{"id":"https://openalex.org/W3093304249","doi":"https://doi.org/10.1109/tvcg.2021.3137174","title":"A Predictive Visual Analytics System for Studying Neurodegenerative Disease Based on DTI Fiber Tracts","display_name":"A Predictive Visual Analytics System for Studying Neurodegenerative Disease Based on DTI Fiber Tracts","publication_year":2021,"publication_date":"2021-12-29","ids":{"openalex":"https://openalex.org/W3093304249","doi":"https://doi.org/10.1109/tvcg.2021.3137174","mag":"3093304249","pmid":"https://pubmed.ncbi.nlm.nih.gov/34965212"},"language":"en","primary_location":{"id":"doi:10.1109/tvcg.2021.3137174","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tvcg.2021.3137174","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081007489","display_name":"Chaoqing Xu","orcid":"https://orcid.org/0000-0003-0955-5611"},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chaoqing Xu","raw_affiliation_strings":["College of Computer Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China"],"raw_orcid":"https://orcid.org/0000-0003-0955-5611","affiliations":[{"raw_affiliation_string":"College of Computer Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083143514","display_name":"Tyson Neuroth","orcid":"https://orcid.org/0000-0002-5866-5959"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyson Neuroth","raw_affiliation_strings":["University of California, Davis, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5866-5959","affiliations":[{"raw_affiliation_string":"University of California, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074006931","display_name":"Takanori Fujiwara","orcid":"https://orcid.org/0000-0002-6382-2752"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Takanori Fujiwara","raw_affiliation_strings":["University of California, Davis, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-6382-2752","affiliations":[{"raw_affiliation_string":"University of California, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001531117","display_name":"Ronghua Liang","orcid":"https://orcid.org/0000-0003-2077-9608"},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ronghua Liang","raw_affiliation_strings":["College of Computer Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China"],"raw_orcid":"https://orcid.org/0000-0003-2077-9608","affiliations":[{"raw_affiliation_string":"College of Computer Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037161857","display_name":"Kwan\u2010Liu Ma","orcid":"https://orcid.org/0000-0001-8086-0366"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kwan-Liu Ma","raw_affiliation_strings":["University of California, Davis, CA, USA"],"raw_orcid":"https://orcid.org/0000-0001-8086-0366","affiliations":[{"raw_affiliation_string":"University of California, Davis, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5081007489"],"corresponding_institution_ids":["https://openalex.org/I55712492"],"apc_list":null,"apc_paid":null,"fwci":0.6963,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.68309028,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"29","issue":"4","first_page":"2020","last_page":"2035"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9873999953269958,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9871000051498413,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.7783252000808716},{"id":"https://openalex.org/keywords/visual-analytics","display_name":"Visual analytics","score":0.7441733479499817},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7382138967514038},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.5814433097839355},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5088615417480469},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.500194787979126},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.487344354391098},{"id":"https://openalex.org/keywords/data-visualization","display_name":"Data visualization","score":0.47002434730529785},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.42246532440185547},{"id":"https://openalex.org/keywords/human\u2013computer-interaction","display_name":"Human\u2013computer interaction","score":0.3752010762691498},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3562629222869873},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.22589871287345886},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16546201705932617}],"concepts":[{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.7783252000808716},{"id":"https://openalex.org/C59732488","wikidata":"https://www.wikidata.org/wiki/Q2528440","display_name":"Visual analytics","level":3,"score":0.7441733479499817},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7382138967514038},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.5814433097839355},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5088615417480469},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.500194787979126},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.487344354391098},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.47002434730529785},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.42246532440185547},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.3752010762691498},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3562629222869873},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.22589871287345886},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16546201705932617},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/tvcg.2021.3137174","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tvcg.2021.3137174","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},{"id":"pmid:34965212","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34965212","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on visualization and computer graphics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2611657426","display_name":null,"funder_award_id":"IIS-1528203","funder_id":"https://openalex.org/F4320335353","funder_display_name":"National