{"id":"https://openalex.org/W4391381639","doi":"https://doi.org/10.1109/wsc60868.2023.10407665","title":"Modelling and Simulation of Genomic Sequencing Platform Operations","display_name":"Modelling and Simulation of Genomic Sequencing Platform Operations","publication_year":2023,"publication_date":"2023-12-10","ids":{"openalex":"https://openalex.org/W4391381639","doi":"https://doi.org/10.1109/wsc60868.2023.10407665"},"language":"en","primary_location":{"id":"doi:10.1109/wsc60868.2023.10407665","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/wsc60868.2023.10407665","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 Winter Simulation Conference (WSC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012370440","display_name":"Jules Le Lay","orcid":"https://orcid.org/0000-0003-4186-5716"},"institutions":[{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"funder","lineage":["https://openalex.org/I4210105738"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jules Le Lay","raw_affiliation_strings":["Centre Leon Berard,Direction of Clinical Research and Innovation,Lyon,France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre Leon Berard,Direction of Clinical Research and Innovation,Lyon,France","institution_ids":["https://openalex.org/I4210105738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017135008","display_name":"Lionel Perrier","orcid":"https://orcid.org/0000-0003-4487-8723"},"institutions":[{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"funder","lineage":["https://openalex.org/I4210105738"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lionel Perrier","raw_affiliation_strings":["Centre Leon Berard,Direction of Clinical Research and Innovation,Lyon,France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre Leon Berard,Direction of Clinical Research and Innovation,Lyon,France","institution_ids":["https://openalex.org/I4210105738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055669214","display_name":"Vincent Augusto","orcid":"https://orcid.org/0000-0002-5063-0831"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I3019848993","display_name":"Mines Saint-\u00c9tienne","ror":"https://ror.org/05a1dws80","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vincent Augusto","raw_affiliation_strings":["Mines Saint-Etienne Univ Clermont Auvergne INP Clermont Auvergne CNRS,UMR 6158 LIMOS,Saint-Etienne,France,F - 42023"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mines Saint-Etienne Univ Clermont Auvergne INP Clermont Auvergne CNRS,UMR 6158 LIMOS,Saint-Etienne,France,F - 42023","institution_ids":["https://openalex.org/I3019848993","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026560143","display_name":"Xavier Boucher","orcid":"https://orcid.org/0000-0002-0869-4153"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I3019848993","display_name":"Mines Saint-\u00c9tienne","ror":"https://ror.org/05a1dws80","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Xavier Boucher","raw_affiliation_strings":["Mines Saint-Etienne Univ Clermont Auvergne INP Clermont Auvergne CNRS,UMR 6158 LIMOS,Saint-Etienne,France,F - 42023"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mines Saint-Etienne Univ Clermont Auvergne INP Clermont Auvergne CNRS,UMR 6158 LIMOS,Saint-Etienne,France,F - 42023","institution_ids":["https://openalex.org/I3019848993","https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044117021","display_name":"Xiaolan Xie","orcid":"https://orcid.org/0000-0002-6579-1523"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I3019848993","display_name":"Mines Saint-\u00c9tienne","ror":"https://ror.org/05a1dws80","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Xiaolan Xie","raw_affiliation_strings":["Mines Saint-Etienne Univ Clermont Auvergne INP Clermont Auvergne CNRS,UMR 6158 LIMOS,Saint-Etienne,France,F - 42023"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mines Saint-Etienne Univ Clermont Auvergne INP Clermont Auvergne CNRS,UMR 6158 LIMOS,Saint-Etienne,France,F - 42023","institution_ids":["https://openalex.org/I3019848993","https://openalex.org/I1294671590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28665367,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"71","issue":null,"first_page":"1160","last_page":"1171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9581000208854675,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/software-deployment","display_name":"Software deployment","score":0.7708308696746826},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5762632489204407},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.5439034700393677},{"id":"https://openalex.org/keywords/throughput","display_name":"Throughput","score":0.5063210725784302},{"id":"https://openalex.org/keywords/field","display_name":"Field (mathematics)","score":0.4816107451915741},{"id":"https://openalex.org/keywords/state","display_name":"State (computer science)","score":0.458228200674057},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"Decision support system","score":0.4239214360713959},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.33169621229171753},{"id":"https://openalex.org/keywords/systems-engineering","display_name":"Systems