{"id":"https://openalex.org/W2074473478","doi":"https://doi.org/10.1109/bmei.2012.6512951","title":"Analysis of synonymous codon usage on the small subunit of ribonucleotide reductase gene from duck plague virus","display_name":"Analysis of synonymous codon usage on the small subunit of ribonucleotide reductase gene from duck plague virus","publication_year":2012,"publication_date":"2012-10-01","ids":{"openalex":"https://openalex.org/W2074473478","doi":"https://doi.org/10.1109/bmei.2012.6512951","mag":"2074473478"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2012.6512951","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2012.6512951","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 5th International Conference on BioMedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100756725","display_name":"Min Wei","orcid":"https://orcid.org/0000-0002-2649-9271"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Min Wei","raw_affiliation_strings":["Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China"],"affiliations":[{"raw_affiliation_string":"Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045418032","display_name":"Anchun Cheng","orcid":"https://orcid.org/0000-0001-6093-353X"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anchun Cheng","raw_affiliation_strings":["Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China"],"affiliations":[{"raw_affiliation_string":"Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102002022","display_name":"Mingshu Wang","orcid":"https://orcid.org/0000-0001-9652-392X"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingshu Wang","raw_affiliation_strings":["Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China"],"affiliations":[{"raw_affiliation_string":"Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031988329","display_name":"Jie Huang","orcid":"https://orcid.org/0000-0002-9036-4304"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Huang","raw_affiliation_strings":["Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China"],"affiliations":[{"raw_affiliation_string":"Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105988307","display_name":"Xiaoyue Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyue Chen","raw_affiliation_strings":["Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China"],"affiliations":[{"raw_affiliation_string":"Institute of Preventive Veterinary Medicine, Sichuan, Agricultural University, Wenjiang, Chengdu city, Sichuan, 611130, P.R. China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Inst. of Preventive Veterinary Med., Agric. Univ., Chengdu, China","institution_ids":["https://openalex.org/I37574244"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100756725"],"corresponding_institution_ids":["https://openalex.org/I37574244"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09682588,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":null,"first_page":"1159","last_page":"1164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.8066324591636658},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.7066793441772461},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.6832727193832397},{"id":"https://openalex.org/keywords/codon-usage-bias","display_name":"Codon usage bias","score":0.6522424817085266},{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.6456524729728699},{"id":"https://openalex.org/keywords/ribonucleotide-reductase","display_name":"Ribonucleotide reductase","score":0.46726149320602417},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.4380512237548828},{"id":"https://openalex.org/keywords/protein-subunit","display_name":"Protein subunit","score":0.22592005133628845},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.2030605971813202}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8066324591636658},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7066793441772461},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6832727193832397},{"id":"https://openalex.org/C87253356","wikidata":"https://www.wikidata.org/wiki/Q1106472","display_name":"Codon usage bias","level":4,"score":0.6522424817085266},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.6456524729728699},{"id":"https://openalex.org/C4710235","wikidata":"https://www.wikidata.org/wiki/Q420089","display_name":"Ribonucleotide reductase","level":4,"score":0.46726149320602417},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4380512237548828},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.22592005133628845},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2030605971813202}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2012.6512951","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2012.6512951","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 5th International Conference on BioMedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6600000262260437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1964939210","https://openalex.org/W1978033184","https://openalex.org/W1978097322","https://openalex.org/W1989529069","https://openalex.org/W1991049350","https://openalex.org/W1998643471","https://openalex.org/W2004027140","https://openalex.org/W2004146038","https://openalex.org/W2018590530","https://openalex.org/W2029539611","https://openalex.org/W2043334546","https://openalex.org/W2050145486","https://openalex.org/W2052149930","https://openalex.org/W2071012814","https://openalex.org/W2077319392","https://openalex.org/W2085052161","https://openalex.org/W2100364553","https://openalex.org/W2104217739","https://openalex.org/W2104593237","https://openalex.org/W2122343942","https://openalex.org/W2127064445","https://openalex.org/W2135240797","https://openalex.org/W2138627718","https://openalex.org/W2140261743","https://openalex.org/W2148734328","https://openalex.org/W2151314777","https://openalex.org/W2153810796","https://openalex.org/W2163703477","https://openalex.org/W2167126318","https://openalex.org/W4241033572","https://openalex.org/W4256321774","https://openalex.org/W6675469575"],"related_works":["https://openalex.org/W2112877681","https://openalex.org/W1540828223","https://openalex.org/W1985154969","https://openalex.org/W2038408318","https://openalex.org/W1564559265","https://openalex.org/W2015096425","https://openalex.org/W1966015348","https://openalex.org/W2102511336","https://openalex.org/W2921764584","https://openalex.org/W1866610019"],"abstract_inverted_index":{"Duck":[0],"plague":[1],"virus":[2,7],"(DPV)":[3],"is":[4],"a":[5,61,69,191,198],"widespread":[6],"in":[8,101,141],"all":[9],"members":[10],"of":[11,15,40,47,64,76,81,110,117,159,163,174,193],"the":[12,16,25,31,45,53,73,84,102,107,118,125,150,153,157,164,171,183,194,202,205],"family":[13,26],"Anatidae":[14],"order":[17],"Anseriformes,":[18],"and":[19,44,68,83,121,144,152,196,204],"it":[20],"has":[21],"been":[22],"classified":[23],"into":[24],"Herpesviridae.":[27],"In":[28,155],"this":[29],"study,":[30],"relative":[32],"synonymous":[33],"codon":[34,65,126],"usage":[35,66,127],"(RSCU)":[36],"values,":[37,43,120],"effective":[38],"number":[39],"codons":[41,92,105],"(ENC)":[42],"frequencies":[46],"nucleotide":[48],"G":[49],"+":[50],"C":[51],"at":[52],"third":[54],"position":[55],"(GC3s)":[56],"contents":[57,123],"were":[58,88,97,129],"investigated,":[59],"meanwhile,":[60],"comparative":[62,115],"analysis":[63,71,116,185],"patterns":[67,128],"phylogenetic":[70,184],"for":[72,93],"small":[74],"subunit":[75],"ribonucleotide":[77],"reductase":[78],"(R2)":[79],"gene":[80,176],"DPV":[82,111,146,188],"other":[85],"25":[86],"herpesviruses":[87],"performed.":[89],"The":[90,114],"optimal":[91],"each":[94],"amino":[95],"acid":[96],"A-ended":[98],"or":[99],"T-ended":[100],"59":[103],"sense":[104],"from":[106,179],"RSCU":[108],"values":[109],"R2":[112,137,167,175],"gene.":[113],"ENC":[119,160],"GC3s":[122,162],"showed":[124],"not":[130],"phylogenetically":[131],"conserved":[132],"among":[133],"these":[134],"26":[135,165],"herpesvirus":[136,166],"genes,":[138],"but":[139],"similarity":[140],"different":[142],"genera,":[143],"that":[145,170,187],"was":[147],"close":[148,199],"to":[149],"mardivirus":[151,203],"iltovirus.":[154],"addition,":[156],"plot":[158],"vs.":[161],"genes":[168],"indicated":[169],"genetic":[172],"characteristics":[173],"possibly":[177],"resulted":[178],"mutation":[180],"pressure.":[181],"Furthermore,":[182],"revealed":[186],"may":[189],"be":[190],"part":[192],"alphaherpesvirus,":[195],"exhibit":[197],"relationship":[200],"with":[201],"simplexvirus.":[206]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}