{"id":"https://openalex.org/W1926682734","doi":"https://doi.org/10.1109/tvcg.2015.2467441","title":"NeuroBlocks \u2013 Visual Tracking of Segmentation and Proofreading for Large Connectomics Projects","display_name":"NeuroBlocks \u2013 Visual Tracking of Segmentation and Proofreading for Large Connectomics Projects","publication_year":2015,"publication_date":"2015-08-13","ids":{"openalex":"https://openalex.org/W1926682734","doi":"https://doi.org/10.1109/tvcg.2015.2467441","mag":"1926682734","pmid":"https://pubmed.ncbi.nlm.nih.gov/26529725"},"language":"en","primary_location":{"id":"doi:10.1109/tvcg.2015.2467441","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tvcg.2015.2467441","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049241635","display_name":"Ali K. Al-Awami","orcid":"https://orcid.org/0000-0002-8725-1958"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ali K. Ai-Awami","raw_affiliation_strings":["King Abdullah University of Science and Technology (KAUST)","King Abdullah University of Science & Technology (KAUST)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King Abdullah University of Science and Technology (KAUST)","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"King Abdullah University of Science & Technology (KAUST)","institution_ids":["https://openalex.org/I71920554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010238198","display_name":"Johanna Beyer","orcid":"https://orcid.org/0000-0002-3505-9171"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Johanna Beyer","raw_affiliation_strings":["School of Engineering and Applied Sciences, Harvard University",", School of Engineering and Applied Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering and Applied Sciences, Harvard University","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":", School of Engineering and Applied Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062859783","display_name":"Daniel Haehn","orcid":"https://orcid.org/0000-0001-9144-3461"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Haehn","raw_affiliation_strings":["School of Engineering and Applied Sciences, Harvard University",", School of Engineering and Applied Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering and Applied Sciences, Harvard University","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":", School of Engineering and Applied Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091300565","display_name":"Narayanan Kasthuri","orcid":"https://orcid.org/0000-0003-3825-931X"},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Narayanan Kasthuri","raw_affiliation_strings":["School of Medicine, Boston University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Boston University","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037495122","display_name":"Jeff W. Lichtman","orcid":"https://orcid.org/0000-0002-0208-3212"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210150141","display_name":"Center for Pain and the Brain","ror":"https://ror.org/04zxw0v05","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1288882113","https://openalex.org/I2801148111","https://openalex.org/I4210087915","https://openalex.org/I4210150141","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeff W. Lichtman","raw_affiliation_strings":["Center for Brain Science, Harvard University",", Center for Brain Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Science, Harvard University","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210150141"]},{"raw_affiliation_string":", Center for Brain Science","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043151044","display_name":"Hanspeter Pfister","orcid":"https://orcid.org/0000-0002-3620-2582"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanspeter Pfister","raw_affiliation_strings":["School of Engineering and Applied Sciences, Harvard University",", School of Engineering and Applied Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering and Applied Sciences, Harvard University","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":", School of Engineering and Applied Sciences","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008754293","display_name":"Markus Hadwiger","orcid":"https://orcid.org/0000-0003-1239-4871"},"institutions":[{"id":"https://openalex.org/I71920554","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38","country_code":"SA","type":"education","lineage":["https://openalex.org/I71920554"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Markus Hadwiger","raw_affiliation_strings":["King Abdullah University of Science and Technology (KAUST)","King Abdullah University of Science & Technology (KAUST)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King Abdullah University of Science and Technology (KAUST)","institution_ids":["https://openalex.org/I71920554"]},{"raw_affiliation_string":"King Abdullah University of Science & Technology (KAUST)","institution_ids":["https://openalex.org/I71920554"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.0245,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.9443609,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"22","issue":"1","first_page":"738","last_page":"746"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10799","display_name":"Data Visualization and Analytics","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/connectomics","display_name":"Connectomics","score":0.9443328976631165},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8577930927276611},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5803852677345276},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5394078493118286},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.40827077627182007},{"id":"https://openalex.org/keywords/connectome","display_name":"Connectome","score":0.19378846883773804}],"concepts":[{"id":"https://openalex.org/C2779097318","wikidata":"https://www.wikidata.org/wiki/Q2993446","display_name":"Connectomics","level":4,"score":0.9443328976631165},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8577930927276611},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5803852677345276},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5394078493118286},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.40827077627182007},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.19378846883773804},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003196","descriptor_name":"Computer