engineering","score":0.32564789056777954},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.3214392066001892},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.3044971227645874},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.18242678046226501},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.10384771227836609},{"id":"https://openalex.org/keywords/wireless","display_name":"Wireless","score":0.09371161460876465}],"concepts":[{"id":"https://openalex.org/C105339364","wikidata":"https://www.wikidata.org/wiki/Q2297740","display_name":"Software deployment","level":2,"score":0.7708308696746826},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5762632489204407},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.5439034700393677},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.5063210725784302},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.4816107451915741},{"id":"https://openalex.org/C48103436","wikidata":"https://www.wikidata.org/wiki/Q599031","display_name":"State (computer science)","level":2,"score":0.458228200674057},{"id":"https://openalex.org/C107327155","wikidata":"https://www.wikidata.org/wiki/Q330268","display_name":"Decision support system","level":2,"score":0.4239214360713959},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.33169621229171753},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.32564789056777954},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.3214392066001892},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3044971227645874},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.18242678046226501},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.10384771227836609},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.09371161460876465},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/wsc60868.2023.10407665","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/wsc60868.2023.10407665","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 Winter Simulation Conference (WSC)","raw_type":"proceedings-article"},{"id":"pmh:oai:HAL:hal-04472221v1","is_oa":false,"landing_page_url":"https://hal.science/hal-04472221","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2023 Winter Simulation Conference (WSC), Dec 2023, San Antonio, United States. pp.1160-1171, ⟨10.1109/WSC60868.2023.10407665⟩","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1978340236","https://openalex.org/W2037809152","https://openalex.org/W2062749309","https://openalex.org/W2096656774","https://openalex.org/W2164768649","https://openalex.org/W2168909179","https://openalex.org/W2565508359","https://openalex.org/W2611574484","https://openalex.org/W2617577454","https://openalex.org/W2792381148","https://openalex.org/W2888616775","https://openalex.org/W2968056273","https://openalex.org/W3013595319","https://openalex.org/W3096103868","https://openalex.org/W3105669972","https://openalex.org/W3138612854","https://openalex.org/W3172315055","https://openalex.org/W3212464243","https://openalex.org/W3217316753","https://openalex.org/W4200418089","https://openalex.org/W4220809095","https://openalex.org/W4220980823","https://openalex.org/W4281845612","https://openalex.org/W4304080447","https://openalex.org/W4310887545","https://openalex.org/W6601141590","https://openalex.org/W6678791002","https://openalex.org/W6845475545"],"related_works":["https://openalex.org/W2770234245","https://openalex.org/W96612179","https://openalex.org/W4229499248","https://openalex.org/W2566006169","https://openalex.org/W1567818861","https://openalex.org/W2987774938","https://openalex.org/W4256492088","https://openalex.org/W632915154","https://openalex.org/W2055733372","https://openalex.org/W3022067003"],"abstract_inverted_index":{"This":[0],"paper":[1],"focuses":[2],"on":[3],"the":[4,13,41,58,64,73,79,84,87,126],"healthcare":[5],"application":[6,112],"field":[7],"of":[8,15,20,44,75,86,92,114],"Genomic":[9],"Sequencing":[10],"and":[11,18,133],"addresses":[12],"challenge":[14],"efficient":[16],"organization":[17],"ramp-up":[19,108],"sequencing":[21,24,95,117],"platforms.":[22],"High-throughput":[23],"platforms":[25,77],"are":[26,122],"currently":[27],"in":[28,33,67],"an":[29,111],"industrial":[30],"prototyping":[31],"phase":[32],"France":[34],"for":[35,110],"large":[36],"national":[37,80],"deployment":[38,74],"afterwards.":[39],"In":[40],"current":[42],"state":[43,85],"our":[45],"knowledge,":[46],"there":[47],"is":[48,97],"no":[49],"scientifically":[50],"established":[51],"generic":[52,131],"model":[53,91,132],"nor":[54],"decision-making":[55,103],"support":[56,104],"at":[57,78],"operational":[59],"level":[60],"which":[61],"could":[62],"guide":[63],"medical":[65],"authorities":[66],"designing":[68],"organizational":[69],"rules,":[70],"then":[71,99],"managing":[72],"such":[76],"level.":[81],"After":[82],"analyzing":[83],"art,":[88],"a":[89,93,102,107,115,130],"simulation":[90],"genome":[94],"platform":[96],"presented,":[98],"used":[100],"as":[101],"to":[105,128],"manage":[106],"situation":[109],"case":[113],"French":[116],"platform.":[118],"These":[119],"first":[120],"results":[121],"discussed,":[123],"together":[124],"with":[125],"perspective":[127],"develop":[129],"decision-aid":[134],"approach.":[135]},"counts_by_year":[],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}