{"id":"https://openalex.org/W4412021343","doi":"https://doi.org/10.1109/cbms65348.2025.00127","title":"Classifying Residual Inhibition in the Context of Tinnitus: An Interpretable Machine Learning Approach","display_name":"Classifying Residual Inhibition in the Context of Tinnitus: An Interpretable Machine Learning Approach","publication_year":2025,"publication_date":"2025-06-18","ids":{"openalex":"https://openalex.org/W4412021343","doi":"https://doi.org/10.1109/cbms65348.2025.00127"},"language":"en","primary_location":{"id":"doi:10.1109/cbms65348.2025.00127","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms65348.2025.00127","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE 38th International Symposium on Computer-Based Medical Systems (CBMS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104226442","display_name":"Hafez Kader","orcid":null},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Hafez Kader","raw_affiliation_strings":["Otto von Guericke University,Autonomous Multisensor Systems Group, Institute for Intelligent Cooperating Systems,Magdeburg,Germany"],"affiliations":[{"raw_affiliation_string":"Otto von Guericke University,Autonomous Multisensor Systems Group, Institute for Intelligent Cooperating Systems,Magdeburg,Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106890908","display_name":"Steven C. Marcrum","orcid":"https://orcid.org/0000-0001-7639-5318"},"institutions":[{"id":"https://openalex.org/I3129555431","display_name":"University Hospital Regensburg","ror":"https://ror.org/01226dv09","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3129555431"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steven C. Marcrum","raw_affiliation_strings":["University Hospital Regensburg,Department of Otolaryngology,Regensburg,Germany"],"affiliations":[{"raw_affiliation_string":"University Hospital Regensburg,Department of Otolaryngology,Regensburg,Germany","institution_ids":["https://openalex.org/I3129555431"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016972713","display_name":"Milena Engelke","orcid":"https://orcid.org/0000-0002-7346-0441"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Milena Engelke","raw_affiliation_strings":["University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany"],"affiliations":[{"raw_affiliation_string":"University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025182701","display_name":"Niklas K. Edvall","orcid":"https://orcid.org/0000-0002-6427-1198"},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Niklas K. Edvall","raw_affiliation_strings":["Karolinska Institutet,Laboratory of Translational Auditory Neuroscience,Department of Physiology and Pharmacology,Stockholm,Sweden"],"affiliations":[{"raw_affiliation_string":"Karolinska Institutet,Laboratory of Translational Auditory Neuroscience,Department of Physiology and Pharmacology,Stockholm,Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064104774","display_name":"Berthold Langguth","orcid":"https://orcid.org/0000-0002-7066-510X"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Berthold Langguth","raw_affiliation_strings":["University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany"],"affiliations":[{"raw_affiliation_string":"University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043433931","display_name":"Birgit Mazurek","orcid":"https://orcid.org/0000-0002-9587-6632"},"institutions":[{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Birgit Mazurek","raw_affiliation_strings":["Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Hurnboldt-Universität zu Berlin, and Berlin Institute of Health,T'innitus Center"],"affiliations":[{"raw_affiliation_string":"Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Hurnboldt-Universität zu Berlin, and Berlin Institute of Health,T'innitus Center","institution_ids":["https://openalex.org/I4210139777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006047589","display_name":"Jos\u00e9 A. L\u00f3pez\u2010Esc\u00e1mez","orcid":"https://orcid.org/0000-0002-8583-1430"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jose Antonio Lopez-Escamez","raw_affiliation_strings":["School of Medical Sciences, The Kolling Institute, University of Sydney,Meniere Disease Neuroscience Research Program, Faculty of Medicine & Health,Sydney,NSW,Australia,2065"],"affiliations":[{"raw_affiliation_string":"School of Medical Sciences, The Kolling Institute, University of Sydney,Meniere Disease Neuroscience Research Program, Faculty of Medicine & Health,Sydney,NSW,Australia,2065","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001128222","display_name":"Dimitrios Kikidis","orcid":"https://orcid.org/0000-0002-1445-5474"},"institutions":[{"id":"https://openalex.org/I4210165841","display_name":"Hippocration General Hospital","ror":"https://ror.org/05v5wwy67","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210165841"]},{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitrios Kikidis","raw_affiliation_strings":["National and Kapodistrian University of Athens,Hippocrateion General Hospital,First Department of Otorhinolaryngology, Head and Neck Surgery,Athens,Greece"],"affiliations":[{"raw_affiliation_string":"National and Kapodistrian University of Athens,Hippocrateion General Hospital,First Department of Otorhinolaryngology, Head and Neck Surgery,Athens,Greece","institution_ids":["https://openalex.org/I4210165841","https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052794208","display_name":"Rilana