},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2581951916217804},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2200036644935608},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2076823115348816}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6046485900878906},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5834226012229919},{"id":"https://openalex.org/C2781238097","wikidata":"https://www.wikidata.org/wiki/Q175026","display_name":"Object (grammar)","level":2,"score":0.5455996990203857},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5351031422615051},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5336697101593018},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5182080864906311},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4397999942302704},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.42714983224868774},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3662445843219757},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2581951916217804},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2200036644935608},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2076823115348816},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/hicss.1994.323585","is_oa":false,"landing_page_url":"https://doi.org/10.1109/hicss.1994.323585","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Twenty-Seventh Hawaii International Conference on System Sciences HICSS-94","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1491802286","https://openalex.org/W1566565565","https://openalex.org/W1793475955","https://openalex.org/W1889528679","https://openalex.org/W1936296974","https://openalex.org/W1965331871","https://openalex.org/W1967442250","https://openalex.org/W1999648939","https://openalex.org/W2006231021","https://openalex.org/W2017026835","https://openalex.org/W2055043387","https://openalex.org/W2065120930","https://openalex.org/W2070360313","https://openalex.org/W2081931335","https://openalex.org/W2085122251","https://openalex.org/W2112037421","https://openalex.org/W2115164315","https://openalex.org/W2138840910","https://openalex.org/W2166099525","https://openalex.org/W2175600240","https://openalex.org/W2332784318","https://openalex.org/W2405468469","https://openalex.org/W2549117626","https://openalex.org/W2909810678","https://openalex.org/W3110152085","https://openalex.org/W4230005798","https://openalex.org/W4236236547","https://openalex.org/W4238401070","https://openalex.org/W4251728543","https://openalex.org/W4256643981","https://openalex.org/W6637943277"],"related_works":["https://openalex.org/W2086525401","https://openalex.org/W2062195135","https://openalex.org/W2006735166","https://openalex.org/W2079327011","https://openalex.org/W2053325634","https://openalex.org/W3178279768","https://openalex.org/W193851735","https://openalex.org/W2888097224","https://openalex.org/W2773861473","https://openalex.org/W1834370135"],"abstract_inverted_index":{"Biochemical":[0],"techniques":[1],"have":[2,37],"given":[3],"to":[4,21,41,94,109,145,170],"biology":[5,96],"experimental":[6],"tools":[7],"for":[8,50,159,180],"sequencing":[9,31,35],"genome":[10],"fragments.":[11,114],"These":[12],"fragments":[13,47,78],"were":[14],"of":[15,28,44,57,64,75,119,140],"a":[16,22,107],"short":[17],"length/spl":[18],"minus/often":[19],"corresponding":[20],"single":[23],"gene/spl":[24],"minus/until":[25],"the":[26,42,55,69,72,85,88,112,172],"development":[27],"extremely":[29],"fast":[30],"methods.":[32],"Now,":[33],"large":[34,77],"projects":[36],"been":[38],"started,":[39],"leading":[40],"availability":[43],"huge":[45],"continuous":[46],"(300":[48],"kBytes":[49],"yeast":[51],"chromosome":[52],"III).":[53],"Besides":[54],"problem":[56],"storing":[58],"and":[59,90,132,151,156],"representing":[60],"such":[61,120],"an":[62,117,175],"amount":[63],"data,":[65],"there":[66],"is":[67,79,168],"also":[68],"fact":[70],"that":[71,142],"internal":[73],"organization":[74],"these":[76],"often":[80],"completely":[81],"unknown.":[82],"Consecutively,":[83],"in":[84,106],"near":[86],"future,":[87],"data":[89],"knowledge":[91,126,177],"bases":[92],"dedicated":[93],"molecular":[95],"will":[97],"be":[98],"most":[99],"certainly":[100],"associated":[101],"with":[102,147],"sequence":[103],"analysis":[104],"systems":[105],"way":[108],"help":[110],"study":[111],"unannotated":[113],"We":[115],"present":[116],"example":[118],"association":[121],"between":[122],"two":[123,138],"biological":[124],"object-oriented":[125,176],"bases/spl":[127],"minus/ColiGene":[128],"(for":[129,134],"Escherichia":[130],"coli)":[131],"MultiMap":[133],"mammalian":[135],"genomes)/spl":[136],"minus/and":[137],"sets":[139],"methods":[141,173],"are":[143],"able":[144],"communicate":[146],"them:":[148],"Digit":[149],"(Dynamics":[150],"Interactive":[152],"Graphical":[153],"Integrated":[154,160],"Tools)":[155],"Misa":[157],"(Modules":[158],"Sequence":[161],"Analysis).":[162],"Then":[163],"we":[164],"show":[165],"how":[166],"it":[167],"possible":[169],"formalize":[171],"under":[174],"representation":[178],"model":[179],"tasks.<":[181],"<ETX":[182],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[183],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">&gt;</ETX>":[184]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}