{"id":"https://openalex.org/W1969241653","doi":"https://doi.org/10.1109/cbms.2012.6266344","title":"Automated segmentation of optic disc and optic cup in fundus images for glaucoma diagnosis","display_name":"Automated segmentation of optic disc and optic cup in fundus images for glaucoma diagnosis","publication_year":2012,"publication_date":"2012-06-01","ids":{"openalex":"https://openalex.org/W1969241653","doi":"https://doi.org/10.1109/cbms.2012.6266344","mag":"1969241653"},"language":"en","primary_location":{"id":"doi:10.1109/cbms.2012.6266344","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms.2012.6266344","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111473819","display_name":"Fengshou Yin","orcid":null},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Fengshou Yin","raw_affiliation_strings":["Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","Institute for Infocomm Research, A-star, Singapore"],"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","institution_ids":["https://openalex.org/I3005327000","https://openalex.org/I115228651"]},{"raw_affiliation_string":"Institute for Infocomm Research, A-star, Singapore","institution_ids":["https://openalex.org/I3005327000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100325209","display_name":"Jiang Liu","orcid":"https://orcid.org/0000-0001-6281-6505"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jiang Liu","raw_affiliation_strings":["Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","Institute for Infocomm Research, A-star, Singapore"],"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","institution_ids":["https://openalex.org/I3005327000","https://openalex.org/I115228651"]},{"raw_affiliation_string":"Institute for Infocomm Research, A-star, Singapore","institution_ids":["https://openalex.org/I3005327000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015497605","display_name":"Damon Wing Kee Wong","orcid":"https://orcid.org/0000-0003-4601-9121"},"institutions":[{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]},{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Damon Wing Kee Wong","raw_affiliation_strings":["Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","Institute for Infocomm Research, A-star, Singapore"],"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","institution_ids":["https://openalex.org/I3005327000","https://openalex.org/I115228651"]},{"raw_affiliation_string":"Institute for Infocomm Research, A-star, Singapore","institution_ids":["https://openalex.org/I3005327000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102095402","display_name":"Ngan Meng Tan","orcid":null},"institutions":[{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]},{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Ngan Meng Tan","raw_affiliation_strings":["Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","Institute for Infocomm Research, A-star, Singapore"],"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Agency for Science, Technology and Research, Singapore","institution_ids":["https://openalex.org/I3005327000","https://openalex.org/I115228651"]},{"raw_affiliation_string":"Institute for Infocomm Research, A-star, Singapore","institution_ids":["https://openalex.org/I3005327000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084913828","display_name":"Carol Y. Cheung","orcid":"https://orcid.org/0000-0003-0869-859X"},"institutions":[{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Carol Cheung","raw_affiliation_strings":["Singapore Eye Research Institute, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Eye Research Institute, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057053486","display_name":"Mani Baskaran","orcid":"https://orcid.org/0000-0002-4639-7387"},"institutions":[{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Mani Baskaran","raw_affiliation_strings":["Singapore Eye Research Institute, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Eye Research Institute, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022464374","display_name":"Tin Aung","orcid":"https://orcid.org/0000-0002-7916-0589"},"institutions":[{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Tin Aung","raw_affiliation_strings":["Singapore Eye Research Institute, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Eye Research Institute, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072258594","display_name":"Tien Yin Wong","orcid":"https://orcid.org/0000-0002-8448-1264"},"institutions":[{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Tien Yin Wong","raw_affiliation_strings":["Singapore Eye Research Institute, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Eye Research Institute, Singapore","institution_ids":["https://openalex.org/I4210116917"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5111473819"],"corresponding_institution_ids":["https://openalex.org/I115228651","https://openalex.org/I3005327000"],"apc_list":null,"apc_paid":null,"fwci":5.7646,"has_fulltext":false,"cited_by_count":116,"citation_normalized_percentile":{"value":0.96016413,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12549","display_name":"Image and Object Detection Techniques","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optic-disc","display_name":"Optic disc","score":0.8881624937057495},{"id":"https://openalex.org/keywords/optic-cup","display_name":"Optic cup (embryology)","score":0.84159255027771},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7636416554450989},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7288306951522827},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6833587884902954},{"id":"https://openalex.org/keywords/glaucoma","display_name":"Glaucoma","score":0.668479859828949},{"id":"https://openalex.org/keywords/fundus","display_name":"Fundus (uterus)","score":0.6669521927833557},{"id":"https://openalex.org/keywords/hough-transform","display_name":"Hough transform","score":0.6221073865890503},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5832513570785522},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.48470306396484375},{"id":"https://openalex.org/keywords/s\u00f8rensen\u2013dice-coefficient","display_name":"S\u00f8rensen\u2013Dice