Cima","orcid":"https://orcid.org/0000-0001-8465-3313"},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Rilana Cima","raw_affiliation_strings":["Katholieke Universiteit Leuven,Department of Health Psychology,Leuven,Belgium"],"affiliations":[{"raw_affiliation_string":"Katholieke Universiteit Leuven,Department of Health Psychology,Leuven,Belgium","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055037608","display_name":"Patrick Neff","orcid":"https://orcid.org/0000-0003-3174-4910"},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I4210100468","display_name":"University Hospital of Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"funder","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Patrick Neff","raw_affiliation_strings":["University of Zurich,University Hospital Zurich,Department of Otorhinolaryngology, Head and Neck Surgery,Switzerland"],"affiliations":[{"raw_affiliation_string":"University of Zurich,University Hospital Zurich,Department of Otorhinolaryngology, Head and Neck Surgery,Switzerland","institution_ids":["https://openalex.org/I4210100468","https://openalex.org/I202697423"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065508660","display_name":"Winfried Schlee","orcid":"https://orcid.org/0000-0001-7942-1788"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Winfried Schlee","raw_affiliation_strings":["University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany"],"affiliations":[{"raw_affiliation_string":"University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany","institution_ids":["https://openalex.org/I60668342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048911928","display_name":"Christopher R. Cederroth","orcid":"https://orcid.org/0000-0001-7267-5136"},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christopher R. Cederroth","raw_affiliation_strings":["Karolinska Institutet,Laboratory of Translational Auditory Neuroscience,Department of Physiology and Pharmacology,Stockholm,Sweden"],"affiliations":[{"raw_affiliation_string":"Karolinska Institutet,Laboratory of Translational Auditory Neuroscience,Department of Physiology and Pharmacology,Stockholm,Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080767310","display_name":"Benjamin Noack","orcid":"https://orcid.org/0000-0001-8996-5738"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Benjamin Noack","raw_affiliation_strings":["Otto von Guericke University,Autonomous Multisensor Systems Group, Institute for Intelligent Cooperating Systems,Magdeburg,Germany"],"affiliations":[{"raw_affiliation_string":"Otto von Guericke University,Autonomous Multisensor Systems Group, Institute for Intelligent Cooperating Systems,Magdeburg,Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083456364","display_name":"Myra Spiliopoulou","orcid":"https://orcid.org/0000-0002-1828-5759"},"institutions":[{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke University Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Myra Spiliopoulou","raw_affiliation_strings":["Otto von Guericke University,Knowledge Management and Discovery Lab, Faculty of Computer Science,Magdeburg,Germany"],"affiliations":[{"raw_affiliation_string":"Otto von Guericke University,Knowledge Management and Discovery Lab, Faculty of Computer Science,Magdeburg,Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086132743","display_name":"Stefan Schoisswohl","orcid":"https://orcid.org/0000-0003-3633-999X"},"institutions":[{"id":"https://openalex.org/I60668342","display_name":"University of Regensburg","ror":"https://ror.org/01eezs655","country_code":"DE","type":"education","lineage":["https://openalex.org/I60668342"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Schoisswohl","raw_affiliation_strings":["University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany"],"affiliations":[{"raw_affiliation_string":"University of Regensburg,Department of Psychiatry and Psychotherapy,Regensburg,Germany","institution_ids":["https://openalex.org/I60668342"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5104226442"],"corresponding_institution_ids":["https://openalex.org/I95793202"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.30513051,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"605","last_page":"611"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13869","display_name":"Ocular and Laser Science Research","score":0.2833000123500824,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13869","display_name":"Ocular and Laser Science Research","score":0.2833000123500824,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.24480000138282776,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/residual","display_name":"Residual","score":0.7654238939285278},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.692333459854126},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6791815757751465},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6395628452301025},{"id":"https://openalex.org/keywords/tinnitus","display_name":"Tinnitus","score":0.6005121469497681},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.536260724067688},{"id":"https://openalex.org/keywords/speech-recognition","display_name":"Speech