{"id":"https://openalex.org/W2015488303","doi":"https://doi.org/10.1109/bmei.2009.5305751","title":"Effect of Low Density Lipoprotein Concentration Polarization on Endothelial Cells Adhesion","display_name":"Effect of Low Density Lipoprotein Concentration Polarization on Endothelial Cells Adhesion","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2015488303","doi":"https://doi.org/10.1109/bmei.2009.5305751","mag":"2015488303"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2009.5305751","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5305751","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052724806","display_name":"Dangheng Wei","orcid":"https://orcid.org/0000-0002-2588-0943"},"institutions":[{"id":"https://openalex.org/I91935597","display_name":"University of South China","ror":"https://ror.org/03mqfn238","country_code":"CN","type":"education","lineage":["https://openalex.org/I91935597"]},{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dang-heng Wei","raw_affiliation_strings":["Bioengineering College of Chongqing University, Chongqing, P.R.China","Suzhou University, Suzhou, P.R.China","The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China"],"affiliations":[{"raw_affiliation_string":"Bioengineering College of Chongqing University, Chongqing, P.R.China","institution_ids":["https://openalex.org/I158842170"]},{"raw_affiliation_string":"Suzhou University, Suzhou, P.R.China","institution_ids":[]},{"raw_affiliation_string":"The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China","institution_ids":["https://openalex.org/I91935597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031039660","display_name":"Guixue Wang","orcid":"https://orcid.org/0000-0002-9192-8757"},"institutions":[{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gui-xue Wang","raw_affiliation_strings":["Bioengineering College of Chongqing University, Chongqing, P.R.China"],"affiliations":[{"raw_affiliation_string":"Bioengineering College of Chongqing University, Chongqing, P.R.China","institution_ids":["https://openalex.org/I158842170"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006641020","display_name":"Chaojun Tang","orcid":"https://orcid.org/0000-0001-8927-788X"},"institutions":[{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]},{"id":"https://openalex.org/I91935597","display_name":"University of South China","ror":"https://ror.org/03mqfn238","country_code":"CN","type":"education","lineage":["https://openalex.org/I91935597"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao-jun Tang","raw_affiliation_strings":["Bioengineering College of Chongqing University, Chongqing, P.R.China","The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China"],"affiliations":[{"raw_affiliation_string":"Bioengineering College of Chongqing University, Chongqing, P.R.China","institution_ids":["https://openalex.org/I158842170"]},{"raw_affiliation_string":"The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China","institution_ids":["https://openalex.org/I91935597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034016019","display_name":"Lu-shang Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I91935597","display_name":"University of South China","ror":"https://ror.org/03mqfn238","country_code":"CN","type":"education","lineage":["https://openalex.org/I91935597"]},{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lu-shang Liu","raw_affiliation_strings":["Bioengineering College, Chongqing University, Chongqing, China","The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China"],"affiliations":[{"raw_affiliation_string":"Bioengineering College, Chongqing University, Chongqing, China","institution_ids":["https://openalex.org/I158842170"]},{"raw_affiliation_string":"The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China","institution_ids":["https://openalex.org/I91935597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100636650","display_name":"Zuo Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]},{"id":"https://openalex.org/I91935597","display_name":"University of South China","ror":"https://ror.org/03mqfn238","country_code":"CN","type":"education","lineage":["https://openalex.org/I91935597"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zuo Wang","raw_affiliation_strings":["Bioengineering College, Chongqing University, Chongqing, China","The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China"],"affiliations":[{"raw_affiliation_string":"Bioengineering College, Chongqing University, Chongqing, China","institution_ids":["https://openalex.org/I158842170"]},{"raw_affiliation_string":"The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China","institution_ids":["https://openalex.org/I91935597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002893951","display_name":"Chao\u2010Ke Tang","orcid":null},"institutions":[{"id":"https://openalex.org/I91935597","display_name":"University of South China","ror":"https://ror.org/03mqfn238","country_code":"CN","type":"education","lineage":["https://openalex.org/I91935597"]},{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao-ke Tang","raw_affiliation_strings":["Bioengineering College of Chongqing University, Chongqing, P.R.China","The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China"],"affiliations":[{"raw_affiliation_string":"Bioengineering College of Chongqing University, Chongqing, P.R.China","institution_ids":["https://openalex.org/I158842170"]},{"raw_affiliation_string":"The Institute of Cardiovascular Disease, University of south china, Hengyang, P.R.China","institution_ids":["https://openalex.org/I91935597"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103175299","display_name":"Changgeng Ruan","orcid":"https://orcid.org/0009-0002-5751-8540"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chang-geng Ruan","raw_affiliation_strings":["Suzhou University, Suzhou, P.R.China"],"affiliations":[{"raw_affiliation_string":"Suzhou University, Suzhou, P.R.China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5052724806"],"corresponding_institution_ids":["https://openalex.org/I158842170","https://openalex.org/I91935597"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11595608,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"34","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9879000186920166,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5676451921463013},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.5607342720031738},{"id":"https://openalex.org/keywords/shear-stress","display_name":"Shear