{"id":"https://openalex.org/W3208650932","doi":"https://doi.org/10.1109/dsaa53316.2021.9564158","title":"Discovery of Patient Phenotypes through Multi-layer Network Analysis on the Example of Tinnitus","display_name":"Discovery of Patient Phenotypes through Multi-layer Network Analysis on the Example of Tinnitus","publication_year":2021,"publication_date":"2021-10-06","ids":{"openalex":"https://openalex.org/W3208650932","doi":"https://doi.org/10.1109/dsaa53316.2021.9564158","mag":"3208650932"},"language":"en","primary_location":{"id":"doi:10.1109/dsaa53316.2021.9564158","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dsaa53316.2021.9564158","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE 8th International Conference on Data Science and Advanced Analytics (DSAA)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012197573","display_name":"Clara Puga","orcid":"https://orcid.org/0000-0002-4437-2178"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Clara Puga","raw_affiliation_strings":["Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany"],"affiliations":[{"raw_affiliation_string":"Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069003426","display_name":"Uli Niemann","orcid":"https://orcid.org/0000-0001-9634-2248"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Uli Niemann","raw_affiliation_strings":["Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany"],"affiliations":[{"raw_affiliation_string":"Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031994646","display_name":"Vishnu Unnikrishnan","orcid":"https://orcid.org/0000-0002-0086-594X"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Vishnu Unnikrishnan","raw_affiliation_strings":["Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany"],"affiliations":[{"raw_affiliation_string":"Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032307445","display_name":"Miro Schleicher","orcid":"https://orcid.org/0000-0002-5987-5325"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Miro Schleicher","raw_affiliation_strings":["Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany"],"affiliations":[{"raw_affiliation_string":"Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065508660","display_name":"Winfried Schlee","orcid":"https://orcid.org/0000-0001-7942-1788"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Winfried Schlee","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, University of Regensburg, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, University of Regensburg, Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083456364","display_name":"Myra Spiliopoulou","orcid":"https://orcid.org/0000-0002-1828-5759"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Myra Spiliopoulou","raw_affiliation_strings":["Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany"],"affiliations":[{"raw_affiliation_string":"Knowledge Management & Discovery Lab, Otto-von-Guericke University Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5012197573"],"corresponding_institution_ids":["https://openalex.org/I95793202"],"apc_list":null,"apc_paid":null,"fwci":0.6025,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.59987061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.991599977016449,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.9671000242233276,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tinnitus","display_name":"Tinnitus","score":0.7028062343597412},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.6406327486038208},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.6127313375473022},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.518286406993866},{"id":"https://openalex.org/keywords/layer","display_name":"Layer (electronics)","score":0.47287553548812866},{"id":"https://openalex.org/keywords/community-structure","display_name":"Community structure","score":0.4450148344039917},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4208531677722931},{"id":"https://openalex.org/keywords/baseline","display_name":"Baseline (sea)","score":0.4148622751235962},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.38896703720092773},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2956202030181885},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.20954596996307373},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.18910381197929382},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.13132622838020325},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1278703510761261}],"concepts":[{"id":"https://openalex.org/C2776992516","wikidata":"https://www.wikidata.org/wiki/Q192309","display_name":"Tinnitus","level":2,"score":0.7028062343597412},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6406327486038208},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.6127313375473022},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.518286406993866},{"id":"https://openalex.org/C2779227376","wikidata":"https://www.wikidata.org/wiki/Q6505497","display_name":"Layer (electronics)","level":2,"score":0.47287553548812866},{"id":"https://openalex.org/C133079900","wikidata":"https://www.wikidata.org/wiki/Q5155065","display_name":"Community structure","level":2,"score":0.4450148344039917},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4208531677722931},{"id":"https://openalex.org/C12725497","wikidata":"https://www.wikidata.org/wiki/Q810247","display_name":"Baseline (sea)","level":2,"score":0.4148622751235962},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38896703720092773},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2956202030181885},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.20954596996307373},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.18910381197929382},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13132622838020325},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1278703510761261},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/dsaa53316.2021.9564158","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dsaa53316.2021.9564158","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE 8th International Conference on Data Science and Advanced Analytics (DSAA)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1812137573","https://openalex.org/W1966119405","https://openalex.org/W1966688265","https://openalex.org/W1998903052","https://openalex.org/W2001993563","https://openalex.org/W2005464046","https://openalex.org/W2074617510","https://openalex.org/W2080805836","https://openalex.org/W2097278341","https://openalex.org/W2123848671","https://openalex.org/W2588720584","https://openalex.org/W2782612985","https://openalex.org/W2796646122","https://openalex.org/W2897249806","https://openalex.org/W2940923825","https://openalex.org/W2982546097","https://openalex.org/W2996569343","https://openalex.org/W3022273794","https://openalex.org/W3023628437","https://openalex.org/W3036863310","https://openalex.org/W3080318198","https://openalex.org/W3093301018","https://openalex.org/W3102578849","https://openalex.org/W3104058381","https://openalex.org/W3106188259","https://openalex.org/W3106488715","https://openalex.org/W3106982303","https://openalex.org/W3128119142","https://openalex.org/W3214803442","https://openalex.org/W6777375974"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2348097614","https://openalex.org/W2406205719","https://openalex.org/W2369609740","https://openalex.org/W2101452068","https://openalex.org/W2998883339","https://openalex.org/W3009387340","https://openalex.org/W3175441611","https://openalex.org/W2095842474"],"abstract_inverted_index":{"Electronic":[0],"health":[1],"records":[2],"(EHR)":[3],"often":[4],"include":[5],"multiple":[6],"perspectives":[7,30,60],"on":[8,114],"a":[9,56,66,79,124,137],"patient's":[10],"current":[11],"state":[12],"of":[13,34,65,72,84,96,111,119],"well-being":[14],"(e.g.":[15],"vital":[16],"signs":[17],"and":[18,38],"subjective":[19],"indicators":[20],"measured":[21],"by":[22],"questionnaires).":[23],"In":[24,146],"this":[25,149],"study,":[26],"we":[27,50,77,107,135],"use":[28],"these":[29,41,85],"to":[31,47,102,126,141,160],"build":[32],"phenotypes":[33,42,71,91],"chronic":[35],"tinnitus":[36],"patients":[37,52,73,97],"investigate":[39],"how":[40],"are":[43,61,99],"associated":[44],"with":[45],"response":[46],"treatment.":[48],"Therefore,":[49],"model":[51],"as":[53,63,90],"nodes":[54],"in":[55,74],"network,":[57,76],"where":[58,155],"those":[59],"interpreted":[62],"layers":[64,113,128],"multi-layer":[67],"network.":[68],"To":[69],"identify":[70],"the":[75,103,109,112,115,143,152,156],"implement":[78],"community":[80,117,131],"detection":[81],"algorithm.":[82],"Some":[83],"communities":[86],"can":[87],"be":[88],"considered":[89],"if":[92],"they":[93],"represent":[94],"subgroups":[95],"that":[98],"similar":[100],"according":[101],"investigated":[104],"perspectives.":[105],"Furthermore,":[106],"analyze":[108],"influence":[110],"final":[116],"structure":[118,132],"patients.":[120,162],"We":[121],"then":[122],"propose":[123],"method":[125],"add":[127],"given":[129],"their":[130],"similarity.":[133],"Finally,":[134],"fit":[136],"model,":[138],"per":[139],"community,":[140],"predict":[142],"treatment":[144],"outcome.":[145],"some":[147],"communities,":[148],"prediction":[150],"outperformed":[151],"baseline":[153],"scenario":[154],"predictor":[157],"was":[158],"fitted":[159],"all":[161]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}