{"id":"https://openalex.org/W4401881163","doi":"https://doi.org/10.1109/vlsitechnologyandcir46783.2024.10631420","title":"Highly Sensitive Multimodal CMOS Antifouling Sensor Array with Multi-Use Electrodes for Single-Cell-Level Profiling of Biophysical and Biochemical Parameters","display_name":"Highly Sensitive Multimodal CMOS Antifouling Sensor Array with Multi-Use Electrodes for Single-Cell-Level Profiling of Biophysical and Biochemical Parameters","publication_year":2024,"publication_date":"2024-06-16","ids":{"openalex":"https://openalex.org/W4401881163","doi":"https://doi.org/10.1109/vlsitechnologyandcir46783.2024.10631420"},"language":"en","primary_location":{"id":"doi:10.1109/vlsitechnologyandcir46783.2024.10631420","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/vlsitechnologyandcir46783.2024.10631420","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009087402","display_name":"Hangxing Liu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hangxing Liu","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103158427","display_name":"Fuze Jiang","orcid":"https://orcid.org/0000-0003-2581-5065"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fuze Jiang","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101829658","display_name":"Adam Wang","orcid":"https://orcid.org/0000-0003-3492-1943"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adam Wang","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053768392","display_name":"Zhi-Kai Huang","orcid":"https://orcid.org/0000-0003-1252-2001"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhikai Huang","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100656293","display_name":"Ying Kong","orcid":"https://orcid.org/0000-0002-0183-247X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ying Kong","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039330599","display_name":"Marco Saif","orcid":"https://orcid.org/0000-0002-5591-610X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco Saif","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100405096","display_name":"Dongwon Lee","orcid":"https://orcid.org/0000-0003-3035-6342"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dongwon Lee","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054925904","display_name":"Thomas Burger","orcid":"https://orcid.org/0000-0002-1399-5444"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas Burger","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100759077","display_name":"Jing Wang","orcid":"https://orcid.org/0000-0003-2078-137X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Wang","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100646268","display_name":"Hua Wang","orcid":"https://orcid.org/0000-0003-4952-5505"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hua Wang","raw_affiliation_strings":["ETH Zürich,Zürich,Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zürich,Zürich,Switzerland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":10,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2556,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.4905838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9805999994277954,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9805999994277954,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9308000206947327,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/profiling","display_name":"Profiling (computer programming)","score":0.8035996556282043},{"id":"https://openalex.org/keywords/cmos","display_name":"CMOS","score":0.6481153964996338},{"id":"https://openalex.org/keywords/biofouling","display_name":"Biofouling","score":0.6357892751693726},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.46889060735702515},{"id":"https://openalex.org/keywords/single-cell-analysis","display_name":"Single-cell analysis","score":0.4591500163078308},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44080352783203125},{"id":"https://openalex.org/keywords/electrode-array","display_name":"Electrode array","score":0.42189860343933105},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.4143243432044983},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.4127499759197235},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.354434609413147},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.2899128794670105},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.28159213066101074},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.19768619537353516}],"concepts":[{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.8035996556282043},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.6481153964996338},{"id":"https://openalex.org/C6047279","wikidata":"https://www.wikidata.org/wiki/Q1439821","display_name":"Biofouling","level":3,"score":0.6357892751693726},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.46889060735702515},{"id":"https://openalex.org/C2776950831","wikidata":"https://www.wikidata.org/wiki/Q15635432","display_name":"Single-cell analysis","level":3,"score":0.4591500163078308},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44080352783203125},{"id":"https://openalex.org/C97562148","wikidata":"https://www.wikidata.org/wiki/Q5357989","display_name":"Electrode array","level":3,"score":0.42189860343933105},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.4143243432044983},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4127499759197235},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.354434609413147},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2899128794670105},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.28159213066101074},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.19768619537353516},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/vlsitechnologyandcir46783.2024.10631420","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/vlsitechnologyandcir46783.2024.10631420","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.6299999952316284,"display_name":"Affordable and clean energy"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W4230170236"],"related_works":["https://openalex.org/W4234458579","https://openalex.org/W4286615825","https://openalex.org/W2359695434","https://openalex.org/W2357529910","https://openalex.org/W2351135390","https://openalex.org/W2946240729","https://openalex.org/W3023719170","https://openalex.org/W4377564747","https://openalex.org/W4200066687","https://openalex.org/W2460059583"],"abstract_inverted_index":{"Monitoring":[0],"cell":[1,37],"bio-responses":[2],"in":[3,36],"organ-on-chip":[4],"platforms":[5],"is":[6],"crucial":[7],"for":[8,25],"accurately":[9],"predicting":[10],"organ":[11],"reactions":[12],"to":[13],"medications":[14],"over":[15],"time.":[16],"This":[17],"work":[18],"presents":[19],"an":[20],"antifouling":[21],"CMOS":[22],"sensor":[23],"platform":[24],"in-vitro,":[26],"single-cell-level":[27],"and":[28,33,39,66,69,79],"multimodal":[29],"sensing":[30,45,59],"of":[31],"biophysical":[32],"biochemical":[34],"parameters":[35],"proliferation":[38],"inflammation.":[40],"The":[41],"chip":[42],"features":[43],"4,096":[44],"pixels":[46],"at":[47],"$45-\\mu":[50],"\\mathrm{m}$":[51],"spatial":[52],"resolution.":[53],"Each":[54],"pixel":[55],"node":[56],"offers":[57],"four":[58],"modalities":[60],"(impedance":[61],"tomography,":[62],"electrochemistry,":[63],"shadow":[64],"imaging,":[65],"pH":[67],"sensing)":[68],"three":[70],"actuation":[71],"functions":[72],"(dielectrophoresis":[73],"(DEP)":[74],"as":[75,77],"well":[76],"voltage":[78],"current":[80],"stimulations).":[81]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}