{"id":"https://openalex.org/W4413010751","doi":"https://doi.org/10.1109/tvcg.2025.3596385","title":"Uncertainty Visualization for Biomolecular Structures: An Empirical Evaluation","display_name":"Uncertainty Visualization for Biomolecular Structures: An Empirical Evaluation","publication_year":2025,"publication_date":"2025-08-06","ids":{"openalex":"https://openalex.org/W4413010751","doi":"https://doi.org/10.1109/tvcg.2025.3596385","pmid":"https://pubmed.ncbi.nlm.nih.gov/40768449"},"language":"en","primary_location":{"id":"doi:10.1109/tvcg.2025.3596385","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tvcg.2025.3596385","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1109/tvcg.2025.3596385","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092109868","display_name":"Anna Sterzik","orcid":"https://orcid.org/0000-0002-0544-5397"},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Anna Sterzik","raw_affiliation_strings":["University of Jena, Jena, Germany","University of Jena, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0544-5397","affiliations":[{"raw_affiliation_string":"University of Jena, Jena, Germany","institution_ids":[]},{"raw_affiliation_string":"University of Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003476748","display_name":"Michael Krone","orcid":"https://orcid.org/0000-0002-1445-7568"},"institutions":[{"id":"https://openalex.org/I31582689","display_name":"Stuttgart Technical University of Applied Sciences","ror":"https://ror.org/039gdg280","country_code":"DE","type":"education","lineage":["https://openalex.org/I31582689"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Krone","raw_affiliation_strings":["Stuttgart University of Applied Sciences (HFT), Stuttgart, Germany","Stuttgart University of Applied Sciences (HFT), Germany"],"raw_orcid":"https://orcid.org/0000-0002-1445-7568","affiliations":[{"raw_affiliation_string":"Stuttgart University of Applied Sciences (HFT), Stuttgart, Germany","institution_ids":["https://openalex.org/I31582689"]},{"raw_affiliation_string":"Stuttgart University of Applied Sciences (HFT), Germany","institution_ids":["https://openalex.org/I31582689"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012693590","display_name":"Daniel Baum","orcid":"https://orcid.org/0000-0003-1550-7245"},"institutions":[{"id":"https://openalex.org/I195893171","display_name":"Zuse Institute Berlin","ror":"https://ror.org/02eva5865","country_code":"DE","type":"facility","lineage":["https://openalex.org/I195893171"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniel Baum","raw_affiliation_strings":["Zuse Institute Berlin, Berlin, Germany","Zuse Institute Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1550-7245","affiliations":[{"raw_affiliation_string":"Zuse Institute Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I195893171"]},{"raw_affiliation_string":"Zuse Institute Berlin, Germany","institution_ids":["https://openalex.org/I195893171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020400873","display_name":"Douglas W. Cunningham","orcid":"https://orcid.org/0000-0003-1419-2552"},"institutions":[{"id":"https://openalex.org/I4210146756","display_name":"Brandenburg University of Applied Sciences","ror":"https://ror.org/04qj3gf68","country_code":"DE","type":"education","lineage":["https://openalex.org/I4210146756"]},{"id":"https://openalex.org/I51783024","display_name":"Brandenburg University of Technology Cottbus-Senftenberg","ror":"https://ror.org/02wxx3e24","country_code":"DE","type":"education","lineage":["https://openalex.org/I51783024"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Douglas W. Cunningham","raw_affiliation_strings":["Brandenburg University of Technology, Cottbus, Germany","Brandenburg University of Technology, Germany"],"raw_orcid":"https://orcid.org/0000-0003-1419-2552","affiliations":[{"raw_affiliation_string":"Brandenburg University of Technology, Cottbus, Germany","institution_ids":["https://openalex.org/I51783024"]},{"raw_affiliation_string":"Brandenburg University of Technology, Germany","institution_ids":["https://openalex.org/I4210146756","https://openalex.org/I51783024"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005017697","display_name":"Kai