{"id":"https://openalex.org/W2156669119","doi":"https://doi.org/10.1109/bmei.2009.5302819","title":"PROBER: Segmentation and Differential Analysis Tool for Tiling Microarray Data","display_name":"PROBER: Segmentation and Differential Analysis Tool for Tiling Microarray Data","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2156669119","doi":"https://doi.org/10.1109/bmei.2009.5302819","mag":"2156669119"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2009.5302819","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5302819","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111373172","display_name":"Guoli Ji","orcid":null},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guoli Ji","raw_affiliation_strings":["Department of Automation, Xiamen University, Xiamen, Fujian, China"],"affiliations":[{"raw_affiliation_string":"Department of Automation, Xiamen University, Xiamen, Fujian, China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091165765","display_name":"Xiaohui Wu","orcid":"https://orcid.org/0000-0003-0356-7785"},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaohui Wu","raw_affiliation_strings":["Department of Automation, Xiamen University, Xiamen, Fujian, China"],"affiliations":[{"raw_affiliation_string":"Department of Automation, Xiamen University, Xiamen, Fujian, China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001863695","display_name":"Denghui Xing","orcid":"https://orcid.org/0000-0003-0283-4247"},"institutions":[{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Denghui Xing","raw_affiliation_strings":["Department of Botany, Miami University, Oxford, OH, USA"],"affiliations":[{"raw_affiliation_string":"Department of Botany, Miami University, Oxford, OH, USA","institution_ids":["https://openalex.org/I83328450"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011758500","display_name":"Qingshun Quinn Li","orcid":"https://orcid.org/0000-0003-4105-1480"},"institutions":[{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qingshun Quinn Li","raw_affiliation_strings":["Department of Botany, Miami University, Oxford, OH, USA"],"affiliations":[{"raw_affiliation_string":"Department of Botany, Miami University, Oxford, OH, USA","institution_ids":["https://openalex.org/I83328450"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5111373172"],"corresponding_institution_ids":["https://openalex.org/I191208505"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15680679,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9912999868392944,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9854999780654907,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microarray-databases","display_name":"Microarray databases","score":0.7492406368255615},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.6421226263046265},{"id":"https://openalex.org/keywords/gene-chip-analysis","display_name":"Gene chip analysis","score":0.5970445275306702},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5369081497192383},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.531446635723114},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5130190253257751},{"id":"https://openalex.org/keywords/gene-annotation","display_name":"Gene Annotation","score":0.47615528106689453},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.47220784425735474},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.47134730219841003},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.46714919805526733},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.4537220299243927},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.44735419750213623},{"id":"https://openalex.org/keywords/tiling-array","display_name":"Tiling array","score":0.4350617229938507},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4018588066101074},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3429047465324402},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.3286636769771576},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2539208233356476},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16092899441719055}],"concepts":[{"id":"https://openalex.org/C548314002","wikidata":"https://www.wikidata.org/wiki/Q6839218","display_name":"Microarray databases","level":5,"score":0.7492406368255615},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.6421226263046265},{"id":"https://openalex.org/C24361400","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Gene chip analysis","level":5,"score":0.5970445275306702},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5369081497192383},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.531446635723114},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5130190253257751},{"id":"https://openalex.org/C2908923196","wikidata":"https://www.wikidata.org/wiki/Q5205742","display_name":"Gene Annotation","level":4,"score":0.47615528106689453},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.47220784425735474},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.47134730219841003},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.46714919805526733},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.4537220299243927},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.44735419750213623},{"id":"https://openalex.org/C119401833","wikidata":"https://www.wikidata.org/wiki/Q7802158","display_name":"Tiling array","level":5,"score":0.4350617229938507},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4018588066101074},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3429047465324402},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3286636769771576},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2539208233356476},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16092899441719055}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2009.5302819","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5302819","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1547068196","https://openalex.org/W1559899545","https://openalex.org/W2007654074","https://openalex.org/W2056696298","https://openalex.org/W2060585570","https://openalex.org/W2066157914","https://openalex.org/W2129429612","https://openalex.org/W2134597218","https://openalex.org/W2140022443","https://openalex.org/W2140303894","https://openalex.org/W2162916842","https://openalex.org/W2170989872"],"related_works":["https://openalex.org/W2160130936","https://openalex.org/W2186624854","https://openalex.org/W2412120523","https://openalex.org/W2498363374","https://openalex.org/W1547158732","https://openalex.org/W3154327893","https://openalex.org/W2409073243","https://openalex.org/W1594655861","https://openalex.org/W2490137852","https://openalex.org/W1991841244"],"abstract_inverted_index":{"Identification":[0],"of":[1,11,35,52,60,75,95,119,137],"gene":[2,36,84,89,105,140],"structures":[3,85],"is":[4,15,64,80,101],"key":[5],"to":[6,17,39,82,103,115],"genome":[7,22],"annotation,":[8],"and":[9,21,45,54,86,109,129,134,142],"analysis":[10,34,59,74],"alternative":[12,143],"RNA":[13,144],"processing":[14,145],"critical":[16],"understand":[18],"transcriptome":[19],"diversity":[20],"coding":[23],"capacity.":[24],"Tiling":[25],"microarray":[26,62,78,96,127],"has":[27],"become":[28],"an":[29],"important":[30],"tool":[31,71],"for":[32,48,72],"genome-wide":[33],"expression":[37,118],"due":[38],"its":[40],"high":[41,43],"resolution,":[42],"density":[44],"throughput.":[46],"However,":[47],"the":[49],"huge":[50],"volume":[51],"data":[53,63],"limited":[55],"probe":[56],"design":[57],"options,":[58],"tiling":[61,77,126],"neither":[65],"easy":[66],"nor":[67],"effective.":[68],"PROBER,":[69,92],"a":[70],"integrated":[73],"massive":[76],"data,":[79,97],"developed":[81],"identify":[83,104],"analyze":[87,116],"differential":[88,117],"expression.":[90],"In":[91],"after":[93],"normalization":[94],"structural":[98],"change":[99],"model":[100],"used":[102],"structures.":[106],"T-Test,":[107],"wavelet":[108],"other":[110],"methods":[111],"are":[112,146],"then":[113],"adopted":[114],"genes":[120],"under":[121],"different":[122],"conditions.":[123],"By":[124],"combining":[125],"technology":[128],"applying":[130],"computer":[131],"recognition":[132],"models":[133],"algorithms,":[135],"applications":[136],"PROBER":[138],"in":[139],"annotation":[141],"demonstrated.":[147]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}