{"id":"https://openalex.org/W4409020064","doi":"https://doi.org/10.1109/bigcomp64353.2025.00026","title":"Alu as the Driver of CNV Formation: A Computational Approach to Reveal NAHR","display_name":"Alu as the Driver of CNV Formation: A Computational Approach to Reveal NAHR","publication_year":2025,"publication_date":"2025-02-09","ids":{"openalex":"https://openalex.org/W4409020064","doi":"https://doi.org/10.1109/bigcomp64353.2025.00026"},"language":"en","primary_location":{"id":"doi:10.1109/bigcomp64353.2025.00026","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bigcomp64353.2025.00026","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Big Data and Smart Computing (BigComp)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104252196","display_name":"Charyeong Heo","orcid":null},"institutions":[{"id":"https://openalex.org/I24062138","display_name":"Konkuk University","ror":"https://ror.org/025h1m602","country_code":"KR","type":"education","lineage":["https://openalex.org/I24062138"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Charyeong Heo","raw_affiliation_strings":["Konkuk University,Department of Biomedical Science and Engineering,Seoul,Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Konkuk University,Department of Biomedical Science and Engineering,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I24062138"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nayoung Park","orcid":null},"institutions":[{"id":"https://openalex.org/I24062138","display_name":"Konkuk University","ror":"https://ror.org/025h1m602","country_code":"KR","type":"education","lineage":["https://openalex.org/I24062138"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Nayoung Park","raw_affiliation_strings":["Konkuk University,Department of Biomedical Science and Engineering,Seoul,Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Konkuk University,Department of Biomedical Science and Engineering,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I24062138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113322250","display_name":"Jaebum Kim","orcid":null},"institutions":[{"id":"https://openalex.org/I24062138","display_name":"Konkuk University","ror":"https://ror.org/025h1m602","country_code":"KR","type":"education","lineage":["https://openalex.org/I24062138"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jaebum Kim","raw_affiliation_strings":["Konkuk University,Department of Biomedical Science and Engineering,Seoul,Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Konkuk University,Department of Biomedical Science and Engineering,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I24062138"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5104252196"],"corresponding_institution_ids":["https://openalex.org/I24062138"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.093695,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"92","last_page":"93"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.5410000085830688,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.5410000085830688,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.4726000130176544,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12055","display_name":"Boron Compounds in Chemistry","score":0.4343999922275543,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6548563838005066}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6548563838005066}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bigcomp64353.2025.00026","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bigcomp64353.2025.00026","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Big Data and Smart Computing (BigComp)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6499999761581421,"id":"https://metadata.un.org/sdg/13","display_name":"Climate action"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W2096128575","https://openalex.org/W2102619694","https://openalex.org/W2162927194","https://openalex.org/W2166657289","https://openalex.org/W2180834397","https://openalex.org/W3127238141","https://openalex.org/W4309665152","https://openalex.org/W4386846548"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Copy":[0],"Number":[1],"Variations":[2],"(CNVs)":[3],"are":[4],"genomic":[5,66],"alterations":[6],"characterized":[7],"by":[8],"the":[9,23,40,51],"gain":[10],"or":[11],"loss":[12],"of":[13,25,42,50],"DNA":[14],"segments,":[15],"which":[16],"impact":[17],"gene":[18],"function":[19],"and":[20,32],"expression.":[21],"Understanding":[22],"mechanisms":[24],"CNV":[26,55],"formation":[27],"is":[28],"essential":[29],"for":[30,54],"predicting":[31],"preventing":[33],"CNV-mediated":[34],"disease":[35],"development.":[36],"This":[37],"study":[38],"investigates":[39],"role":[41],"Alus":[43],"in":[44,74],"Non-allelic":[45],"Homologous":[46],"Recombination":[47],"(NAHR),":[48],"one":[49],"primary":[52],"pathways":[53],"formation.":[56],"Additionally,":[57],"a":[58,69],"multi-modal":[59],"Convolutional":[60],"Neural":[61],"Network":[62],"(CNN)":[63],"analysis":[64],"identified":[65],"composition":[67],"as":[68],"key":[70],"determinant":[71],"influencing":[72],"NAHR":[73],"Alus.":[75]},"counts_by_year":[],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}