Lawonn","orcid":"https://orcid.org/0000-0002-1511-4022"},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kai Lawonn","raw_affiliation_strings":["University of Jena, Jena, Germany","University of Jena, Germany"],"raw_orcid":"https://orcid.org/0000-0002-1511-4022","affiliations":[{"raw_affiliation_string":"University of Jena, Jena, Germany","institution_ids":[]},{"raw_affiliation_string":"University of Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5092109868"],"corresponding_institution_ids":["https://openalex.org/I76198965"],"apc_list":null,"apc_paid":null,"fwci":2.2665,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.89205563,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"31","issue":"12","first_page":"10296","last_page":"10310"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10799","display_name":"Data Visualization and Analytics","score":0.5561000108718872,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10799","display_name":"Data Visualization and Analytics","score":0.5561000108718872,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.79552161693573},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7426618337631226},{"id":"https://openalex.org/keywords/data-visualization","display_name":"Data visualization","score":0.6080823540687561},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.44276896119117737},{"id":"https://openalex.org/keywords/information-visualization","display_name":"Information visualization","score":0.435271292924881},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.2847142815589905}],"concepts":[{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.79552161693573},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7426618337631226},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.6080823540687561},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.44276896119117737},{"id":"https://openalex.org/C185578843","wikidata":"https://www.wikidata.org/wiki/Q10609775","display_name":"Information visualization","level":3,"score":0.435271292924881},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2847142815589905}],"mesh":[{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/tvcg.2025.3596385","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tvcg.2025.3596385","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},{"id":"pmid:40768449","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40768449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on visualization and computer graphics","raw_type":null}],"best_oa_location":{"id":"doi:10.1109/tvcg.2025.3596385","is_oa":true,"landing_page_url":"https://doi.org/10.1109/tvcg.2025.3596385","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8231461557","display_name":null,"funder_award_id":"437702916","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1489700509","https://openalex.org/W1546610148","https://openalex.org/W1601042374","https://openalex.org/W1830509574","https://openalex.org/W1892242977","https://openalex.org/W1931416451","https://openalex.org/W1972641242","https://openalex.org/W1975575027","https://openalex.org/W1978765861","https://openalex.org/W1985848994","https://openalex.org/W1994637805","https://openalex.org/W2002195659","https://openalex.org/W2006192061","https://openalex.org/W2012117816","https://openalex.org/W2027786195","https://openalex.org/W2029667189","https://openalex.org/W2039302387","https://openalex.org/W2043359500","https://openalex.org/W2044988964","https://openalex.org/W2048822589","https://openalex.org/W2065782985","https://openalex.org/W2089888367","https://openalex.org/W2094468738","https://openalex.org/W2097173901","https://openalex.org/W2100782177","https://openalex.org/W2101481219","https://openalex.org/W2103982525","https://openalex.org/W2104312285","https://openalex.org/W2109617680","https://openalex.org/W2109911343","https://openalex.org/W2114084204","https://openalex.org/W2116643156","https://openalex.org/W2124879102","https://openalex.org/W2134468204","https://openalex.org/W2135412641","https://openalex.org/W2140275