Science Foundation of Sri Lanka"},{"id":"https://openalex.org/G482769852","display_name":null,"funder_award_id":"IIS-1741536","funder_id":"https://openalex.org/F4320335353","funder_display_name":"National Science Foundation of Sri Lanka"}],"funders":[{"id":"https://openalex.org/F4320335353","display_name":"National Science Foundation of Sri Lanka","ror":"https://ror.org/010xaa060"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":97,"referenced_works":["https://openalex.org/W78661028","https://openalex.org/W1159969674","https://openalex.org/W1529527003","https://openalex.org/W1581627189","https://openalex.org/W1604647162","https://openalex.org/W1850550907","https://openalex.org/W1893631399","https://openalex.org/W1971318070","https://openalex.org/W1984453610","https://openalex.org/W1984939243","https://openalex.org/W1988494453","https://openalex.org/W1993889364","https://openalex.org/W1998837416","https://openalex.org/W2000618407","https://openalex.org/W2006096283","https://openalex.org/W2022893964","https://openalex.org/W2026812901","https://openalex.org/W2040184411","https://openalex.org/W2040682445","https://openalex.org/W2045407457","https://openalex.org/W2045619269","https://openalex.org/W2047167129","https://openalex.org/W2056132907","https://openalex.org/W2061821652","https://openalex.org/W2069392972","https://openalex.org/W2094435366","https://openalex.org/W2101135654","https://openalex.org/W2105897659","https://openalex.org/W2119026951","https://openalex.org/W2127309075","https://openalex.org/W2128179791","https://openalex.org/W2128261720","https://openalex.org/W2134611578","https://openalex.org/W2136487516","https://openalex.org/W2145378442","https://openalex.org/W2146427423","https://openalex.org/W2148479386","https://openalex.org/W2153554803","https://openalex.org/W2157931324","https://openalex.org/W2163925089","https://openalex.org/W2165250079","https://openalex.org/W2166669457","https://openalex.org/W2171208118","https://openalex.org/W2179422219","https://openalex.org/W2240390999","https://openalex.org/W2296227804","https://openalex.org/W2345733597","https://openalex.org/W2409767563","https://openalex.org/W2421101021","https://openalex.org/W2426912058","https://openalex.org/W2500960910","https://openalex.org/W2507619040","https://openalex.org/W2528553451","https://openalex.org/W2531872507","https://openalex.org/W2539068846","https://openalex.org/W2552765526","https://openalex.org/W2594593247","https://openalex.org/W2742434688","https://openalex.org/W2749215011","https://openalex.org/W2751731070","https://openalex.org/W2755129445","https://openalex.org/W2755790450","https://openalex.org/W2766098209","https://openalex.org/W2781096668","https://openalex.org/W2792404339","https://openalex.org/W2795875919","https://openalex.org/W2805191065","https://openalex.org/W2806322961","https://openalex.org/W2894440018","https://openalex.org/W2903517662","https://openalex.org/W2912949885","https://openalex.org/W2921301984","https://openalex.org/W2941265453","https://openalex.org/W2943864384","https://openalex.org/W2947115013","https://openalex.org/W2948356501","https://openalex.org/W2962502365","https://openalex.org/W2963214037","https://openalex.org/W2965010363","https://openalex.org/W2970898057","https://openalex.org/W2972845140","https://openalex.org/W2977883299","https://openalex.org/W2990368965","https://openalex.org/W3023141220","https://openalex.org/W3026072590","https://openalex.org/W3031494326","https://openalex.org/W3035192651","https://openalex.org/W3096100444","https://openalex.org/W3102822398","https://openalex.org/W3105164764","https://openalex.org/W3169843875","https://openalex.org/W3177269615","https://openalex.org/W4211044101","https://openalex.org/W4241074797","https://openalex.org/W4249491508","https://openalex.org/W6690448778","https://openalex.org/W6763266037"],"related_works":["https://openalex.org/W2362367986","https://openalex.org/W348707231","https://openalex.org/W4293108519","https://openalex.org/W3041760129","https://openalex.org/W2013728941","https://openalex.org/W4225274103","https://openalex.org/W2154046714","https://openalex.org/W2189613078","https://openalex.org/W2579659702","https://openalex.org/W2923661510"],"abstract_inverted_index":{"Diffusion":[0],"tensor":[1],"imaging":[2],"(DTI)":[3],"has":[4],"been":[5],"used":[6],"to":[7,20,100],"study":[8],"the":[9,39,68,78,82,86,130],"effects":[10],"of":[11,26,35,88,116,133],"neurodegenerative":[12],"diseases":[13,28],"on":[14,53],"neural":[15],"pathways,":[16],"which":[17],"may":[18],"lead":[19],"more":[21],"reliable":[22],"and":[23,60,73,85,108,126],"early":[24],"diagnosis":[25],"these":[27],"as":[29,31],"well":[30],"a":[32,43,95,114],"better":[33],"understanding":[34],"how":[36],"they":[37],"affect":[38],"brain.":[40],"We":[41,93,119],"introduce":[42],"predictive":[44],"visual":[45],"analytics":[46],"system":[47],"for":[48],"studying":[49],"patient":[50],"groups":[51],"based":[52],"their":[54],"labeled":[55],"DTI":[56,125],"fiber":[57],"tract":[58],"data":[59],"corresponding":[61],"statistics.":[62],"The":[63],"system's":[64],"machine-learning-augmented":[65],"interface":[66],"guides":[67],"user":[69],"through":[70,113],"an":[71],"organized":[72],"holistic":[74],"analysis":[75,106],"space,":[76,81,84],"including":[77],"statistical":[79],"feature":[80],"physical":[83],"space":[87,107],"patients":[89],"over":[90],"different":[91],"groups.":[92],"use":[94],"custom":[96],"machine":[97],"learning":[98],"pipeline":[99],"help":[101],"narrow":[102],"down":[103],"this":[104],"large":[105],"then":[109],"explore":[110],"it":[111],"pragmatically":[112],"range":[115],"linked":[117],"visualizations.":[118],"conduct":[120],"several":[121],"case":[122],"studies":[123],"using":[124],"T1-weighted":[127],"images":[128],"from":[129],"research":[131],"database":[132],"Parkinson's":[134],"Progression":[135],"Markers":[136],"Initiative.":[137]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}