{"id":"https://openalex.org/W1986738324","doi":"https://doi.org/10.1109/bibm.2014.6999144","title":"NovoPair: De novo peptide sequencing for tandem mass spectra pair","display_name":"NovoPair: De novo peptide sequencing for tandem mass spectra pair","publication_year":2014,"publication_date":"2014-11-01","ids":{"openalex":"https://openalex.org/W1986738324","doi":"https://doi.org/10.1109/bibm.2014.6999144","mag":"1986738324"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2014.6999144","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2014.6999144","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100395018","display_name":"Yan Yan","orcid":"https://orcid.org/0000-0001-5404-5026"},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Yan Yan","raw_affiliation_strings":["Division of Biomedical Engineering, University of Saskatchewan Saskatoon, Canada","Division of Biomedical Engineering, University of Saskatchewan, Saskatoon SK S7N 5A9, Canada#TAB#"],"affiliations":[{"raw_affiliation_string":"Division of Biomedical Engineering, University of Saskatchewan Saskatoon, Canada","institution_ids":["https://openalex.org/I32625721"]},{"raw_affiliation_string":"Division of Biomedical Engineering, University of Saskatchewan, Saskatoon SK S7N 5A9, Canada#TAB#","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034538230","display_name":"Anthony Kusalik","orcid":"https://orcid.org/0000-0001-9278-8859"},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Anthony J. Kusalik","raw_affiliation_strings":["Department of Computer Science, University of Saskatchewan Saskatoon, Canada","Department of Computer Science, Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Saskatchewan Saskatoon, Canada","institution_ids":["https://openalex.org/I32625721"]},{"raw_affiliation_string":"Department of Computer Science, Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada","institution_ids":["https://openalex.org/I32625721"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091157395","display_name":"Fang\u2010Xiang Wu","orcid":"https://orcid.org/0000-0002-4593-9332"},"institutions":[{"id":"https://openalex.org/I32625721","display_name":"University of Saskatchewan","ror":"https://ror.org/010x8gc63","country_code":"CA","type":"education","lineage":["https://openalex.org/I32625721"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Fang-Xiang Wu","raw_affiliation_strings":["Division of Biomedical Engineering, University of Saskatchewan Saskatoon, Canada","Division of Biomedical Engineering, Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9 Canada"],"affiliations":[{"raw_affiliation_string":"Division of Biomedical Engineering, University of Saskatchewan Saskatoon, Canada","institution_ids":["https://openalex.org/I32625721"]},{"raw_affiliation_string":"Division of Biomedical Engineering, Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9 Canada","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100395018"],"corresponding_institution_ids":["https://openalex.org/I32625721"],"apc_list":null,"apc_paid":null,"fwci":0.6325,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.6405,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"150","last_page":"155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tandem-mass-spectrometry","display_name":"Tandem mass spectrometry","score":0.7165480256080627},{"id":"https://openalex.org/keywords/electron-transfer-dissociation","display_name":"Electron-transfer dissociation","score":0.7134720087051392},{"id":"https://openalex.org/keywords/fragmentation","display_name":"Fragmentation (computing)","score":0.596312403678894},{"id":"https://openalex.org/keywords/spectral-line","display_name":"Spectral line","score":0.5602876543998718},{"id":"https://openalex.org/keywords/mass-spectrum","display_name":"Mass spectrum","score":0.540040135383606},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5388370156288147},{"id":"https://openalex.org/keywords/dissociation","display_name":"Dissociation (chemistry)","score":0.5301017761230469},{"id":"https://openalex.org/keywords/mass-spectrometry","display_name":"Mass spectrometry","score":0.5014035701751709},{"id":"https://openalex.org/keywords/tandem","display_name":"Tandem","score":0.497602254152298},{"id":"https://openalex.org/keywords/ion","display_name":"Ion","score":0.4414999186992645},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32800307869911194},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.21614918112754822},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.19209569692611694},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.14546838402748108},{"id":"https://openalex.org/keywords/physical-chemistry","display_name":"Physical chemistry","score":0.08042252063751221}],"concepts":[{"id":"https://openalex.org/C31827203","wikidata":"https://www.wikidata.org/wiki/Q874296","display_name":"Tandem