771","https://openalex.org/W2153367278","https://openalex.org/W2169113748","https://openalex.org/W2170402458","https://openalex.org/W2292312835","https://openalex.org/W2343385447","https://openalex.org/W2373591197","https://openalex.org/W2416272719","https://openalex.org/W2549327495","https://openalex.org/W2559034548","https://openalex.org/W2608970480","https://openalex.org/W2769556621","https://openalex.org/W2792985086","https://openalex.org/W2795752238","https://openalex.org/W2796347334","https://openalex.org/W2801136517","https://openalex.org/W2805556045","https://openalex.org/W2891628559","https://openalex.org/W2894111542","https://openalex.org/W2972342264","https://openalex.org/W3036908639","https://openalex.org/W3083406432","https://openalex.org/W3141795233","https://openalex.org/W3168379310","https://openalex.org/W3190622317","https://openalex.org/W4213165903","https://openalex.org/W4236582369","https://openalex.org/W4376126459","https://openalex.org/W4379744940","https://openalex.org/W4387885616","https://openalex.org/W4387885673","https://openalex.org/W4410790099"],"related_works":["https://openalex.org/W2105200106","https://openalex.org/W1574055964","https://openalex.org/W2295030662","https://openalex.org/W4225274103","https://openalex.org/W2923661510","https://openalex.org/W1938514595","https://openalex.org/W2579659702","https://openalex.org/W2147893003","https://openalex.org/W2520625499","https://openalex.org/W4312790984"],"abstract_inverted_index":{"Uncertainty":[0,51],"is":[1,33,46,54,177],"an":[2],"intrinsic":[3],"property":[4],"of":[5,10,26,142,174,186,201],"almost":[6],"all":[7],"data,":[8,43],"regardless":[9],"the":[11,22,88,131,138,143,147,157,163,172,175,184,191,199,202],"data":[12],"being":[13],"measured,":[14],"simulated,":[15],"or":[16],"generated.":[17],"It":[18],"can":[19],"significantly":[20],"influence":[21],"results":[23],"and":[24,38,74,93,105,111,123,140,150,170,207],"reliability":[25],"subsequent":[27],"analysis":[28],"steps.":[29],"Clearly":[30],"communicating":[31],"uncertainties":[32],"crucial":[34],"for":[35,58,78,146,153,204,211],"informed":[36],"decision-making":[37],"understanding,":[39],"especially":[40],"in":[41,82,113],"biomolecular":[42,83],"where":[44],"uncertainty":[45,64,81,169,188,206],"often":[47],"difficult":[48],"to":[49,136],"infer.":[50],"visualization":[52,65,76],"(UV)":[53,66],"a":[55,114],"powerful":[56],"tool":[57],"this":[59],"purpose.":[60],"However,":[61],"previously":[62],"proposed":[63],"methods":[67,77,89,145],"lack":[68],"sufficient":[69],"empirical":[70],"evaluation.":[71],"We":[72,85,107,181],"collected":[73],"categorized":[75],"portraying":[79],"positional":[80],"structures.":[84],"then":[86],"organized":[87],"into":[90],"metaphorical":[91],"groups":[92],"extracted":[94],"nine":[95],"representatives:":[96],"color,":[97],"clouds,":[98],"ensemble,":[99],"hulls,":[100],"sausages,":[101],"contours,":[102],"texture,":[103],"waves,":[104],"noise.":[106],"assessed":[108,183],"their":[109],"strengths":[110],"weaknesses":[112],"twofold":[115],"approach:":[116],"expert":[117,132],"assessments":[118],"with":[119,168],"six":[120],"domain":[121,149],"experts":[122],"three":[124],"perceptual":[125,158],"evaluations":[126],"involving":[127],"1,756":[128],"participants.":[129],"Through":[130,156],"assessments,":[133],"we":[134,160,197],"aimed":[135],"highlight":[137],"advantages":[139],"limitations":[141],"individual":[144],"application":[148],"discussed":[151],"areas":[152,210],"necessary":[154],"improvements.":[155],"evaluation,":[159],"investigated":[161],"whether":[162,171],"visualizations":[164],"are":[165],"intuitively":[166],"associated":[167],"directionality":[173],"mapping":[176],"perceived":[178],"as":[179],"intended.":[180],"also":[182],"accuracy":[185],"inferring":[187],"values":[189],"from":[190],"visualizations.":[192],"Based":[193],"on":[194],"our":[195],"results,":[196],"judged":[198],"appropriateness":[200],"metaphors":[203],"encoding":[205],"suggest":[208],"further":[209],"improvement.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2025-11-07T23:20:04.922697","created_date":"2025-10-10T00:00:00"}
