{"id":"https://openalex.org/W4401880726","doi":"https://doi.org/10.1109/vlsitechnologyandcir46783.2024.10631479","title":"A Subcellular-Resolution Multimodal CMOS Biosensor Array with 16K Ion-Selective Pixels for Real-Time Monitoring Potassium Dynamics","display_name":"A Subcellular-Resolution Multimodal CMOS Biosensor Array with 16K Ion-Selective Pixels for Real-Time Monitoring Potassium Dynamics","publication_year":2024,"publication_date":"2024-06-16","ids":{"openalex":"https://openalex.org/W4401880726","doi":"https://doi.org/10.1109/vlsitechnologyandcir46783.2024.10631479"},"language":"en","primary_location":{"id":"doi:10.1109/vlsitechnologyandcir46783.2024.10631479","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/vlsitechnologyandcir46783.2024.10631479","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009087402","display_name":"Hangxing Liu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hangxing Liu","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071763873","display_name":"Fuze Jiang","orcid":"https://orcid.org/0000-0001-5685-170X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fuze Jiang","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100656293","display_name":"Ying Kong","orcid":"https://orcid.org/0000-0002-0183-247X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ying Kong","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100405096","display_name":"Dongwon Lee","orcid":"https://orcid.org/0000-0003-3035-6342"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dongwon Lee","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050623467","display_name":"Yuguo Sheng","orcid":"https://orcid.org/0000-0003-1763-3624"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuguo Sheng","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101829658","display_name":"Adam Wang","orcid":"https://orcid.org/0000-0003-3492-1943"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adam Wang","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053768392","display_name":"Zhi-Kai Huang","orcid":"https://orcid.org/0000-0003-1252-2001"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhikai Huang","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039330599","display_name":"Marco Saif","orcid":"https://orcid.org/0000-0002-5591-610X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco Saif","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054925904","display_name":"Thomas Burger","orcid":"https://orcid.org/0000-0002-1399-5444"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas Burger","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100759077","display_name":"Jing Wang","orcid":"https://orcid.org/0000-0003-2078-137X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Wang","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100646268","display_name":"Hua Wang","orcid":"https://orcid.org/0000-0003-4952-5505"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hua Wang","raw_affiliation_strings":["ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Z&#x00FC;rich,Z&#x00FC;rich,Switzerland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":11,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13025738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11992","display_name":"CCD and CMOS Imaging Sensors","score":0.9627000093460083,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.5733331441879272},{"id":"https://openalex.org/keywords/cmos","display_name":"CMOS","score":0.5504522919654846},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.5281481742858887},{"id":"https://openalex.org/keywords/resolution","display_name":"Resolution (logic)","score":0.521552562713623},{"id":"https://openalex.org/keywords/image-resolution","display_name":"Image resolution","score":0.5027279853820801},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4922095835208893},{"id":"https://openalex.org/keywords/potassium","display_name":"Potassium","score":0.4751063287258148},{"id":"https://openalex.org/keywords/computer-hardware","display_name":"Computer hardware","score":0.342929482460022},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.2402586042881012},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.2190965712070465},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.21362298727035522},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16921848058700562}],"concepts":[{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.5733331441879272},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.5504522919654846},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.5281481742858887},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.521552562713623},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.5027279853820801},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4922095835208893},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.4751063287258148},{"id":"https://openalex.org/C9390403","wikidata":"https://www.wikidata.org/wiki/Q3966","display_name":"Computer hardware","level":1,"score":0.342929482460022},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.2402586042881012},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2190965712070465},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.21362298727035522},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16921848058700562},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/vlsitechnologyandcir46783.2024.10631479","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/vlsitechnologyandcir46783.2024.10631479","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6000000238418579,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2046430340","https://openalex.org/W2383021773","https://openalex.org/W2322026400","https://openalex.org/W4206515393","https://openalex.org/W1990396141","https://openalex.org/W2044092692","https://openalex.org/W2614621130","https://openalex.org/W2547665164","https://openalex.org/W3103111272","https://openalex.org/W4289655544"],"abstract_inverted_index":{"Ion":[0],"sensing":[1],"offers":[2],"an":[3],"efficient":[4],"tool":[5],"for":[6,16,31,66],"deep":[7],"understanding":[8],"of":[9,62],"ion":[10],"channel-related":[11],"diseases":[12],"such":[13],"as":[14],"K+":[15],"hyperproliferative":[17],"tumors":[18],"[1].":[19],"In":[20],"this":[21],"work,":[22],"we":[23],"present":[24],"the":[25],"first":[26],"biocompatible":[27],"ion-selective":[28,69],"bioimaging":[29],"array":[30,60],"cellular":[32],"characterization":[33],"and":[34,72],"modulation,":[35],"fully":[36],"integrated":[37],"in":[38],"a":[39,47],"CMOS":[40,57],"chip":[41],"with":[42],"16K":[43],"multi-modal":[44],"pixels":[45],"at":[46],"subcellular":[48],"<tex":[49],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[50],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">$5.4-\\mu":[51],"\\mathrm{m}$</tex>":[52],"-pitch":[53],"resolution.":[54],"This":[55],"multimodal":[56],"cell":[58,67],"interfacing":[59],"consists":[61],"in-pixel":[63],"biosensing/actuation":[64],"circuits":[65],"localization,":[68],"concentration":[70],"monitoring,":[71],"plasma":[73],"membrane":[74],"stimulation.":[75]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}