coefficient","score":0.433817982673645},{"id":"https://openalex.org/keywords/optic-disk","display_name":"Optic disk","score":0.4293137192726135},{"id":"https://openalex.org/keywords/cad","display_name":"CAD","score":0.4191305637359619},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3280487060546875},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.1674969494342804},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.14393967390060425},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.08460325002670288},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08415302634239197},{"id":"https://openalex.org/keywords/engineering-drawing","display_name":"Engineering drawing","score":0.0659227967262268}],"concepts":[{"id":"https://openalex.org/C2779735895","wikidata":"https://www.wikidata.org/wiki/Q16873995","display_name":"Optic disc","level":3,"score":0.8881624937057495},{"id":"https://openalex.org/C96021297","wikidata":"https://www.wikidata.org/wiki/Q7098791","display_name":"Optic cup (embryology)","level":5,"score":0.84159255027771},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7636416554450989},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7288306951522827},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6833587884902954},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.668479859828949},{"id":"https://openalex.org/C2776391266","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Fundus (uterus)","level":2,"score":0.6669521927833557},{"id":"https://openalex.org/C200518788","wikidata":"https://www.wikidata.org/wiki/Q195076","display_name":"Hough transform","level":3,"score":0.6221073865890503},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5832513570785522},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.48470306396484375},{"id":"https://openalex.org/C163892561","wikidata":"https://www.wikidata.org/wiki/Q2613728","display_name":"S\u00f8rensen\u2013Dice coefficient","level":4,"score":0.433817982673645},{"id":"https://openalex.org/C2983497740","wikidata":"https://www.wikidata.org/wiki/Q16873995","display_name":"Optic disk","level":3,"score":0.4293137192726135},{"id":"https://openalex.org/C194789388","wikidata":"https://www.wikidata.org/wiki/Q17855283","display_name":"CAD","level":2,"score":0.4191305637359619},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3280487060546875},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.1674969494342804},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.14393967390060425},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08460325002670288},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08415302634239197},{"id":"https://openalex.org/C199639397","wikidata":"https://www.wikidata.org/wiki/Q1788588","display_name":"Engineering drawing","level":1,"score":0.0659227967262268},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0},{"id":"https://openalex.org/C114696181","wikidata":"https://www.wikidata.org/wiki/Q5422650","display_name":"Eye development","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cbms.2012.6266344","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms.2012.6266344","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1868104444","https://openalex.org/W1896969699","https://openalex.org/W1970015880","https://openalex.org/W1974969377","https://openalex.org/W1998106502","https://openalex.org/W2014559426","https://openalex.org/W2025049031","https://openalex.org/W2038375429","https://openalex.org/W2038952578","https://openalex.org/W2056871061","https://openalex.org/W2057266151","https://openalex.org/W2104324599","https://openalex.org/W2141575807","https://openalex.org/W2145023731","https://openalex.org/W2159395868","https://openalex.org/W2170203892","https://openalex.org/W6642818901","https://openalex.org/W6660273779"],"related_works":["https://openalex.org/W2890764477","https://openalex.org/W2779576471","https://openalex.org/W3131680944","https://openalex.org/W300732441","https://openalex.org/W2081178133","https://openalex.org/W2531866780","https://openalex.org/W2513292194","https://openalex.org/W3180652865","https://openalex.org/W2798412772","https://openalex.org/W1586266070"],"abstract_inverted_index":{"The":[0,55,88,98,119,134],"vertical":[1],"Cup-to-Disc":[2],"Ratio":[3],"(CDR)":[4],"is":[5,24,83,108],"an":[6],"important":[7],"indicator":[8],"in":[9,150],"the":[10,17,41,44,71,76,103],"diagnosis":[11,30],"of":[12,16,43,70,95,128],"glaucoma.":[13],"Automatic":[14],"segmentation":[15,42,69,107],"optic":[18,22,45,48,79],"disc":[19,46,104],"(OD)":[20],"and":[21,47,62,105,110,138],"cup":[23,49,80,106],"crucial":[25],"towards":[26],"a":[27,36,63,84,93,123,141,151],"good":[28,142],"computer-aided":[29],"(CAD)":[31],"system.":[32,155],"This":[33],"paper":[34],"presents":[35],"statistical":[37],"model-based":[38],"method":[39,56,77,121,146],"for":[40,68,102,144],"from":[50],"digital":[51],"color":[52],"fundus":[53],"images.":[54,97],"combines":[57],"knowledge-based":[58],"Circular":[59],"Hough":[60],"Transform":[61],"novel":[64],"optimal":[65],"channel":[66],"selection":[67],"OD.":[72],"Moreover,":[73],"we":[74],"extended":[75],"to":[78,147],"segmentation,":[81],"which":[82,113,130],"more":[85],"challenging":[86],"task.":[87],"system":[89],"was":[90],"tested":[91],"on":[92],"dataset":[94],"325":[96],"average":[99],"Dice":[100],"coefficient":[101],"0.92":[109],"0.81":[111],"respectively,":[112],"improves":[114],"significantly":[115],"over":[116],"existing":[117,132],"methods.":[118,133],"proposed":[120],"has":[122],"mean":[124],"absolute":[125],"CDR":[126],"error":[127],"0.10,":[129],"outperforms":[131],"results":[135],"are":[136],"promising":[137],"thus":[139],"demonstrate":[140],"potential":[143],"this":[145],"be":[148],"used":[149],"mass":[152],"screening":[153],"CAD":[154]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":21},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":8}],"updated_date":"2026-04-02T15:55:50.835912","created_date":"2025-10-10T00:00:00"}