{"id":"https://openalex.org/W2103609050","doi":"https://doi.org/10.1109/bmei.2009.5305045","title":"Characterization of Codon Usage Bias in the Newly Identified DPV gE Gene","display_name":"Characterization of Codon Usage Bias in the Newly Identified DPV gE Gene","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2103609050","doi":"https://doi.org/10.1109/bmei.2009.5305045","mag":"2103609050"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2009.5305045","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5305045","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110086628","display_name":"Hua Chang","orcid":null},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hua Chang","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045418032","display_name":"Anchun Cheng","orcid":"https://orcid.org/0000-0001-6093-353X"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anchun Cheng","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102002022","display_name":"Mingshu Wang","orcid":"https://orcid.org/0000-0001-9652-392X"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingshu Wang","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061775199","display_name":"Wei Xie","orcid":"https://orcid.org/0000-0003-2126-3849"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Xie","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102707644","display_name":"Jun Xiang","orcid":"https://orcid.org/0000-0003-2271-7208"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Xiang","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030658417","display_name":"Kunpeng Lou","orcid":null},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kunpeng Lou","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019975620","display_name":"Mingsheng Cai","orcid":"https://orcid.org/0000-0002-9197-3101"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingsheng Cai","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045418032","display_name":"Anchun Cheng","orcid":"https://orcid.org/0000-0001-6093-353X"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anchun Cheng","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102002022","display_name":"Mingshu Wang","orcid":"https://orcid.org/0000-0001-9652-392X"},"institutions":[{"id":"https://openalex.org/I37574244","display_name":"Sichuan Agricultural University","ror":"https://ror.org/0388c3403","country_code":"CN","type":"education","lineage":["https://openalex.org/I37574244"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingshu Wang","raw_affiliation_strings":["Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China"],"affiliations":[{"raw_affiliation_string":"Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, China","institution_ids":["https://openalex.org/I37574244"]},{"raw_affiliation_string":"Key Laboratory of Animal Diseases and Human Health of Sichuan Province, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China","institution_ids":["https://openalex.org/I37574244"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5110086628"],"corresponding_institution_ids":["https://openalex.org/I37574244"],"apc_list":null,"apc_paid":null,"fwci":1.0498,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.75935887,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"276","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/codon-usage-bias","display_name":"Codon usage bias","score":0.808453381061554},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6667345762252808},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5262873768806458},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4950639307498932},{"id":"https://openalex.org/keywords/molecular-biology","display_name":"Molecular biology","score":0.3506465554237366},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.22773471474647522}],"concepts":[{"id":"https://openalex.org/C87253356","wikidata":"https://www.wikidata.org/wiki/Q1106472","display_name":"Codon usage bias","level":4,"score":0.808453381061554},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6667345762252808},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5262873768806458},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4950639307498932},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3506465554237366},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.22773471474647522}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2009.5305045","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5305045","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7099999785423279}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W193446248","https://openalex.org/W1489817806","https://openalex.org/W1550695177","https://openalex.org/W1866610019","https://openalex.org/W1951333111","https://openalex.org/W1966773394","https://openalex.org/W1968914986","https://openalex.org/W1969317756","https://openalex.org/W1970233137","https://openalex.org/W1970245110","https://openalex.org/W1971707621","https://openalex.org/W1972482543","https://openalex.org/W1974358663","https://openalex.org/W1975283698","https://openalex.org/W1975431806","https://openalex.org/W1977566832","https://openalex.org/W1978097322","https://openalex.org/W1989529069","https://openalex.org/W1993293753","https://openalex.org/W1996050521","https://openalex.org/W1996761892","https://openalex.org/W2000269014","https://openalex.org/W2002677631","https://openalex.org/W2004146038","https://openalex.org/W2004674004","https://openalex.org/W2012063247","https://openalex.org/W2018210964","https://openalex.org/W2018590530","https://openalex.org/W2019012467","https://openalex.org/W2019034056","https://openalex.org/W2019604065","https://openalex.org/W2035815009","https://openalex.org/W2037902594","https://openalex.org/W2042782470","https://openalex.org/W2043178000","https://openalex.org/W2050115910","https://openalex.org/W2051043527","https://openalex.org/W2056268170","https://openalex.org/W2059628904","https://openalex.org/W2059661284","https://openalex.org/W2060020017","https://openalex.org/W2061249175","https://openalex.org/W2064810946","https://openalex.org/W2065120930","https://openalex.org/W2070765702","https://openalex.org/W2072284352","https://openalex.org/W2077046573","https://openalex.org/W2080418977","https://openalex.org/W2084550371","https://openalex.org/W2094859009","https://openalex.org/W2106201948","https://openalex.org/W2109244138","https://openalex.org/W2110236168","https://openalex.org/W2126367720","https://openalex.org/W2127543611","https://openalex.org/W2132644745","https://openalex.org/W2132836838","https://openalex.org/W2133238953","https://openalex.org/W2140261743","https://openalex.org/W2149227633","https://openalex.org/W2154278477","https://openalex.org/W2159349026","https://openalex.org/W2159365979","https://openalex.org/W2163050240","https://openalex.org/W2164618276","https://openalex.org/W2167395325","https://openalex.org/W2169191388","https://openalex.org/W2371354124","https://openalex.org/W4285719527","https://openalex.org/W6640675529","https://openalex.org/W6676666510","https://openalex.org/W6682010768"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W1966015348","https://openalex.org/W2102511336","https://openalex.org/W2921764584","https://openalex.org/W1866610019"],"abstract_inverted_index":{"The":[0,34,62],"Duck":[1],"Plague":[2],"Virus":[3],"(DPV)":[4],"gE":[5,23,44,71,92,125,136],"gene":[6,24,45,72,93,101,104,137],"was":[7,46,73,138],"identified":[8],"by":[9,25],"constructing":[10],"the":[11,18,42,50,58,69,81,86,120,123,130],"DPV":[12,22,43,70,91,124,135,157,163,170],"genomic":[13],"library,":[14],"and":[15,29,55,103,129,146,158,164,171],"we":[16],"analyzed":[17],"codon":[19,38,60,65,87,131],"usage":[20,39,66,88,132,154],"of":[21,32,90,122,134,142],"using":[26],"CAI,":[27],"CHIPS":[28],"CUSP":[30],"program":[31],"EMBOSS.":[33],"results":[35],"showed":[36,111],"that":[37,85,112],"bias":[40,48,67,89,133],"in":[41,68,119],"strong":[47],"towards":[49],"synonymous":[51],"codons":[52,151,168],"with":[53,75,99,140],"A":[54],"T":[56],"at":[57],"third":[59],"position.":[61],"amino":[63],"acids":[64],"compared":[74,139],"other":[76],"15":[77,167],"reference":[78],"herpes":[79],"viruses,":[80],"cluster":[82],"analysis":[83,110],"demonstrated":[84],"has":[94],"a":[95],"very":[96],"close":[97],"relation":[98],"its":[100],"function":[102],"type.":[105],"In":[106],"addition,":[107],"rare":[108,116],"condons":[109,117],"there":[113],"are":[114,149],"62":[115],"(33.3%)":[118],"ORF":[121],"on":[126],"line":[127],"(http//:www.kazusa.or.jp/codon),":[128],"those":[141],"E.":[143,159],"coli,":[144,160],"yeast":[145],"Humans.":[147],"There":[148],"24":[150],"showing":[152],"distinct":[153],"differences":[155],"between":[156,162,169],"19":[161],"Homo":[165],"sapiens,":[166],"yeast.":[172]},"counts_by_year":[{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}