{"id":"https://openalex.org/W2029118832","doi":"https://doi.org/10.1109/bibm.2013.6732678","title":"Mutual information mining for component law and development of new recipes for rheumatoid arthritis","display_name":"Mutual information mining for component law and development of new recipes for rheumatoid arthritis","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W2029118832","doi":"https://doi.org/10.1109/bibm.2013.6732678","mag":"2029118832"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2013.6732678","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2013.6732678","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003386296","display_name":"Qingzhong Qiu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210101306","display_name":"Integrated Chinese Medicine (China)","ror":"https://ror.org/01ahf6552","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210101306"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qingzhong Qiu","raw_affiliation_strings":["Guangdong Provincal Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China","Guangdong Provincal Hosp. of Integrated Traditional Chinese & Western Med., Foshan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Provincal Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China","institution_ids":["https://openalex.org/I4210101306"]},{"raw_affiliation_string":"Guangdong Provincal Hosp. of Integrated Traditional Chinese & Western Med., Foshan, China","institution_ids":["https://openalex.org/I4210101306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102887069","display_name":"Da Guo","orcid":"https://orcid.org/0000-0002-0688-5968"},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Da Guo","raw_affiliation_strings":["Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#"],"affiliations":[{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","institution_ids":["https://openalex.org/I117532281"]},{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068545245","display_name":"Jianke Pan","orcid":"https://orcid.org/0000-0002-4596-6111"},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianke Pan","raw_affiliation_strings":["Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#"],"affiliations":[{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","institution_ids":["https://openalex.org/I117532281"]},{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110632542","display_name":"Zhenwei Ma","orcid":null},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenwei Ma","raw_affiliation_strings":["Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#"],"affiliations":[{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","institution_ids":["https://openalex.org/I117532281"]},{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100609842","display_name":"Jun Liu","orcid":"https://orcid.org/0000-0001-6666-0982"},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Liu","raw_affiliation_strings":["Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#"],"affiliations":[{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","institution_ids":["https://openalex.org/I117532281"]},{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"last","author":{"id":null,"display_name":"Xuewei Cao","orcid":null},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuewei Cao","raw_affiliation_strings":["Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#"],"affiliations":[{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China","institution_ids":["https://openalex.org/I117532281"]},{"raw_affiliation_string":"Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China#TAB#","institution_ids":["https://openalex.org/I117532281"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5003386296"],"corresponding_institution_ids":["https://openalex.org/I4210101306"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1435139,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":null,"first_page":"222","last_page":"225"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12647","display_name":"Traditional Chinese Medicine Studies","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12647","display_name":"Traditional Chinese Medicine Studies","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research","score":0.991100013256073,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"Rheumatoid arthritis","score":0.8437117338180542},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"Traditional medicine","score":0.7476909756660461},{"id":"https://openalex.org/keywords/radix","display_name":"Radix (gastropod)","score":0.706442654132843},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7013316750526428},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"Traditional Chinese medicine","score":0.671867847442627},{"id":"https://openalex.org/keywords/medical-prescription","display_name":"Medical prescription","score":0.5539888739585876},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.21510136127471924},{"id":"https://openalex.org/keywords/alternative-medicine","display_name":"Alternative medicine","score":0.20636871457099915},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1589704155921936},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0773603618144989},{"id":"https://openalex.org/keywords/botany","display_name":"Botany","score":0.06960156559944153}],"concepts":[{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.8437117338180542},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.7476909756660461},{"id":"https://openalex.org/C2779091547","wikidata":"https://www.wikidata.org/wiki/Q287565","display_name":"Radix (gastropod)","level":2,"score":0.706442654132843},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7013316750526428},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.671867847442627},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.5539888739585876},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.21510136127471924},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.20636871457099915},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1589704155921936},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0773603618144989},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.06960156559944153},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2013.6732678","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2013.6732678","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1882935131","https://openalex.org/W1967127210","https://openalex.org/W1968920331","https://openalex.org/W1975737050","https://openalex.org/W2025441457","https://openalex.org/W2074963714","https://openalex.org/W2152090144","https://openalex.org/W6639464098"],"related_works":["https://openalex.org/W2412254868","https://openalex.org/W2390904641","https://openalex.org/W2361820086","https://openalex.org/W816882723","https://openalex.org/W2377485831","https://openalex.org/W1983892203","https://openalex.org/W2372843101","https://openalex.org/W2974060531","https://openalex.org/W3097515715","https://openalex.org/W2365559400"],"abstract_inverted_index":{"To":[0],"analyze":[1],"the":[2,34,38,68,83,142,150,155,181,187],"component":[3],"law":[4],"of":[5,45,70,85,91,124,189],"Chinese":[6,23,72,92,116],"medicines":[7,93,117],"for":[8,15,26,75,111,118,145],"rheumatoid":[9,16,27,76,112,119,146,190],"arthritis,":[10,77],"and":[11,31,36,47,61,82,88,101,107,126,130,134,138,153,177],"develop":[12],"new":[13,48,109],"prescriptions":[14,49],"arthritis":[17,28,113,120],"through":[18],"mutual":[19,55],"Information":[20],"mining":[21],"methods.":[22],"medicine":[24,73],"recipes":[25,74,110],"were":[29,50,105,114,121],"collected":[30],"recorded":[32],"in":[33,95,186],"database,":[35],"then":[37],"correlation":[39],"coefficient":[40],"between":[41],"herbs,":[42],"core":[43,103],"combinations":[44,104],"herbs":[46],"analyzed":[51],"by":[52],"using":[53],"modified":[54],"information,":[56],"complex":[57],"system":[58],"entropy":[59],"cluster":[60],"unsupervised":[62],"hierarchical":[63],"clustering,":[64],"respectively.":[65],"Based":[66],"on":[67],"analysis":[69],"63":[71],"30":[78],"drugs":[79,184],"with":[80],"high-frequency":[81],"distribution":[84],"Four":[86],"Qi":[87],"Five":[89],"Flavors":[90],"occurrence":[94],"these":[96],"recipes,34":[97],"frequently-used":[98],"herb":[99],"pairs":[100],"9":[102],"founded,":[106],"3":[108],"developed.":[115],"mainly":[122],"consist":[123],"blood-activating":[125],"stasis-dispelling":[127],"edicinal,":[128],"wind-dampnessdispelling":[129],"heatclearing":[131],"medicinal,":[132,136],"heat-clearing":[133],"detoxicating":[135],"tonifying":[137],"replenishing":[139],"medicinal.":[140],"So,":[141],"therapeutic":[143],"principle":[144],"arthritisis":[147],"to":[148],"reinforce":[149],"healthy":[151],"qi":[152],"eliminate":[154],"pathogenic":[156],"factors.":[157],"Radix":[158,163,175,178],"Gentianae":[159],"Macrophyllae,":[160],"Rhizoma":[161],"Chuanxiong,":[162],"Glycyrrhizae,Radix":[164],"Angelicae":[165,169],"Pubescentis,Radix":[166],"Paeoniae":[167],"Alba,Radix":[168],"Sinensis,Radix":[170],"Achyranthis":[171],"Bidentatae,Ramulus":[172],"Cinnamomi,Rhizoma":[173],"Et":[174],"Notopterygii":[176],"Astragali":[179],"are":[180],"main":[182],"herbal":[183],"used":[185],"treatment":[188],"arthritis.":[191]},"counts_by_year":[],"updated_date":"2026-04-17T18:11:37.981687","created_date":"2025-10-10T00:00:00"}