mass spectrometry","level":3,"score":0.7165480256080627},{"id":"https://openalex.org/C2777109674","wikidata":"https://www.wikidata.org/wiki/Q3710342","display_name":"Electron-transfer dissociation","level":4,"score":0.7134720087051392},{"id":"https://openalex.org/C191015642","wikidata":"https://www.wikidata.org/wiki/Q1132459","display_name":"Fragmentation (computing)","level":2,"score":0.596312403678894},{"id":"https://openalex.org/C4839761","wikidata":"https://www.wikidata.org/wiki/Q212111","display_name":"Spectral line","level":2,"score":0.5602876543998718},{"id":"https://openalex.org/C40325409","wikidata":"https://www.wikidata.org/wiki/Q2360668","display_name":"Mass spectrum","level":3,"score":0.540040135383606},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5388370156288147},{"id":"https://openalex.org/C102931765","wikidata":"https://www.wikidata.org/wiki/Q189673","display_name":"Dissociation (chemistry)","level":2,"score":0.5301017761230469},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.5014035701751709},{"id":"https://openalex.org/C2777814067","wikidata":"https://www.wikidata.org/wiki/Q1752317","display_name":"Tandem","level":2,"score":0.497602254152298},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.4414999186992645},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32800307869911194},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.21614918112754822},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.19209569692611694},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.14546838402748108},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.08042252063751221},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2014.6999144","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2014.6999144","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","display_name":"Affordable and clean energy","score":0.8199999928474426}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W166253295","https://openalex.org/W1966557933","https://openalex.org/W1978640976","https://openalex.org/W1981337935","https://openalex.org/W1986893074","https://openalex.org/W1994985444","https://openalex.org/W2011503307","https://openalex.org/W2021501656","https://openalex.org/W2023250395","https://openalex.org/W2025689383","https://openalex.org/W2031214076","https://openalex.org/W2057731158","https://openalex.org/W2068985738","https://openalex.org/W2080011781","https://openalex.org/W2085817013","https://openalex.org/W2105635160","https://openalex.org/W2137285891","https://openalex.org/W2139397135","https://openalex.org/W2327133606"],"related_works":["https://openalex.org/W2333051822","https://openalex.org/W2335176593","https://openalex.org/W2018265659","https://openalex.org/W1991329955","https://openalex.org/W2034476164","https://openalex.org/W2317609945","https://openalex.org/W1997777946","https://openalex.org/W1965372791","https://openalex.org/W2155742966","https://openalex.org/W2012682718"],"abstract_inverted_index":{"With":[0],"tandem":[1],"mass":[2],"spectrometry":[3],"(MS/MS),":[4],"spectra":[5,38,59,86,118],"can":[6],"be":[7],"generated":[8],"by":[9],"various":[10],"methods":[11],"including":[12],"collision-induced":[13],"dissociation":[14,18,22,27],"(CID),":[15],"higher-energy":[16],"collisional":[17],"(HCD),":[19],"electron":[20,25],"capture":[21],"(ECD)":[23],"and":[24,64,89,110],"transfer":[26],"(ETD).":[28],"At":[29],"the":[30,40,71,116,145],"same":[31,41],"time,":[32],"de":[33,79],"novo":[34,80],"sequencing":[35,81,136],"using":[36,55],"multiple":[37],"from":[39,60],"peptide":[42,135],"is":[43,54],"becoming":[44],"popular":[45],"in":[46,115,130],"proteomics":[47],"studies.":[48],"The":[49,123],"focus":[50],"of":[51,58,70,132,141],"this":[52],"work":[53],"a":[56,77],"pair":[57],"CID":[61],"(or":[62,66],"HCD)":[63],"ECD":[65],"ETD)":[67],"fragmentation":[68],"because":[69],"complementarity":[72],"between":[73],"them.":[74],"We":[75],"present":[76],"new":[78],"method":[82,96],"for":[83],"such":[84],"paired":[85,108],"named":[87,97],"NovoPair,":[88],"compare":[90],"its":[91],"performance":[92],"to":[93,106,119,149,152],"another":[94],"successful":[95],"pNovo+.":[98,153],"NovoPair":[99,127],"extends":[100],"our":[101],"previously":[102],"proposed":[103],"graph":[104],"model":[105],"suit":[107],"spectra,":[109],"considers":[111],"different":[112],"ion":[113],"types":[114],"two":[117],"extract":[120],"more":[121],"information.":[122],"results":[124],"show":[125],"that":[126],"outperforms":[128],"pNovo+":[129],"terms":[131],"full":[133],"length":[134],"accuracy":[137,146],"on":[138],"three":[139],"pairs":[140],"experimental":[142],"datasets,":[143],"with":[144],"increasing":[147],"up":[148],"13.6%":[150],"compared":[151]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}