Graphics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009488","descriptor_name":"Neurosciences","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009488","descriptor_name":"Neurosciences","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009488","descriptor_name":"Neurosciences","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/tvcg.2015.2467441","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tvcg.2015.2467441","pdf_url":null,"source":{"id":"https://openalex.org/S84775595","display_name":"IEEE Transactions on Visualization and Computer Graphics","issn_l":"1077-2626","issn":["1077-2626","1941-0506","2160-9306"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Visualization and Computer Graphics","raw_type":"journal-article"},{"id":"pmid:26529725","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26529725","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE transactions on visualization and computer graphics","raw_type":null},{"id":"pmh:oai:repository.kaust.edu.sa:10754/575258","is_oa":false,"landing_page_url":"http://hdl.handle.net/10754/575258","pdf_url":null,"source":{"id":"https://openalex.org/S4306401596","display_name":"King Abdullah University of Science and Technology Repository (King Abdullah University of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71920554","host_organization_name":"King Abdullah University of Science and Technology","host_organization_lineage":["https://openalex.org/I71920554"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1636961504","display_name":null,"funder_award_id":"OIA-1125087","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G1893723205","display_name":null,"funder_award_id":"OIA-1125087","funder_id":"https://openalex.org/F4320322320","funder_display_name":"King Abdullah University of Science and Technology"},{"id":"https://openalex.org/G6054415758","display_name":"CDI Type II: Bridging the Computational Semantic Gap: A Demand-Driven Framework for Portal-Based Chemistry, Astronomy and Neurobiology","funder_award_id":"1125087","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320322320","display_name":"King Abdullah University of Science and Technology","ror":"https://ror.org/01q3tbs38"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1533088900","https://openalex.org/W1588659438","https://openalex.org/W1971452799","https://openalex.org/W1973824709","https://openalex.org/W1981745715","https://openalex.org/W1983704199","https://openalex.org/W2001749563","https://openalex.org/W2012812717","https://openalex.org/W2019699016","https://openalex.org/W2021298267","https://openalex.org/W2021689070","https://openalex.org/W2022235653","https://openalex.org/W2030246490","https://openalex.org/W2034538997","https://openalex.org/W2037086593","https://openalex.org/W2040156859","https://openalex.org/W2051591260","https://openalex.org/W2058417985","https://openalex.org/W2058651674","https://openalex.org/W2075121582","https://openalex.org/W2097284091","https://openalex.org/W2106083403","https://openalex.org/W2106588364","https://openalex.org/W2107833399","https://openalex.org/W2109418048","https://openalex.org/W2110509604","https://openalex.org/W2116154101","https://openalex.org/W2125907229","https://openalex.org/W2126415191","https://openalex.org/W2138199375","https://openalex.org/W2147762902","https://openalex.org/W2158213074","https://openalex.org/W2160041854","https://openalex.org/W2163314583","https://openalex.org/W2166463343","https://openalex.org/W2171989756","https://openalex.org/W2320486025","https://openalex.org/W2952490026","https://openalex.org/W4292771360","https://openalex.org/W4297727673","https://openalex.org/W6635228124","https://openalex.org/W6674516820","https://openalex.org/W6684248457","https://openalex.org/W6811938030"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2807503652","https://openalex.org/W2212379672","https://openalex.org/W2424680827","https://openalex.org/W2079675757","https://openalex.org/W2912524409","https://openalex.org/W2532575085","https://openalex.org/W4251316676","https://openalex.org/W4323066529","https://openalex.org/W4242108457"],"abstract_inverted_index":{"In":[0],"the":[1,22,25,53,78,93,115,135,148,159,168,184,208],"field":[2],"of":[3,21,35,56,71,98,118,154,161,167,186,210],"connectomics,":[4],"neuroscientists":[5,121],"acquire":[6],"electron":[7],"microscopy":[8],"volumes":[9],"at":[10],"nanometer":[11],"resolution":[12],"in":[13,24,37,104,214],"order":[14],"to":[15,40,43],"reconstruct":[16],"a":[17,57,68,87,108,215],"detailed":[18],"wiring":[19],"diagram":[20],"neurons":[23],"brain.":[26],"The":[27],"resulting":[28],"image":[29],"volumes,":[30],"which":[31,85],"often":[32],"are":[33],"hundreds":[34],"terabytes":[36],"size,":[38],"need":[39],"be":[41],"segmented":[42],"identify":[44],"cell":[45,50],"boundaries,":[46],"synapses,":[47],"and":[48,64,73,96,126,131,152,174,179,200,206,212],"important":[49],"organelles.":[51],"However,":[52],"segmentation":[54,102,211],"process":[55],"single":[58],"volume":[59],"is":[60,86,107,134],"very":[61,99],"complex,":[62],"time-intensive,":[63],"usually":[65],"performed":[66],"using":[67],"diverse":[69,116],"set":[70,117],"tools":[72,119],"many":[74],"users.":[75],"To":[76],"tackle":[77],"associated":[79],"challenges,":[80,173],"this":[81,140],"paper":[82],"presents":[83],"NeuroBlocks,":[84,162],"novel":[88],"visualization":[89],"system":[90,137],"for":[91,124,147,204],"tracking":[92,207],"state,":[94],"progress,":[95],"evolution":[97],"large":[100,216],"volumetric":[101],"data":[103],"neuroscience.":[105],"NeuroBlocks":[106,133],"multi-user":[109],"web-based":[110],"application":[111],"that":[112,120,138,194],"seamlessly":[113],"integrates":[114,139],"currently":[122],"use":[123],"manual":[125],"semi-automatic":[127],"segmentation,":[128],"proofreading,":[129],"visualization,":[130],"analysis.":[132],"first":[136],"heterogeneous":[141],"tool":[142],"set,":[143],"providing":[144],"crucial":[145],"support":[146],"management,":[149],"provenance,":[150],"accountability,":[151],"auditing":[153],"large-scale":[155],"segmentations.":[156],"We":[157,182],"describe":[158],"design":[160,188],"starting":[163],"with":[164],"an":[165],"analysis":[166],"domain-specific":[169],"tasks,":[170],"their":[171,201],"inherent":[172],"our":[175,187],"subsequent":[176],"task":[177],"abstraction":[178],"visual":[180],"representation.":[181],"demonstrate":[183],"utility":[185],"based":[189],"on":[190,196],"two":[191],"case":[192],"studies":[193],"focus":[195],"different":[197],"user":[198],"roles":[199],"respective":[202],"requirements":[203],"performing":[205],"progress":[209],"proofreading":[213],"real-world":[217],"connectomics":[218],"project.":[219]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}