stress","score":0.5489646792411804},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.548072874546051},{"id":"https://openalex.org/keywords/low-density-lipoprotein","display_name":"Low-density lipoprotein","score":0.5353119373321533},{"id":"https://openalex.org/keywords/stenosis","display_name":"Stenosis","score":0.518592119216919},{"id":"https://openalex.org/keywords/confocal","display_name":"Confocal","score":0.49278023838996887},{"id":"https://openalex.org/keywords/lipoprotein","display_name":"Lipoprotein","score":0.4892875850200653},{"id":"https://openalex.org/keywords/fluorescence-microscope","display_name":"Fluorescence microscope","score":0.4621468484401703},{"id":"https://openalex.org/keywords/adhesion","display_name":"Adhesion","score":0.45397093892097473},{"id":"https://openalex.org/keywords/confocal-laser-scanning-microscopy","display_name":"Confocal laser scanning microscopy","score":0.4350703954696655},{"id":"https://openalex.org/keywords/concentration-polarization","display_name":"Concentration polarization","score":0.4329097867012024},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.38098835945129395},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.354560524225235},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.3362444043159485},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.2839064300060272},{"id":"https://openalex.org/keywords/cholesterol","display_name":"Cholesterol","score":0.2034582793712616},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1658833622932434},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.14773160219192505},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.13301503658294678},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11764290928840637},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.08636492490768433}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5676451921463013},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5607342720031738},{"id":"https://openalex.org/C21141959","wikidata":"https://www.wikidata.org/wiki/Q657936","display_name":"Shear stress","level":2,"score":0.5489646792411804},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.548072874546051},{"id":"https://openalex.org/C2779620165","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Low-density lipoprotein","level":3,"score":0.5353119373321533},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.518592119216919},{"id":"https://openalex.org/C136009344","wikidata":"https://www.wikidata.org/wiki/Q336201","display_name":"Confocal","level":2,"score":0.49278023838996887},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4892875850200653},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.4621468484401703},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.45397093892097473},{"id":"https://openalex.org/C88412794","wikidata":"https://www.wikidata.org/wiki/Q902045","display_name":"Confocal laser scanning microscopy","level":2,"score":0.4350703954696655},{"id":"https://openalex.org/C38115104","wikidata":"https://www.wikidata.org/wiki/Q582852","display_name":"Concentration polarization","level":3,"score":0.4329097867012024},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38098835945129395},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.354560524225235},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3362444043159485},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.2839064300060272},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.2034582793712616},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1658833622932434},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.14773160219192505},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13301503658294678},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11764290928840637},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.08636492490768433},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2009.5305751","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5305751","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1955961319","https://openalex.org/W1980238635","https://openalex.org/W2020773684","https://openalex.org/W2104526102","https://openalex.org/W2130769819","https://openalex.org/W2164648100","https://openalex.org/W2181525610","https://openalex.org/W2230778320","https://openalex.org/W6686019696"],"related_works":["https://openalex.org/W3046954146","https://openalex.org/W4251062730","https://openalex.org/W2007276746","https://openalex.org/W2370899043","https://openalex.org/W2586464062","https://openalex.org/W2373707877","https://openalex.org/W2392239448","https://openalex.org/W2368020487","https://openalex.org/W2760090091","https://openalex.org/W2391522739"],"abstract_inverted_index":{"To":[0],"test":[1],"the":[2,13,18,37,77,85,96,111,124,144,153],"hypothesis":[3],"that":[4,76],"concentration":[5,35,81,93,138],"polarization":[6,139],"of":[7,20,39,100,128,140,147,155],"atherogenic":[8],"lipids":[9],"may":[10],"occur":[11],"in":[12,150],"arterial":[14],"system":[15],"and":[16,46,66,98,126,149],"probe":[17],"effect":[19,152],"endothelial":[21],"cells":[22],"(ECs).":[23],"A":[24],"modifier":[25],"with":[26,43,55,95,110,116],"local":[27],"stenosis":[28,40],"was":[29,41,47,68,82,106,120],"developed.":[30],"The":[31,88,102],"luminal":[32,78,90],"surface":[33,79,91],"LDL":[34,80,92,134,141],"at":[36,143],"distal":[38,145],"analyzed":[42],"numerical":[44,112],"stimulation":[45,74],"measured":[48],"by":[49,70],"confocal":[50],"microscopy.":[51],"ECs":[52,60,129,156],"were":[53,61,130],"incubated":[54],"low":[56],"density":[57],"lipoprotein(LDL).":[58],"Then,":[59],"exposed":[62],"to":[63,133],"shear":[64],"stress(15dyn/cm2)":[65],"F-actin":[67,118],"examined":[69],"fluorescence":[71],"staining.":[72],"Numerical":[73],"showed":[75],"higher":[83],"than":[84],"bulk":[86],"concentration.":[87,135],"relative":[89,132],"varied":[94],"velocity":[97],"degree":[99],"stenosis.":[101],"experimental":[103],"detection":[104],"result":[105],"very":[107],"good":[108],"agreement":[109],"analysis.":[113],"After":[114],"treated":[115],"LDL,":[117],"reorganization":[119],"observed.":[121],"Under":[122],"flow,":[123],"adhesion":[125,154],"retention":[127],"negatively":[131],"Therefore":[136],"provided":[137],"occurs":[142],"end":[146],"stenosis,":[148],"turn":[151],"under":[157],"flow.":[158]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}