{"id":"https://openalex.org/W2136613887","doi":"https://doi.org/10.1109/bmei.2009.5305388","title":"The Design of a High Efficient DNA In-Situ Synthesis Apparatus Based on the Principle of Typography Technique","display_name":"The Design of a High Efficient DNA In-Situ Synthesis Apparatus Based on the Principle of Typography Technique","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2136613887","doi":"https://doi.org/10.1109/bmei.2009.5305388","mag":"2136613887"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2009.5305388","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5305388","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100320305","display_name":"Wen Li","orcid":"https://orcid.org/0000-0002-6807-479X"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wen Li","raw_affiliation_strings":["Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108714148","display_name":"Jiandi He","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiandi He","raw_affiliation_strings":["Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024189982","display_name":"Pei Jiang","orcid":"https://orcid.org/0000-0002-8360-7427"},"institutions":[{"id":"https://openalex.org/I49934816","display_name":"Hunan University of Technology","ror":"https://ror.org/04j3vr751","country_code":"CN","type":"education","lineage":["https://openalex.org/I49934816"]},{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pei Jiang","raw_affiliation_strings":["Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China","Key laboratory of Green packaging and Application of Biological Nanotechnology of Hunan Province, Hunan University of Technology, Zhuzhou, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Key laboratory of Green packaging and Application of Biological Nanotechnology of Hunan Province, Hunan University of Technology, Zhuzhou, China","institution_ids":["https://openalex.org/I49934816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046015280","display_name":"Xiaoxi Zeng","orcid":"https://orcid.org/0000-0001-9946-4291"},"institutions":[{"id":"https://openalex.org/I49934816","display_name":"Hunan University of Technology","ror":"https://ror.org/04j3vr751","country_code":"CN","type":"education","lineage":["https://openalex.org/I49934816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxi Zeng","raw_affiliation_strings":["Key laboratory of Green Packaging and Application of Biological Nanotechnology of Hunan Province, Hunan University of Technology, Zhuzhou, China"],"affiliations":[{"raw_affiliation_string":"Key laboratory of Green Packaging and Application of Biological Nanotechnology of Hunan Province, Hunan University of Technology, Zhuzhou, China","institution_ids":["https://openalex.org/I49934816"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083322793","display_name":"Jianxin Tang","orcid":"https://orcid.org/0000-0002-6813-0448"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I49934816","display_name":"Hunan University of Technology","ror":"https://ror.org/04j3vr751","country_code":"CN","type":"education","lineage":["https://openalex.org/I49934816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Tang","raw_affiliation_strings":["Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China","Key laboratory of Green Packaging and Application of Biological Nanotechnology of Hunan Province, Hunan University of Technology, Zhuzhou, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Info-physics and Geomatics Engineering, Central South University, Changsha, China","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Key laboratory of Green Packaging and Application of Biological Nanotechnology of Hunan Province, Hunan University of Technology, Zhuzhou, China","institution_ids":["https://openalex.org/I49934816"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100320305"],"corresponding_institution_ids":["https://openalex.org/I139660479"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15161012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"50","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9817000031471252,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.978600025177002,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biochip","display_name":"Biochip","score":0.851425051689148},{"id":"https://openalex.org/keywords/typography","display_name":"Typography","score":0.5708264708518982},{"id":"https://openalex.org/keywords/computer-hardware","display_name":"Computer hardware","score":0.5599812269210815},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.540009617805481},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.3938853442668915},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.24794051051139832},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.21334323287010193}],"concepts":[{"id":"https://openalex.org/C87892846","wikidata":"https://www.wikidata.org/wiki/Q864256","display_name":"Biochip","level":2,"score":0.851425051689148},{"id":"https://openalex.org/C166422571","wikidata":"https://www.wikidata.org/wiki/Q159964","display_name":"Typography","level":2,"score":0.5708264708518982},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.5599812269210815},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.540009617805481},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.3938853442668915},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.24794051051139832},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.21334323287010193},{"id":"https://openalex.org/C153349607","wikidata":"https://www.wikidata.org/wiki/Q36649","display_name":"Visual arts","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2009.5305388","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5305388","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1511902998","https://openalex.org/W1967053372","https://openalex.org/W1970156673","https://openalex.org/W1986257287","https://openalex.org/W2020720485","https://openalex.org/W2052416995","https://openalex.org/W2089749945","https://openalex.org/W2091775855","https://openalex.org/W2106586614","https://openalex.org/W2108914491","https://openalex.org/W2119274294","https://openalex.org/W2121752230","https://openalex.org/W2130301347","https://openalex.org/W2225755153"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2364922518","https://openalex.org/W2361860382","https://openalex.org/W1995422305","https://openalex.org/W2379531326","https://openalex.org/W2604557458","https://openalex.org/W2544485685","https://openalex.org/W1834829329","https://openalex.org/W2353006359","https://openalex.org/W2599588613"],"abstract_inverted_index":{"The":[0,44,108],"paper":[1],"describes":[2],"a":[3],"novel":[4],"machine":[5,104],"for":[6,26],"in-situ":[7],"synthesis":[8,57,122],"of":[9,16,71,81,91,102,119,123,129],"DNA":[10],"Micro-arrays":[11],"based":[12,125],"on":[13,126],"the":[14,64,68,79,98,112,117,127],"use":[15],"typography":[17,130],"technique.":[18],"This":[19],"apparatus":[20],"was":[21,48],"designed":[22],"to":[23,50],"incorporate":[24],"platform":[25],"imprinting,":[27,61],"precision":[28,70],"printing":[29,92,100],"stencil,":[30],"one-way":[31],"positioning":[32],"device,":[33],"manipulator,":[34],"and":[35,41,60,62,97],"liquid":[36],"&":[37],"gas":[38],"delivery":[39],"part":[40],"control":[42,51,69],"part.":[43],"programmable":[45],"logic":[46],"controller":[47],"employed":[49],"operation":[52],"steps":[53],"involving":[54],"in":[55,83,120],"biochip":[56,124],"including":[58],"locating":[59],"delivering":[63],"specific":[65],"liquid.":[66],"Finally,":[67],"system":[72],"is":[73,87,94,105],"measured":[74],"using":[75],"three":[76],"coordinated":[77],"instrument:":[78],"accuracy":[80,90,101],"location":[82],"X,":[84],"Y":[85],"axis":[86],"5":[88],"mum,":[89,96],"template":[93],"7":[95],"repeated":[99],"whole":[103],"16":[106],"mum.":[107],"result":[109],"indicates":[110],"that":[111],"design":[113],"can":[114],"completely":[115],"meet":[116],"requirement":[118],"situ":[121],"principle":[128],"printing.":[131]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}