{"id":"https://openalex.org/W3128439880","doi":"https://doi.org/10.1109/bibm49941.2020.9313384","title":"Using bioinformatics methods to explore the connections between expression and subcellular localization of proteins and gastric cancer progression","display_name":"Using bioinformatics methods to explore the connections between expression and subcellular localization of proteins and gastric cancer progression","publication_year":2020,"publication_date":"2020-12-16","ids":{"openalex":"https://openalex.org/W3128439880","doi":"https://doi.org/10.1109/bibm49941.2020.9313384","mag":"3128439880"},"language":"en","primary_location":{"id":"doi:10.1109/bibm49941.2020.9313384","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm49941.2020.9313384","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039856495","display_name":"Zhenying Tang","orcid":null},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenying Tang","raw_affiliation_strings":["College of computer science, Sichuan University, Chengdu, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of computer science, Sichuan University, Chengdu, PR China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101717292","display_name":"Ming Xiao","orcid":"https://orcid.org/0000-0001-8608-5903"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Xiao","raw_affiliation_strings":["College of computer science, Sichuan University, Chengdu, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of computer science, Sichuan University, Chengdu, PR China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004289873","display_name":"Senyi Deng","orcid":"https://orcid.org/0000-0002-3278-3375"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Senyi Deng","raw_affiliation_strings":["Thoracic Surgery Research Laboratory, Sichuan University, Chengdu, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Surgery Research Laboratory, Sichuan University, Chengdu, PR China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100350625","display_name":"Le Zhang","orcid":"https://orcid.org/0000-0002-3708-1727"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Le Zhang","raw_affiliation_strings":["Medical Big Data Center, Sichuan University, Chengdu, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Big Data Center, Sichuan University, Chengdu, PR China","institution_ids":["https://openalex.org/I24185976"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I24185976"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13607697,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1862","last_page":"1869"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subcellular-localization","display_name":"Subcellular localization","score":0.6312822699546814},{"id":"https://openalex.org/keywords/protein-expression","display_name":"Protein expression","score":0.5471649169921875},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5247179269790649},{"id":"https://openalex.org/keywords/suppressor","display_name":"Suppressor","score":0.5131088495254517},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4666571319103241},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.45747753977775574},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.42015784978866577},{"id":"https://openalex.org/keywords/men1","display_name":"MEN1","score":0.41285401582717896},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.40327560901641846},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3778145909309387},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.212185800075531}],"concepts":[{"id":"https://openalex.org/C2776879804","wikidata":"https://www.wikidata.org/wiki/Q7630919","display_name":"Subcellular localization","level":3,"score":0.6312822699546814},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.5471649169921875},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5247179269790649},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.5131088495254517},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4666571319103241},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45747753977775574},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.42015784978866577},{"id":"https://openalex.org/C2779469564","wikidata":"https://www.wikidata.org/wiki/Q1920577","display_name":"MEN1","level":4,"score":0.41285401582717896},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40327560901641846},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3778145909309387},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.212185800075531},{"id":"https://openalex.org/C2780103800","wikidata":"https://www.wikidata.org/wiki/Q1553018","display_name":"Multiple endocrine neoplasia","level":3,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/bibm49941.2020.9313384","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm49941.2020.9313384","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/f69760a0-4097-431f-9056-1c100240b0b6","is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/f69760a0-4097-431f-9056-1c100240b0b6","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tang, Z, Xiao, M, Deng, S & Zhang, L 2020, Using bioinformatics methods to explore the connections between expression and subcellular localization of proteins and gastric cancer progression. in Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020. Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020, Institute of Electrical and Electronics Engineers Inc., pp. 1862-1869, 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020, Virtual, Seoul, South Korea, 16/12/2020. https://doi.org/10.1109/BIBM49941.2020.9313384","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/2ed8a264-1ba2-4dca-8a92-8ee03f97888f","is_oa":false,"landing_page_url":"https://pure.amc.nl/en/publications/using-bioinformatics-methods-to-explore-the-connections-between-expression-and-subcellular-localization-of-proteins-and-gastric-cancer-progression(2ed8a264-1ba2-4dca-8a92-8ee03f97888f).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020, 1862 - 1869","raw_type":"info:eu-repo/semantics/conferencepaper"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8399999737739563,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320322990","display_name":"Sichuan University","ror":"https://ror.org/011ashp19"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1836699425","https://openalex.org/W1973695309","https://openalex.org/W1998137132","https://openalex.org/W2012034410","https://openalex.org/W2064394610","https://openalex.org/W2076424456","https://openalex.org/W2095027401","https://openalex.org/W2115899293","https://openalex.org/W2144548050","https://openalex.org/W2145495465","https://openalex.org/W2158485828","https://openalex.org/W2167284467","https://openalex.org/W2169286052","https://openalex.org/W2169480788","https://openalex.org/W2172854830","https://openalex.org/W2175791037","https://openalex.org/W2217040685","https://openalex.org/W2321471970","https://openalex.org/W2327496372","https://openalex.org/W2466335605","https://openalex.org/W2565501821","https://openalex.org/W2583212256","https://openalex.org/W2611893941","https://openalex.org/W2738707880","https://openalex.org/W2744888710","https://openalex.org/W2749613778","https://openalex.org/W2808756190","https://openalex.org/W2871790448","https://openalex.org/W2884763448","https://openalex.org/W2884813961","https://openalex.org/W2894614073","https://openalex.org/W2965079766","https://openalex.org/W3010221055","https://openalex.org/W3026010813","https://openalex.org/W3136918052"],"related_works":["https://openalex.org/W2045734537","https://openalex.org/W4394855541","https://openalex.org/W3091729188","https://openalex.org/W2944670509","https://openalex.org/W1686772828","https://openalex.org/W2037994546","https://openalex.org/W582584128","https://openalex.org/W1977242871","https://openalex.org/W2157950181","https://openalex.org/W2072520846"],"abstract_inverted_index":{"Since":[0],"the":[1,8,18,34,43,62,76,80],"expression":[2,47,66],"and":[3,24],"localization":[4],"of":[5,45,64,82],"protein":[6],"plays":[7],"important":[9],"role":[10],"for":[11],"GC,":[12],"this":[13],"study":[14],"is":[15,91],"to":[16,32],"explore":[17],"connections":[19],"between":[20],"these":[21],"proteomic":[22],"information":[23],"GC":[25,50,69],"prognosis.":[26,100],"After":[27],"we":[28,40],"use":[29],"bioinformatics":[30],"method":[31],"analyze":[33],"dataset":[35],"from":[36],"Human":[37],"Protein":[38],"Atlas,":[39],"found":[41],"that":[42,97],"proportions":[44],"high":[46],"intensity":[48,67],"in":[49,55,68,74,79],"are":[51,70,85],"less":[52],"than":[53,72,88],"those":[54,73],"normal":[56,83],"stomach":[57],"tissue":[58],"(NST)":[59],"samples,":[60],"whereas":[61],"proportion":[63],"low":[65],"greater":[71],"NST;":[75],"proteins":[77],"located":[78],"nucleus":[81],"cells":[84],"more":[86],"stable":[87],"others;":[89],"MEN1":[90],"such":[92],"a":[93],"tumor":[94],"suppressor":[95],"gene":[96],"has":[98],"favorable":[99]},"counts_by_year":[],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2025-10-10T00:00:00"}