recognition","score":0.345135897397995},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.10872673988342285},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.08830788731575012},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.07804423570632935},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.05251741409301758}],"concepts":[{"id":"https://openalex.org/C155512373","wikidata":"https://www.wikidata.org/wiki/Q287450","display_name":"Residual","level":2,"score":0.7654238939285278},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.692333459854126},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6791815757751465},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6395628452301025},{"id":"https://openalex.org/C2776992516","wikidata":"https://www.wikidata.org/wiki/Q192309","display_name":"Tinnitus","level":2,"score":0.6005121469497681},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.536260724067688},{"id":"https://openalex.org/C28490314","wikidata":"https://www.wikidata.org/wiki/Q189436","display_name":"Speech recognition","level":1,"score":0.345135897397995},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10872673988342285},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.08830788731575012},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.07804423570632935},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.05251741409301758},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cbms65348.2025.00127","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms65348.2025.00127","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE 38th International Symposium on Computer-Based Medical Systems (CBMS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1678356000","https://openalex.org/W1967349799","https://openalex.org/W2001993563","https://openalex.org/W2036036397","https://openalex.org/W2081729067","https://openalex.org/W2102636708","https://openalex.org/W2610332124","https://openalex.org/W2767804392","https://openalex.org/W2784068557","https://openalex.org/W2913240367","https://openalex.org/W2920577134","https://openalex.org/W2920860670","https://openalex.org/W2921710160","https://openalex.org/W2966218717","https://openalex.org/W2998981883","https://openalex.org/W3082386257","https://openalex.org/W3118773135","https://openalex.org/W3127429504","https://openalex.org/W3128119142","https://openalex.org/W3134944473","https://openalex.org/W3139385056","https://openalex.org/W3147472256","https://openalex.org/W3158928250","https://openalex.org/W3159396962","https://openalex.org/W3161904859","https://openalex.org/W4207044611","https://openalex.org/W4226072015","https://openalex.org/W4234570562","https://openalex.org/W4283736413","https://openalex.org/W4290659914","https://openalex.org/W4315700488","https://openalex.org/W4397042613","https://openalex.org/W4400275440","https://openalex.org/W4400762160","https://openalex.org/W4403209408","https://openalex.org/W6838220477"],"related_works":["https://openalex.org/W2333533852","https://openalex.org/W2297779309","https://openalex.org/W2139696050","https://openalex.org/W2239705608","https://openalex.org/W2762112353","https://openalex.org/W624181032","https://openalex.org/W2965355650","https://openalex.org/W3014341250","https://openalex.org/W2399625182","https://openalex.org/W29859598"],"abstract_inverted_index":{"Residual":[0],"inhibition":[1],"(RI)":[2],"is":[3,158],"a":[4,17,22,61,88,97,130,164],"phenomenon":[5],"observed":[6],"in":[7,36,112],"many":[8],"tinnitus":[9,12],"patients,":[10],"where":[11],"remains":[13],"temporarily":[14],"suppressed":[15],"for":[16,83,138,167],"short":[18],"duration\u2014typically":[19],"less":[20],"than":[21],"minute-after":[23],"the":[24,51,67,71,104,120],"cessation":[25],"of":[26,33,53,70,106,123],"an":[27],"appropriate":[28],"masking":[29],"stimulus.":[30],"Despite":[31],"decades":[32],"clinical":[34,108],"interest":[35],"RI,":[37],"machine":[38],"learning":[39,132],"(ML)-based,":[40],"feature-driven":[41],"classification":[42],"approaches":[43],"remain":[44],"scarce.":[45],"In":[46],"this":[47],"study,":[48],"we":[49,118],"investigate":[50],"potential":[52],"ML":[54],"models":[55],"to":[56,86,134,161],"classify":[57],"RI":[58,101,124,147,156],"by":[59],"developing":[60],"dedicated":[62],"data":[63,85],"analysis":[64],"pipeline.":[65],"Given":[66],"heterogeneous":[68],"nature":[69],"features\u2014including":[72],"numerical,":[73],"binary,":[74],"and":[75,91,109],"ordinal":[76],"variables-we":[77],"apply":[78],"feature":[79],"importance":[80],"techniques":[81],"tailored":[82],"mixed-type":[84],"ensure":[87],"comprehensive":[89],"evaluation":[90],"improve":[92],"interpretability.":[93],"Our":[94],"results":[95],"demonstrate":[96],"clear":[98],"separation":[99],"between":[100],"classes,":[102],"highlighting":[103],"relevance":[105,137],"specific":[107],"audiological":[110],"factors":[111],"distinguishing":[113],"them.":[114],"Building":[115],"on":[116],"this,":[117],"assess":[119],"predictive":[121],"power":[122],"classifications":[125],"with":[126],"high":[127],"confidence":[128],"within":[129],"supervised":[131],"framework":[133],"determine":[135],"their":[136],"treatment":[139,168],"outcome":[140],"prediction.":[141],"While":[142],"our":[143],"findings":[144],"confirm":[145],"that":[146,155],"can":[148],"be":[149],"effectively":[150],"classified,":[151],"they":[152],"also":[153],"suggest":[154],"alone":[157],"not":[159],"sufficient":[160],"serve":[162],"as":[163],"reliable":[165],"predictor":[166],"outcomes.":[169]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}